Caveolin 1 and lipid rafts in modulation of autophagy

... 20 1. 2 LIPID RAFTS AND CAV -1 27 1. 2 .1 Lipid rafts 27 1. 2.2 Caveolin- 1 33 1. 3 LIPID RAFTS AND CAV -1 IN AUTOPHAGY 35 1. 3 .1 Lipid rafts in autophagy 35 1. 3.2 ... 1. 1.3 Autophagy machinery 1. 1.4 Lysosome 10 1. 1.5 Regulatory pathways of autophagy 12 1. 1.6 Biological functions of autophagy 15 1. 1.7 Implication of autop...

Ngày tải lên: 09/09/2015, 08:13

... ,D( reyal mrofixelp retuo ni deniatsonummi ylesuffid saw 2-niloevaC )worra ,C( noitacol dna ygolohprom ni sllec relluM lacitnedi ,sllec lailg fo ssecorp eht ni dnuof saw gniniatsonummi-2-niloevaC ... dna ,02 -neewT %1.0 gniniatnoc SBT ni semit eerht dehsaw erew stolb ehT 2-niloevac ro ,1-niloevac rehtie tsniaga ydobitna esuom htiw h rof detabucni neht erew senarbmeM h rof )lCaN Mm 051 dna ,4....

Ngày tải lên: 07/08/2014, 18:21

... dnuof sa ,erac dna esu lamina yrotarobal rof selpicnirp detpecca yllanoitanretni eht htiw ecnadrocca ni detcudnoc saw hcraeser ehT Co32 ta elcyc krad h-21:thgil h-21 a no deniatniam dna ytilicaf ... sti ;IP dna syad ta noitaidarri retfa droc lanips eht ni ytivitcaeronummi PAFG ni esaercni tnacifingis a swohs hparg rab ehT :B )IP dna ,4 ,1 fo syad ta( sdroc lanips detaidarri dna lamron ni...

Ngày tải lên: 07/08/2014, 18:21

... determinant for Met and EGFR activation in A431 cells Adhesion-induced activation of Met and EGFR in A431 cells is independent of Src, ROS, or cytoskeleton Adhesion-induced activation of RTKs ... mM NaCl, 10% glycerol and mM Na3VO4) containing protease inhibitors (1 mM phenylmethylsulfonyl fluoride, 0.2 trypsin inhibitory units/ml aprotinin, and 20 µg/ml leupep...

Ngày tải lên: 10/08/2014, 10:20

... to bind lipid compounds within the different endolysosomal compartments [23] In this study, we examined whether iron loading of the liver epithelial cell line HepG2 in uenced the expression of ... stress, cell growth and lipid metabolism in the iron loaded HepG2 The results of the study revealed a new link between iron loading and lipid...

Ngày tải lên: 19/02/2014, 16:20

... regulate the function of ErbB2 (heterodimerization, signaling and metabolic fate) [10] We therefore analyzed the role of gangliosides in the association of ErbB2 with lipid rafts in mammary epithelial ... demonstrated a key role for gangliosides in the association of ErbB2 with lipid rafts in mammary epithelial HC11 cells This...

Ngày tải lên: 23/03/2014, 10:21

... in the MA of MoMLV and A-MLV Gag precursors (Table 1) [19] Strikingly, the motif is highly conserved within most γ-retroviruses (Table 1) and is absent in Gag of other retroviruses Caveolin-1 interacts ... interacts with Gag precursor of MLV Gag- Cav-1 co-localization, the presence of the putative CBD in MA of MLV and the high degree of conservatio...

Ngày tải lên: 20/06/2014, 01:20

... 258 Rajinder Raina et al Table Effects of chronic dermal application of cypermethrin on enzymes, blood glutathione and lipid peroxidation in Wistar rats Days after dermal application ... 181-193 Taplin D, Meinking TL Pyrethrins and pyrethroids in dermatology Arch Dermatol 1990, 126, 213-221 Trojanowski JQ Rotenone neurotoxicity: a new window on environmental causes of...

Ngày tải lên: 07/08/2014, 23:22

... 11, 13 and TIMP-1 and TIMP-2 and their distribution in tissue is shown in table The expression in all the cases of MMP-1 thus neoplastic, fibroblasts and endothelial cells, may indicate a link action ... action in the degradation of the stroma The expression of MMP-2 was present basically in the neoplastic cells In the case of MMP-9 most of the...

Ngày tải lên: 09/08/2014, 07:22

... Hanly JG, Isenberg DA, Kalunian K, Nived O, et al.: The reliability of the Systemic Lupus International Collaborating Clinics/American College of Rheumatology Damage Index in patients with systemic ... antibodies and nine (28%) had lupus anticoagulant TGF-β1 activation index: an in vitro measure of the in vivo efficiency of TGF-β1 activation To examine the ability of...

Ngày tải lên: 09/08/2014, 08:22

... at the mRNA level in mouse synovial fibroblasts IL-1β and TNF-α induce SYN expression through activation of Erk IL-1β induces the growth of synovial fibroblasts by activating the MAPK pathways ... Conclusion This study demonstrated that the proinflammatory cytokines IL-1β and TNF-α induce synovial fibroblast growth by upregulating the expre...

Ngày tải lên: 09/08/2014, 08:23

... processes Competing interests The authors declare that they have no competing interests Sulf-1 and Sulf-2 expression in murine temporomandibular joints joints Safranin O staining (a-c) and immunohistochemistry ... cartilage Sulf-1 and Sulf-2 are highly expressed in OA cartilage, especially in clusters and even in normal- appearing cartilage in OA joints The ability...

Ngày tải lên: 09/08/2014, 10:23

... Mayhew (19 95, table 1) gives the following estimates of the price level at selected dates based upon Phelps-Brown and Hopkins (19 56): 13 00 10 4.8; 14 70 10 4.6; 15 26 13 5 .1; 15 46 17 2.3; 15 61 289.3; 16 00ϭ478.3; ... present in the outburst of complaints about usury and excessive interest rates from the 15 60s onward A usury bill prohibiting interest in excess of...

Ngày tải lên: 09/08/2014, 19:22

... (19 98) ‘Central Bankers and Uncertainty’, Keynes Lecture in Economics, Oct 29 , reprinted in Proceedings of the British Academy, 10 1, 22 9– 71 (19 99) and in the Bank of England Quarterly Bulletin, ... Phillips (19 20 ), Keynes (19 30) or Meade (19 34), and Tobin’s (19 63) paper on ‘Commerical Banks as Creators of Money ’ 22 THE ENDOGENEITY OF MONEY See Sayer...

Ngày tải lên: 09/08/2014, 19:22

... straightforward: an increase in the stock of money in excess of the demand for money leads to the bidding up of prices as the ‘excess’ money is spent, continuing until the demand for money is again in balance ... Supply of Credit Money and the Demand for Deposits: A Reply’, Cambridge Journal of Economics, 23, 11 5 19 Bank of England (19 99) Economic Models at th...

Ngày tải lên: 09/08/2014, 19:22