Caveolin 1 and lipid rafts in modulation of autophagy

... 20 1. 2 LIPID RAFTS AND CAV -1 27 1. 2 .1 Lipid rafts 27 1. 2.2 Caveolin- 1 33 1. 3 LIPID RAFTS AND CAV -1 IN AUTOPHAGY 35 1. 3 .1 Lipid rafts in autophagy 35 1. 3.2 ... 1. 1.3 Autophagy machinery 1. 1.4 Lysosome 10 1. 1.5 Regulatory pathways of autophagy 12 1. 1.6 Biological functions of autophagy 15 1. 1.7 Implication of autophagy in ... CAV -1 AND LIPID RAFTS IN EARLY STAGE OF AUTOPHAGY 12 9 6.2 CAV -1 AND LIPID RAFTS IN LATE STAGE OF AUTOPHAGY 13 2 6.3 CAV -1 AND LIPID RAFTS IN BREAST CANCER REGULATION 13 4 6.4 CONCLUSIONS AND FUTURE...

Báo cáo khoa học: "Immunohistochemical study of caveolin-1 and -2 in the rat retina" pps

... ,D( reyal mrofixelp retuo ni deniatsonummi ylesuffid saw 2-niloevaC )worra ,C( noitacol dna ygolohprom ni sllec relluM lacitnedi ,sllec lailg fo ssecorp eht ni dnuof saw gniniatsonummi-2-niloevaC ... dna ,02 -neewT %1.0 gniniatnoc SBT ni semit eerht dehsaw erew stolb ehT 2-niloevac ro ,1-niloevac rehtie tsniaga ydobitna esuom htiw h rof detabucni neht erew senarbmeM h rof )lCaN Mm 051 dna ,4.7 ... ot degufirtnec neht dna )nitpepuel lm/gµ 01 ,ninitorpa lm/gµ 01 ,FSMP Mm ,4OV3aN Mm ,04 tedinoN %1.0 ,lCaN Mm 021 ,sirT Mm 04( reffub sisyl ni dezinegomoh yletarapes erew star morf straeh dna...

Báo cáo khoa học: "Gamma-ray irradiation stimulates the expression of caveolin-1 and GFAP in rat spinal cord: a study of immunoblot and immunohistochemistry" pot

... dnuof sa ,erac dna esu lamina yrotarobal rof selpicnirp detpecca yllanoitanretni eht htiw ecnadrocca ni detcudnoc saw hcraeser ehT Co32 ta elcyc krad h-21:thgil h-21 a no deniatniam dna ytilicaf ... sti ;IP dna syad ta noitaidarri retfa droc lanips eht ni ytivitcaeronummi PAFG ni esaercni tnacifingis a swohs hparg rab ehT :B )IP dna ,4 ,1 fo syad ta( sdroc lanips detaidarri dna lamron ni ... morf sniloevac fo noitaziretcarahc dna noitacifirup-ytiniffA T otomakO ,PM itnasiL ,SW enaL ,H awazireS ,G llessaB ,LA dryB ,F itaiblaG ,D etnoloV ,FJ ahS ,K amayihsiN ,DB pparT ,H adeU ,T uzekI...

Báo cáo y học: "Involvement of lipid rafts in adhesion-induced activation of Met and EGF" pdf

... determinant for Met and EGFR activation in A431 cells Adhesion-induced activation of Met and EGFR in A431 cells is independent of Src, ROS, or cytoskeleton Adhesion-induced activation of RTKs ... mM NaCl, 10% glycerol and mM Na3VO4) containing protease inhibitors (1 mM phenylmethylsulfonyl fluoride, 0.2 trypsin inhibitory units/ml aprotinin, and 20 µg/ml leupeptin) The lysates were centrifuged ... Involvement of lipid rafts in adhesion-induced activation of Met and EGFR Ying-Che Lu1 and Hong-Chen Chen1,2,3,4* Graduate Institute of Biomedical Sciences, National Chung Hsing University,...

Tài liệu Báo cáo khoa học: Altered expression of CD1d molecules and lipid accumulation in the human hepatoma cell line HepG2 after iron loading pptx

... to bind lipid compounds within the different endolysosomal compartments [23] In this study, we examined whether iron loading of the liver epithelial cell line HepG2 in uenced the expression of ... stress, cell growth and lipid metabolism in the iron loaded HepG2 The results of the study revealed a new link between iron loading and lipid accumulation, leading to upregulation of CD1d molecules ... background staining (thin lines) Cells were then acquired in a FACScalibur and analyzed using CELLQUEST (A) Histograms show the expression of the molecules studied in HepG2 cells cultured in the absence...

Báo cáo khoa học: Role of gangliosides in the association of ErbB2 with lipid rafts in mammary epithelial HC11 cells docx

... regulate the function of ErbB2 (heterodimerization, signaling and metabolic fate) [10] We therefore analyzed the role of gangliosides in the association of ErbB2 with lipid rafts in mammary epithelial ... demonstrated a key role for gangliosides in the association of ErbB2 with lipid rafts in mammary epithelial HC11 cells This ﬁnding was strongly supported by the observation that addition of GM3 after ... role in retaining ErbB2 and proteins correlated with its signaltransduction pathway in lipid rafts A B C D Results ErbB2 GM3 colocalization in mammary epithelial HC11 cells In order to evaluate ErbB2...

Báo cáo hóa học: " Caveolin-1 interacts with the Gag precursor of murine leukaemia virus and modulates virus production" docx

... in the MA of MoMLV and A-MLV Gag precursors (Table 1) [19] Strikingly, the motif is highly conserved within most γ-retroviruses (Table 1) and is absent in Gag of other retroviruses Caveolin-1 interacts ... interacts with Gag precursor of MLV Gag- Cav-1 co-localization, the presence of the putative CBD in MA of MLV and the high degree of conservation among γ-retroviruses motivated us to investigate whether ... Profile analysis of Cav-1 and Gag RFP fluorescence in NIH3T3 cells Profile was drawn by Zeiss software and depicts the intensity distribution (B) in the channels detecting GagRFP (red) and caveolin-1...

Báo cáo khoa học: " Induction of oxidative stress and lipid peroxidation in rats chronically exposed to cypermethrin through dermal application" pps

... 258 Rajinder Raina et al Table Effects of chronic dermal application of cypermethrin on enzymes, blood glutathione and lipid peroxidation in Wistar rats Days after dermal application ... 181-193 Taplin D, Meinking TL Pyrethrins and pyrethroids in dermatology Arch Dermatol 1990, 126, 213-221 Trojanowski JQ Rotenone neurotoxicity: a new window on environmental causes of Parkinson’s ... be attacking the thiol group of cysteine residuse and polyunsaturated fatty acids of biological membranes [6] Free radical-induced lipid peroxidation resulting in the deterioration of biological...

Báo cáo khoa học: "Expression of the metalloproteases MMP-1, MMP-2, MMP-3, MMP-9, MMP-11, TIMP-1 and TIMP-2 in angiocentric midfacial lymphomas" potx

... 11, 13 and TIMP-1 and TIMP-2 and their distribution in tissue is shown in table The expression in all the cases of MMP-1 thus neoplastic, fibroblasts and endothelial cells, may indicate a link action ... action in the degradation of the stroma The expression of MMP-2 was present basically in the neoplastic cells In the case of MMP-9 most of the cases were negative both tumoral and reactive cells The ... cellular components of the vascular wall On the other hand, 12 cases of the present series showed a more intense expression of TIMP-1 in epithelial cells, mainly the mucosal gland, whose structures...

Báo cáo y học: "Activation of transforming growth factor-β1 and early atherosclerosis in systemic lupus erythematosus" pptx

... Hanly JG, Isenberg DA, Kalunian K, Nived O, et al.: The reliability of the Systemic Lupus International Collaborating Clinics/American College of Rheumatology Damage Index in patients with systemic ... antibodies and nine (28%) had lupus anticoagulant TGF-β1 activation index: an in vitro measure of the in vivo efficiency of TGF-β1 activation To examine the ability of SLE patients and control individuals ... TGF-β1, a ratio of levels of TGF-β1 in freshly collected blood and after 90 minutes of clotting at 37°C was determined The degranulation of platelets during clotting results in release of excess latent...

Báo cáo y học: "The proinflammatory cytokines IL-1β and TNF-α induce the expression of Synoviolin, an E3 ubiquitin ligase, in mouse synovial fibroblasts via the Erk1/2-ETS1 pathway" ppt

... at the mRNA level in mouse synovial fibroblasts IL-1β and TNF-α induce SYN expression through activation of Erk IL-1β induces the growth of synovial fibroblasts by activating the MAPK pathways ... Conclusion This study demonstrated that the proinflammatory cytokines IL-1β and TNF-α induce synovial fibroblast growth by upregulating the expression of an E3 ubiquitin ligase, SYN At the molecular ... production of proinflammatory cytokines by synovial macrophages and fibroblasts is one reason for synovial cell hyperproliferation We therefore hypothesized that some of these cytokines may also...

Báo cáo y học: "Expression of novel extracellular sulfatases Sulf-1 and Sulf-2 in normal and osteoarthritic articular cartilage" pdf

... processes Competing interests The authors declare that they have no competing interests Sulf-1 and Sulf-2 expression in murine temporomandibular joints joints Safranin O staining (a-c) and immunohistochemistry ... cartilage Sulf-1 and Sulf-2 are highly expressed in OA cartilage, especially in clusters and even in normal- appearing cartilage in OA joints The ability of Sulfs to regulate growth factor pathways (such ... Mankin score: to points) as determined by real-time PCR (Figure 1) Localization of Sulf-1 and Sulf-2 proteins in human articular cartilage Young and old normal samples as seen on safranin O staining...

money macroeconomics and keynes essays in honour of victoria chick volume 1 phần 1 docx

... Mayhew (19 95, table 1) gives the following estimates of the price level at selected dates based upon Phelps-Brown and Hopkins (19 56): 13 00 10 4.8; 14 70 10 4.6; 15 26 13 5 .1; 15 46 17 2.3; 15 61 289.3; 16 00ϭ478.3; ... present in the outburst of complaints about usury and excessive interest rates from the 15 60s onward A usury bill prohibiting interest in excess of 10 per cent was introduced in 15 71 and cases of ... output and employment 15 .5 Impact of cheap money on the individual member-state ix 63 15 2 15 3 15 7 15 7 15 8 TABLES 6 .1 Cases I, II and III 8 .1 Patterns of development finance in different financial...

money macroeconomics and keynes essays in honour of victoria chick volume 1 phần 2 pot

... (19 98) ‘Central Bankers and Uncertainty’, Keynes Lecture in Economics, Oct 29 , reprinted in Proceedings of the British Academy, 10 1, 22 9– 71 (19 99) and in the Bank of England Quarterly Bulletin, ... Phillips (19 20 ), Keynes (19 30) or Meade (19 34), and Tobin’s (19 63) paper on ‘Commerical Banks as Creators of Money ’ 22 THE ENDOGENEITY OF MONEY See Sayers (19 76, chapter 3, especially p 28 ) Also ... Chick, V (19 73) The Theory of Monetary Policy, revised edn Oxford: Basil Blackwell Chick, V (19 92) ‘The Evolution of the Banking System and the Theory of Saving, Investment and Interest’, in...

money macroeconomics and keynes essays in honour of victoria chick volume 1 phần 3 doc

... straightforward: an increase in the stock of money in excess of the demand for money leads to the bidding up of prices as the ‘excess’ money is spent, continuing until the demand for money is again in balance ... Supply of Credit Money and the Demand for Deposits: A Reply’, Cambridge Journal of Economics, 23, 11 5 19 Bank of England (19 99) Economic Models at the Bank of England London: Bank of England Chick, ... stimulating effect from the expectation of rising prices (Keynes 19 36 : 14 3) To see this more formally, consider Chick s (19 83: 12 0) definition of the marginal efficiency of capital The marginal...

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