Epigenetic regulation of normal and malignant hematopoiesis

Epigenetic regulation of normal and malignant hematopoiesis

... in normal hematopoiesis and leukemia The methylation of histones on lysine and arginine residues by HMTs represents another level of gene regulation, and is probably the most complex of the epigenetic ... silencing (Cao et al., 2005) Oncogene Epigenetic regulation of hematopoiesis KL Rice et al 6704 Table Substrate speciﬁcity of HKMTs and involvement of norma...

Ngày tải lên : 05/09/2015, 11:25

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Báo cáo khoa học: Enzymes of creatine biosynthesis, arginine and methionine metabolism in normal and malignant cells Soumen Bera1, Theo Wallimann2, Subhankar Ray1 and Manju Ray1 potx

... homocysteine to methionine Tissue metabolism of arginine and methionine is of high importance for the effective regulation of cell death and survival in normal as well as in tumor cells Polyamines ... expression of different enzymes involved in arginine and methionine metabolism because these enzymes are intimately related to creatine biosynthesis (...

Ngày tải lên : 07/03/2014, 04:20

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Regulation of navigation and vessel-source pollution in the Northern Sea Route - Article 234 and state practice

... (NSRA), including the Guide to Navigating through the Northern Sea Route (NSR Navigation Guide) and the Requirements for the Design, Equipment and Supplies of Vessels Navigating the Northern Sea Route ... adjoining the USSR northern coast and that it includes seaways suitable for guiding vessels in ice Due to the vagueness concerning leading in Artic...

Ngày tải lên : 01/11/2013, 09:20

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Tài liệu Báo cáo khoa học: Roles of AP-2 transcription factors in the regulation of cartilage and skeletal development doc

... role of AP-2a and AP-2e in chondrogenesis Overview of the differentiation stages during chondrogenesis and the involvement of transcription factors (henatoxylin and eosin-stained section of an ... analyses of the regulation of AP-2 and the interactions of the transcription factor with binding partners, as well as of the regulation of target...

Ngày tải lên : 16/02/2014, 09:20

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$Tài liệu Báo cáo khoa học: Comparison of membrane fraction proteomic proﬁles of normal and cancerous human colorectal tissues with gel-assisted digestion and iTRAQ labeling mass spectrometry pptx$

Tài liệu Báo cáo khoa học: Comparison of membrane fraction proteomic proﬁles of normal and cancerous human colorectal tissues with gel-assisted digestion and iTRAQ labeling mass spectrometry pptx

... We used iTRAQ labeling together with gel-assisted digestion and mass spectrometry to detect differences in the protein expression proﬁles of membrane fractions from tumoral and adjacent normal ... tags with related and absolute quantitation (iTRAQ) labeling and LC-MS ⁄ MS for quantitative analysis of the membrane proteome of colorectal tissue In brief...

Ngày tải lên : 16/02/2014, 15:20

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Báo cáo khoa học: Nuclear actin and actin-binding proteins in the regulation of transcription and gene expression docx

... 2675 Actin and ABPs in transcription regulation B Zheng et al Table Role of nuclear actin- binding proteins interacting with the androgen receptor AR, androgen receptor; LBD, ligand-binding domain ... STARS-interacting proteins These novel proteins contain four LIM domains and a C-terminal villin headpiece domain, which mediates actin- binding in several proteins,...

Ngày tải lên : 07/03/2014, 01:20

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Báo cáo khoa học: Huntington’s disease: roles of huntingtin-interacting protein 1 (HIP-1) and its molecular partner HIPPI in the regulation of apoptosis and transcription pptx

... Htt-interacting protein HIP -1 and its molecular partner HIPPI in the regulation of apoptosis and transcription, the two processes that are altered in HD [7,8] HIP -1 – its interacting partners and ... Conclusions HIP -1 and its interacting partner HIPPI together induce apoptosis by the intrinsic and extrinsic pathways Homer 1c, an interactor...

Ngày tải lên : 23/03/2014, 07:20

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Báo cáo Y học: Molecular characterization of MRG19 of Saccharomyces cerevisiae Implication in the regulation of galactose and nonfermentable carbon source utilization pdf

... containing galactose as a carbon source Wild-type and mrg19 strains grew on galactose plates within 12 h while gal3 strain showed the characteristic delay in growth on galactose Interestingly, the ... disruption of MRG19 might effect GAL induction only at low galactose concentrations This hypothesis was tested by monitoring galactokinase induction as a function of...

Ngày tải lên : 31/03/2014, 08:20

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báo cáo hóa học: " Muscle-driven forward dynamic simulations for the study of normal and pathological gait" potx

... support of the trunk, in mid-stance gastrocnemius increases the stance leg energy and restrains the forward motion of the trunk; soleus has the opposite effects In late stance, the initiation of swing ... regarding the role of the plantarflexors in propulsion, but their study examined the accelerations of the hip rather than the trunk COM [40] Dynamic s...

Ngày tải lên : 19/06/2014, 10:20

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Báo cáo khoa học: "Infrared spectroscopy characterization of normal and lung cancer cells originated from epithelium" pdf

... band at ∼1,650 cm 󰠏1 Table Spectral data and vibrational assignments of normal and lung cancer cells* Normal cells † (NHBE ) Cancer cells (NCI-H358) Cancer cells (NCI-H460) 1,649 1,548 1,456 1,400 ... lung cancer cells The NCI-H460 lung cancer cells originated from a patient with large cell cancer of the lung (ATCC catalog number: HTB-177), which...

Ngày tải lên : 07/08/2014, 23:22

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Báo cáo y học: "α Impact of VIP and cAMP on the regulation of TNF-α and IL-10 production: implications for rheumatoid arthritis" pps

... compared the effects of VIP, rolipram, and dibutyryl cAMP on the production of TNF-α and IL-10 by monocytes Spontaneous production of IL-10 and TNF-α by monocytes could not be detected; cytokine ... macrophage IL-10 production We wished to investigate VIP regulation of cAMP levels in monocytes and macrophages upon stimulation by LPS and PMA/ionomycin...

Ngày tải lên : 09/08/2014, 01:23

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Báo cáo y học: "Analysis of normal and osteoarthritic canine cartilage mRNA expression by quantitative polymerase chain reacti" potx

... review of naturally occurring human OA and experimental canine OA and from the results of a preliminary caninespecific whole genome microarray study, using a small number of samples Assays were ... quantification of expression of five collagen genes (type I collagen, alpha chain [COL1A2], type II collagen alpha chain [COL2A1], type III collagen alpha chain [COL3A1], ty...

Ngày tải lên : 09/08/2014, 08:22

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Báo cáo y học: "T-cell contact-dependent regulation of CC and CXC chemokine production in monocytes through differential involvement of NFκB: implications for rheumatoid arthritis" docx

... inverted pattern of utilization of NFκB for the T-cell contact-dependent induction of CC and CXC chemokines in monocytes is surprising and indicates that chemokine gene expression may be more complex ... same system of adenovirally mediated IκBα overexpression in M-CSF-differentiated monocytes to investigate the potential involvement of NFκB in the expressi...

Ngày tải lên : 09/08/2014, 08:23

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Báo cáo y học: "Effect of interleukin-1β on spinal cord nociceptive transmission of normal and monoarthritic rats after disruption of glial function" pot

... dorsal horn neurons [14,15] In order to study the contribution of glial activation and the associated upregulated expression of IL-1β on spinal cord nociceptive transmission in arthritic rats, we used ... inflammation and damage of peripheral tissues, the spinal cord responds with a robust glial reaction characterized by proliferation, hypertrophy, decreased ramif...

Ngày tải lên : 09/08/2014, 14:22

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Báo cáo y học: "Composition and regulation of maternal and zygotic transcriptomes reflects species-specific reproductive mode" doc

... strict -maternal, mostly -maternal, maternal- zygotic and mostly -zygotic, respectively) Strikingly, the 5' IGR lengths of the small set of 282 genes belonging to the strict -zygotic class are extremely ... regulatory architecture of maternal and zygotic genes across the animal kingdom highlights the complexity of regulation of mammalian maternal genes To analyze the...

Ngày tải lên : 09/08/2014, 20:22

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