Genetic modifier of beta thalassemia

... the specific effects of genetic modifiers of the clinical severity of β -thalassemia While it is likely that future whole genome sequencing studies will better define the genetic polymorphisms ... genotypes including mild/silent β -thalassemia alleles, coinheritance of α -thalassemia or the presence of genetic determinants associated with increased production of γ-globin...

Ngày tải lên: 27/08/2015, 09:28

... article as: Ishaq and Shabbir: Takayasu’s arteritis presenting with temporary loss of vision in a 23-year-old woman with beta thalassemia trait: a case report Journal of Medical Case Reports 2011 5:466 ... is an essential part of managing such patients in our setting, where beta thalassemia trait testing is not done routinely Conclusion The simult...

Ngày tải lên: 10/08/2014, 23:20

... polymorphisms and risk of esophageal cancer, we found that variant 72Pro of alleles p53 Arg72Pro could significantly increase the risk of esophageal cancer, although the association were not significantly ... 2000 China Asian Lee JM[22] 2000 China(Taiwan) Asian Casson AG[21] 2003 Canada Caucasian Roth MJ[32] 2004 China Asian Casson AG[20] 2006 Canada Caucasian Cai L[25] 20...

Ngày tải lên: 25/10/2012, 11:40

... on Murrah buffaloes maintained at Central cattle breeding farm, Alamadi, Tamilnadu Individual blood samples of ml each were collected from 110 Murrah buffaloes using ml vacuitainer tubes containing ... IV to intron IV (enclosing 94 base pairs of exon IV and 168 base pair of intron IV ) and resulted in 262 bp fragment in cattle The same primers were used for amplifying b-lg...

Ngày tải lên: 18/02/2014, 02:20

... examine the effect of the APOH promoter SNPs on plasma b2GPI levels; and (d) to determine the cross-species conservation of the APOH promoter sequence To identify regions of the APOH promoter that ... quantitative change at the protein level Whether the APOH promoter SNPs ()643T>C and )1219G>A) could influence the promoter activity by either the former or...

Ngày tải lên: 15/03/2014, 10:20

... this minireview is to summarize what is currently known about the molecular mechanisms of osmotic stress resistance, osmosensing and signal transduction in C elegans Osmosensing and signaling in ... process of interest, allows genes to be ordered into pathways, and can provide important and novel mechanistic insights into the molecular structure and functio...

Ngày tải lên: 30/03/2014, 03:20

... cytoplasm So all the mitochondria and other plastids in the cytoplasm of the first cell of the new embryo are derived from the maternal parent There are some exceptions to this general mode of fertilization, ... the amount of DNA belonging to a haploid nucleus, expressed in picograms (10–12 g) This is an indicator of the size of the nuclear genome It has become cle...

Ngày tải lên: 20/04/2014, 14:26

... expressed in the tapetum, the tissue in the anther from which pollen-mother cells develop As a precaution 36 • SEEDS OF CONCERN against barnase being accidentally expressed in any other part of ... the amount of DNA belonging to a haploid nucleus, expressed in picograms (10–12 g) This is an indicator of the size of the nuclear genome It has become clear that the si...

Ngày tải lên: 24/04/2014, 14:00

Ngày tải lên: 02/05/2014, 06:20

... (hPBMC) hPBMC (human peripheral mononuclear cell) beta-glucan (60µg/ml ) beta-glucan (30µg/ml)  PHA (Phytohemagglutinin) - a kind of mitogen beta-glucan (60µg/ml) µg/ml ) PHA(1 control 3000 6000 ... lượng, không gây béo phì Beta-glucan làm viêôc nào? Giảm thấp cholesterol, từ làm giảm tai biến mạch máu não Beta-glucan yếu tố chìa khóa kích thích tế bào kháng thê Beta-glucan...

Ngày tải lên: 18/06/2014, 12:20

... activity of Ad5. PTDtat Unmodified Ad5 viruses interact with their native receptor CAR via the fiber knob domain We thus examined whether incorporation of PTDtat into the knob domain interfered with the ... efficacy of Ad5. PTDtat We further investigated the gene transfer efficacy of Ad5. PTDtat in a variety of cultured cells using the reporter GFP prot...

Ngày tải lên: 18/06/2014, 18:20

... propagation of the virus Amino acid comparison of the Leader protease Figure displays the alignment of the deduced amino acid sequence of the first 96 residues of the FMDV Leader protease from the A/IRN/05 ... on the epidemiology of FMDV in Pakistan Open Session of the Research Group of the European Commission for the Control of Foot-and-Mouth Dise...

Ngày tải lên: 18/06/2014, 18:20

... Detailed genetic analysis of hemagglutininneuraminidase glycoprotein gene in human parainfluenza virus type isolates from patients with acute respiratory infection between 2002 and 2009 in Yamagata prefecture, ... HPIVi /Yamagata /2009/ 25 81 HPIVi /Yamagata /2009/ 2009 HPIVi /Yamagata /2009/ 2075 HPIVi /Yamagata /2009/ 2055 HPIVi /Yamagat...

Ngày tải lên: 18/06/2014, 18:20