Case study cancer risk assessment dec 12 compatibility mode

... determined from the study 12/ 8/2010 Reference Dose for Alachlor The NOEL in the chronic rat study of 0.5 mg/kg/day was considered to be the appropriate endpoint for establishing the non -cancer RfD for ... (MOE) approach for the purpose of risk assessment of alachlor Since there were rare tumors seen with alachlor exposure in animal studies, for the purposes of risk assessment,...

Ngày tải lên: 15/04/2015, 08:43

... applied in calculating the chronic Population Adjusted Dose (cPAD) Acute Dietary Risk Assessment A revised acute dietary risk analysis was conducted with the DEEM The exposure at a maximum was ... mg/kg/day cPAD = aRfD 10 = 0.0003 mg/kg/day = 0.00003 mg/kg/day 10 Chronic Dietary Risk Assessment A chronic dietary risk analysis was conducted using the DRES analysis Using DRE...

Ngày tải lên: 15/04/2015, 08:43

... for some endpoints (carcinogens, allergens?) Risk Characterization of Carcinogens Class of carcinogen Potency consideration (possibly risk figure) Mode/ mechanism of action Descriptive statement ... concerning safety and potential risks Definition of risk management /risk reduction needs Exposure Considerations Exposures from all sources and through various media Risk comparison o...

Ngày tải lên: 17/04/2015, 08:38

... affected? Individual risk Voluntary or accepted risk? Benefits from accepting risk FACTORS CAUSING OUTRAGE FACTORS AFFECTING RISK PERCEPTION FACTOR Potentially uncontrollable risks Ability to cause ... IMPLICATIONS FOR RISK ASSESSMENT AND MANAGEMENT Stakeholder involvement in all stages of risk assessment Addressing public concerns adequately Consider risk perception issues i...

Ngày tải lên: 16/04/2015, 08:49

... this article as: Tanaka et al., A case study of new assessment and training of unilateral spatial neglect in stroke patients: effect of visual image transformation and visual stimulation by using ... images In Master's the-sis Industrial Engineering, University of Washington; 1993 Tanaka T, Nara H, Ino S, Ifukube T: Clinical Application o...

Ngày tải lên: 19/06/2014, 08:20

... Breast cancer risk assessment with five independent genetic variants and two risk factors in Chinese women Juncheng Dai1,2,3, Zhibin Hu1,2,3, Yue Jiang1, Hao Shen1, Jing Dong1, Hongxia Ma1, Hongbing ... breast cancer marker SNPs in this Chinese population Then, we grouped the marker SNPs, and modeled them with clinical risk factors, to see the usage of...

Ngày tải lên: 21/06/2014, 19:20

... on Risk Assessment and Risk Management1 states: [I]t is time to modify the traditional approaches to assessing and reducing risks that have relied on a chemical-by-chemical, medium-by-medium, risk- by -risk ... REFERENCES Presidential/Congressional Commission on Risk Assessment and Risk Management, Risk Assessment and Risk Management in Regulatory Decision-Making F...

Ngày tải lên: 08/08/2014, 10:22

... Petron, S., Potocki, B., Svirsky, S., and Tyler, P 1996 A weight-of-evidence approach for evaluating ecological risks: report of the Massachusetts Weight-of-Evidence Work Group, Hum Ecol Risk Assess., ... for regional and comparative ecological risk assessment, Hum Ecol Risk Assess, 3, 287–297 © 2005 by CRC Press LLC L1655_book.fm Page 256 Wednesday, September 22, 2004 10:18 AM 2...

Ngày tải lên: 11/08/2014, 20:21

... issues of concern in this case study Formulate the health problem you would like to address with your human health risk assessment - Follow the roadmaps in the Toolkit for (a) hazard identification; ... Follow the roadmap in the Toolkit for exposure assessment and address the questions mentioned there - Discuss from where you can get exposure information that is needed for your risk...

Ngày tải lên: 15/04/2015, 08:43

... contains rice Is this use safe for acute exposures ? Chronic exposures ? LongLong-Term versus Short-Term ShortExposure Estimates LongLong-Term versus Short-Term ShortExposure Estimates For this example ... in a chronic exposure assessment, the use of median residue levels is not appropriate and results at the high end of the residue distribution should be used in an acute exposure asses...

Ngày tải lên: 15/04/2015, 09:20

... overall the model focuses researchers and managers on the WHY of strategic change with relevance to context; the WHAT of strategic change in terms of its content; and the HOW of strategic change ... How and which implementation and other change strategies are used to achieve change at both the individual team and organizational levels relative to suc...

Ngày tải lên: 11/08/2014, 05:22

... by-products WHO Guidelines for Drinking-Water Quality: Drinkingderivation of GVs: non-threshold substances non- WHO Guidelines for Drinking-Water Quality: Drinkingprovisional guideline values ... • a guideline is not necessarily a standard • international guidelines are available for various media, chemicals, and commodities to assist countries in the process of standard setting setting...

Ngày tải lên: 15/04/2015, 09:19

... deaths TABLE Characteristics of cases and two control groups: Population- based case -control study of smoking on risk of cancer deaths among Chinese men 1989–1991 Characteristic Cases No of subjects ... sex-matched living spouse control design as an alternative control selection for a nationwide population- based case -control study is valid and feasib...

Ngày tải lên: 26/10/2012, 09:48