... rationale for safety Further, it is clear that safety with an antibody is not the same as safety with a T cell; antibody studies therefore cannot substitute for directed designer T cell trials via ... against the most intensive Strategies for untested antigen targets If by an early Strategy, the patient can safely be treated, then one may reasonably advance to more potent Strategies with a rationale ... inadequate (and safe) under Strategy infusions, then engraftment via Strategy with its higher cost and hazard is a justifiable next step in the Strategy Escalation Hence, for untested targets, it is...