arsenic binding to hemoglobin and its role in arsenic distribution, metabolism, and toxicity

... [8] and Ras guanine exchange factor (RasGEF) very- KIND (v-KIND, or kinase noncatalytic C-lobe domain containing 1) [9]. The KIND domain in these proteins is localized to the N-terminal region, and ... 2011 The Authors Journal compilation ê 2011 FEBS Interaction between very-KIND Ras guanine exchange factor and microtubule-associated protein...

Ngày tải lên: 14/02/2014, 19:20

... of wild-type occludin (Occ WT ) and variant occludin in apoptosis and invasion, as determined by assay, we revealed that exon 9 played a major role in the induc- tion of mitochondria-mediated apoptosis and ... (sense) and 5Â-GAAAAAACGCGATCCTACTT-3Â (antisense). Primers for unmethylated DNA were: 5Â-GAAGTAGGTGGAGT ATTGAAT-3Â (sense) and 5Â-CAAAAAAACACAATCCT...

Ngày tải lên: 18/02/2014, 18:20

... 2006 The Authors Journal compilation ª 2006 FEBS 4263 High < /b> affinity < /b> copper < /b> binding < /b> by < /b> stefin < /b> B (cystatin B) and its role in the inhibition of amyloid fibrillation Eva Z ˇ erovnik 1 , Katja S ˇ kerget 1 , ... number of histidines in the C-terminus (box in Fig. 1) at sites: 92, 75, 66 and 58. As histidine residues a...

Ngày tải lên: 19/02/2014, 06:20

... 2021 Biochemical characterization of human 3-methylglutaconyl-CoA hydratase and its role in leucine metabolism Matthias Mack 1 , Ute Schniegler-Mattox 2 , Verena Peters 3 , Georg F. Hoffmann 3 , ... another function in cellular metabolism. Indeed, AUH had enoyl-CoA hydratase activity, which was described as an additional intrinsic function of the protein. Its...

Ngày tải lên: 19/02/2014, 07:20

... FEBS 2003 Roundworm pyrophosphatase (Eur. J. Biochem. 270) 2821 Inorganic pyrophosphatase in the roundworm Ascaris and its role in the development and molting process of the larval stage parasites M. ... concerning the kinetics and properties of the enzyme. More strikingly, we show a novel role of the PPase enzyme in the developm...

Ngày tải lên: 20/02/2014, 11:20

... regulation of caspases. Taken together, these results indicate that VBARP is a novel splice variant of ANKHD1 and may play a role in cellular apoptosis (antiapoptotic) and cell survival pathway(s). Abbreviations ANK, ... characterization of a novel splice variant of ANKHD1 that lacks the KH domain and its role in cell surviv...

Ngày tải lên: 07/03/2014, 21:20

... Lockheed Martin Corporation (retired) JOSEPH K. ALEXANDER, Director Appendixes 8 SOLAR AND SPACE PHYSICS AND ITS ROLE IN SPACE EXPLORATION variations in solar output so as to understand their ... Lennard A. Fisk, Chair Space Studies Board 6 SOLAR AND SPACE PHYSICS AND ITS ROLE IN SPACE EXPLORATION FIGURE 1.1 The heliospheric systemthe Sun...

Ngày tải lên: 14/03/2014, 10:20

... T. brucei because the level of PEX14 mRNA in these cells was significantly lower (not shown). In order to determine the in uence of the reduction of the expression of TbPEX14 on the import of glycosomal ... identified in yeast) PEX17. Several other peroxins are involved in the subsequent steps of the import. The import of matrix proteins see...

Ngày tải lên: 23/03/2014, 17:21

... tolerance in the thymus. Competing interests None declared. References 1. Delon J, Stoll S, Germain RN: Imaging of T-cell interactions with antigen presenting cells in culture and in intact lymphoid tissue. ... B7/CD28- dependent and -independent induction of CD40 ligand expression. J Immunol 1995, 155:5124-5 132 . 9. Curtsinger JM, Schmidt CS, Mondino A, Lins DC, Kedl RM, Jenkins M...

Ngày tải lên: 09/08/2014, 01:23

... b-catenin, increasing intest inal b-cat enin signal- ing and cell proliferation. Also, increase in small-intestinal mucosa b-catenin in Per2 m/m mice is associated wi th an increase in MYC protein, ... temporally coordinated physiology [23-25]. Indirect synchronization is achieved by controlling d aily activity-rest cycles and, as a conse- quence, feeding time. Feeding (or starving)...

Ngày tải lên: 10/08/2014, 09:20

... Access Commentary Beyond the first 25 years: The International AIDS Society and its role in the global response to AIDS Pedro Cahn and Craig McClure* Address: International AIDS Society, 33, Chemin de ... dialogue, and to strengthen the focus on youth – began to be implemented in the planning for the XVI International AIDS Conferenc...

Ngày tải lên: 13/08/2014, 09:20

... circulating concentrations of TNF- α , IL-1 β , and IL-6 increase significantly in the early, hyperdynamic stage of sepsis and remain elevated in the late, hypodynamic stage of sepsis [27,49]. In ... Carayon P, Lejeune PJ: Role of extracellular molecular chaperones in the folding of oxidized proteins. Refolding of colloidal thyroglobulin by protein disulfide...

Ngày tải lên: 13/08/2014, 11:22

... clear. Basel level of transamidating TG2 activity was detected in Chinese-hamster MECHANISM OF TISSUE TRANSGLUTAMINASE UPREGULATION AND ITS ROLE IN OVARIAN CANCER METASTASIS Liyun Cao ... Figure 33 Wild-type TG2 and N-terminal fibronectin binding domain of TG2 induce EMT in OV90 cells 104 Figure 34 Wild-type TG2 and N-terminal fibronecti...

Ngày tải lên: 24/08/2014, 10:58

... during ER stress 23 9. The role of eIF2~ P in disease 28 10. CHOP plays a critical role in eIF2~ P-induced stress responses 30 11. Role of CHOP in apoptosis induced by ER stress 32 MATERIALS AND ... PERK protein kinase phosphorylates the α subunit of eIF2 at serine 51. Phosphorylation of eIF2 elicits global translation repression, reducing the influx...

Ngày tải lên: 24/08/2014, 12:32

Ngày tải lên: 14/11/2014, 06:30