... effect of HSF4 onchromatin. In the absence of HSF4, histone H3K9methylation is induced and HSF1 binding is reduced,indicating that HSF4 facilitates HSF1 binding viachromatin remodelling. Heat shock ... 4151 113 Trinklein ND, Chen WC, Kingston RE & Myers RM(2004) Transcriptional regulation and binding of heat shock factor 1 and heat shock factor 2 to 32 human heat shock genes during thermal ... section and scheme of the coronal section at E14.5 in (F). (A) At E11.5, HSF2 is expressed in forebrain, midbrain and in hindbrain except for the midbrain, hindbrain midline. Surprisingly, the...