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EFFECT OF CORONARY PERIVASCULAR ADIPOSE TISSUE ON VASCULAR SMOOTH MUSCLE FUNCTION IN METABOLIC SYNDROME

EFFECT OF CORONARY PERIVASCULAR ADIPOSE TISSUE ON VASCULAR SMOOTH MUSCLE FUNCTION IN METABOLIC SYNDROME

EFFECT OF CORONARY PERIVASCULAR ADIPOSE TISSUE ON VASCULAR SMOOTH MUSCLE FUNCTION IN METABOLIC SYNDROME

... Coronary Artery Disease 5 Coronary Microvascular Dysfunction in Metabolic Syndrome 7 Coronary Macrovascular Dysfunction in Metabolic Syndrome 8 Adipose Tissue, Distribution and Inflammation ... normal vascular function of PVAT (Figure 1.8). v ABSTRACT Meredith Kohr Owen EFFECT OF CORONARY PERIVASCULAR ADIPOSE TISSUE ON VASCULAR SMOOTH MUSCLE FUNCTION IN METABOLIC SYNDROME ... 11 Perivascular Adipose Tissue 16 PVAT in obesity 20 Coronary PVAT 25 Proposed Experimental Aims 28 Chapter 2: Perivascular adipose tissue potentiates contraction of coronary vascular smooth...
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Tài liệu Báo cáo Y học: Toxicity of substrate-bound amyloid peptides on vascular smooth muscle cells is enhanced by homocysteine docx

Tài liệu Báo cáo Y học: Toxicity of substrate-bound amyloid peptides on vascular smooth muscle cells is enhanced by homocysteine docx

... degeneration. In summary, the use of substrate-bound amyloid peptidesto study the effect of CAA on VSMC function provides anew approach to investigate the mechanisms of smooth muscle cell loss in vascular ... activation occurs in the presence of Ab, and caspase-3 levels are further increased in the presence of homocysteine.DISCUSSIONInCAA,Ab deposition occurs principally in associationwith the vascular ... on plastic alone, indicating that cell–substrate adhesion may beimportant in maintaining cell viability. Ab also caused anincrease in the number of apoptotic cells. This increase in apoptosis...
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báo cáo hóa học:

báo cáo hóa học:" The effect of newer anti-rheumatic drugs on osteogenic cell proliferation: an in-vitro study" doc

... investi-gate the effect of a COX-2 inhibitor on bone healing but on osteoblast proliferation in vitro. Osteoblast proliferation isonly one of the many processes involved in fracture healing.Our study ... In this case, administering Etoricoxib negated the effect of Dexamethasone on proliferation.Drugs with a varying (donor-dependent) effect One drug (Dexamethasone) had a significant varying effect ... significant vary-ing interaction effect (Table 4). On average, theinteraction effect was negative (administering Etoricoxibincreased the negative effect of Leflunomide on prolifera-tion). There...
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Báo cáo khoa học:

Báo cáo khoa học: "Effect of edging and docking methods on volume and grade recoveries in the simulated production of flitches" pps

... combinations of edging and trimminglines; 2) evaluate grade and volume yieldedby each edging and trimming line combina-tion; and 3) select the combination of edgingand ... flitch. In the following extract, the term’trimming’ is equivalent to ’docking’; and’cutting-line combinations’ refers to the com-binations of edging and docking lines." ... y co-ordinates of flitch;Fzmax,Fzmin: minimum and maximum z co-ordinates of flitch;lmin: minimum grading length;zj,k: z coordinate of kth docking sawline andjth:...
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Báo cáo y học:

Báo cáo y học: "Effect of increasing intraperitoneal infusion rates on bupropion hydrochloride-induced seizures in mice" pptx

... HCl-induced convulsions and on odds of convulsing vs not convulsing in miceGroup* Intraperitoneal (IP) infusion time (min)Time to Onset of Convulsions for Individual Mice (min)†Reduction in ... increase in infusion time resulted in further reduction in the odds of convulsions to 99.8% reduction at 240min.Conclusion: In conclusion, the demonstration of an inverse relationship between infusion ... administration of bupropion HCl 120 mg/kg bybolus injection induced convulsions in 6 out of 10 mice(60% of convulsing mice) in group 1. Increasing the totaltime of IP infusion of bupropion...
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Báo cáo y học: The effects of interleukin-8 on airway smooth muscle contraction in cystic fibrosis

Báo cáo y học: The effects of interleukin-8 on airway smooth muscle contraction in cystic fibrosis" pot

... the proliferation andmigration of rat vascular smooth muscle [22,23]. IL-8inhalation provokes bronchoconstriction in guinea pigs in vivo [24]. As IL-8 is increased in the airways of CFpatients ... A, Tkachuk V: The chemotacticaction of urokinase on smooth muscle cells is dependent on its kringle domain. Characterization of interactions and con-tribution to chemotaxis. J Biol Chem 2000, ... resulted in greater phosphorylation of myosin light chain (MLC20) in CF than in control cells. In addition, MLC20 expression was alsoincreased in CF cells. Exposure to IL-8 induced migration and...
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CONTRIBUTION OF PERIVASCULAR ADIPOSE TISSUE TO CORONARY VASCULAR DYSFUNCTION

CONTRIBUTION OF PERIVASCULAR ADIPOSE TISSUE TO CORONARY VASCULAR DYSFUNCTION

... 1-12 Perivascular adipose tissue and coronary atherosclerosis. Schematic representation of the proposed contribution of perivascular adipose tissue to coronary artery dysfunction and disease. Perivascular ... 1-12 Perivascular adipose tissue and coronary atherosclerosis. Schematic representation of the proposed contribution of perivascular adipose tissue to coronary artery dysfunction and disease. Perivascular ... expression in the coronary PVAT of MetS Swine. Immunohistochemistry of coronary artery cross sections displayed no evidence of leptin staining in lean swine (data not shown). In contrast, leptin staining...
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Báo cáo hóa học:

Báo cáo hóa học: " The effect of red blood cell transfusion on tissue oxygenation and microcirculation in severe septic patients" pdf

... transfusion in severe septic patients on sublingual microvascular perfusion and flow using SDFand on muscle tissue oxygenation, oxygen consumption ,and microvascular reactivity using NIRS. A secondaryobjective ... animprovement in sublingual microvascular perfusion in patients with altered perfusion at baseline and deteriora-tion in sublingual microvascular perfusion in patientswith preserved baseline perfusion ... hyperemia as a surrogate of micro- vascular functionality.ConclusionsThe effects of RBC transfusions on microvascular oxyge-nation, consumption, reactivity, perfusion, and flow arequite variable...
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Báo cáo y học:

Báo cáo y học: "The effect of voluntary fasting and dehydration on flicker-induced retinal vascular dilation in a healthy individual: a case report" doc

... dehydration and/or fasting is also capable of alter-ing vascular dynamics and BP [13]. Indeed, Alghadyan etal. [14] found a significant increase in onset of retinal veinocclusion (RVO) during fasting, ... (NO), arginine and glucose also inter-vene by regulating smooth muscle cell relaxation, andhence vascular dilation [1,8,9].The vascular response to flickering light has been widelystudied in both ... dilation in both the artery andthe vein during fasting and normal conditions (called the'reaction time') was calculated.The results of the initial measurements under fasting con-ditions...
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Báo cáo khoa học:

Báo cáo khoa học: " Effect of the medical emergency team on long-term mortality following major surgery"

... pre-existing con-ditions [2].ConclusionSevere large scale soft -tissue damage, including high-levelcontamination, was common to all tsunami victims repatriatedfrom the disaster area. During the interim ... glycopeptides only, and Stenotropho-monas maltophilia, sensitive to ofloxacin only. Polymicrobialwound contamination also included contamination with fungi(for instance, Candida albicans as well as non-albicans ... tractTsunami near-drowning involved the aspiration of immersionfluids as well as marine and soil debris into the respiratorytract, thus producing intrapulmonary inoculation of bacteria. In accordance,...
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