THE HAND1 LINEAGE REVEALS DISTINCT ROLES FOR HAND FACTORS DURING CARDIOVASCULAR DEVELOPMENT
Báo cáo khoa học: Identification of alternative promoter usage for the matrix Gla protein gene Evidence for differential expression during early development in Xenopus laevis doc
... necessary nuclear factors that are functional during early development. Evidence for developmentally regulated alternative promoter usage in the X. laevis MGP gene During early development, X. ... differential promoter usage in vivo. These findings indicate that transcription of the larger IA form is important for gastrulation, whereas the shorter IB form is likely to play a...
Ngày tải lên: 30/03/2014, 16:20
Báo cáo y học: " The Opossum genome reveals further evidence for regulatory evolution in mammalian diversification" doc
... be absent from the opossum. On the other hand, they estimate that around 20% of the noncoding elements conserved among eutherians are absent from the opossum. However, some of these elements ... evolved within the lineage leading to the placentals after its split with the marsupial lineage. Although the uniqueness of these sequences among dogs, humans and mice, with no evi...
Ngày tải lên: 14/08/2014, 08:20
báo cáo khoa học: " The first set of EST resource for gene discovery and marker development in pigeonpea (Cajanus cajan L.)" ppsx
... script. The Primer3 programme [77] was used for designing the primer pairs for SSRs and custom synthesized by MWG (MWG-Biotech AG, Bangalore, India). The primer pairs for SSRs were tested for their ... relatedness among the forty elite pigeonpea genotypes representing 8 wild species and 32 cultivated genotypes. The scale at the bottom of the dendrogram indicates the le...
Ngày tải lên: 12/08/2014, 03:21
Báo cáo y học: "Serum-dependent transcriptional networks identify distinct functional roles for H-Ras and N-Ras during initial stages of the cell cycle" doc
... functional roles for H-Ras and N- Ras in mammalian fibroblast cells. The global functional analyses were further complemented and reinforced by the study of the functional annotations of the individual ... properly cited. Ras isoforms and the cell cycle<p>Transcriptional and functional analysis reveals that the H-Ras and N-Ras isoforms have different roles in the i...
Ngày tải lên: 09/08/2014, 20:20
Báo cáo khoa học: Structural and functional roles for b-strand 7 in the a-crystallin domain of p26, a polydisperse small heat shock protein from Artemia franciscana pdf
... 10 : 1 for ovotransferrin, with the ratio rising as the molecular mass of the substrate increases [58]. For human aB-crystallin, the ratio is 1 : 1 [48]. The p26 chaperone activity therefore approximates ... nm. The A 360 values were multiplied by 1000 for construction of the curves. The standard error ranged from 4.2 to 7.0%. (D) Citrate synthase at 150 n M was heated a...
Ngày tải lên: 07/03/2014, 12:20
Báo cáo khoa học: Pleiotropy of leptin receptor signalling is defined by distinct roles of the intracellular tyrosines docx
... plasmid encoding either the short (LEPRa) or the long splicing variant (LEPRb) of the leptin receptor or were not transfected. Cells were serum-starved for 22 h and stimulated with the indicated cytokine ... to the Src SH2 domain: crystal struc- tures of the complexed and peptide-free forms. Cell 72, 779–790. 56 Demoulin JB, Van Roost E, Stevens M, Groner B & Renauld JC (199...
Ngày tải lên: 07/03/2014, 16:20
Báo cáo khoa học: Distinct but critical roles for integrin aIIbb3 in platelet lamellipodia formation on fibrinogen, collagen-related peptide and thrombin pot
... monolayer, even though they bind to distinct classes of surface receptor. This raises the ques- tion of the molecular basis of adhesion to these ligands and whether they induce distinct patterns of ... However, the requirement for signalling by the integrin on fibrinogen can be bypassed by the addition of thrombin to the solution. These observations reveal a critical role fo...
Ngày tải lên: 16/03/2014, 12:20
Báo cáo khóa học: Vertical-scanning mutagenesis of amino acids in a model N-myristoylation motif reveals the major amino-terminal sequence requirements for protein N-myristoylation ppt
... As there is no Met residue in the mature domain of TNF, this result indicates that the upper band corresponds to the protein species retaining the initiating Met residue and the lower band to the ... determine whether the remarkable change in the amino acid requirement at position 3 was specific for Ser or not, the Ala at position 6 in MG3X6 A-TNF was changed to other amino...
Ngày tải lên: 16/03/2014, 16:20
báo cáo hóa học: " Microglia use multiple mechanisms to mediate interactions with vitronectin; non-essential roles for the highly-expressed avb3 and avb5 integrins" pptx
... to drafting the manuscript. UT performed the flow cytometry and contributed to drafting the manuscript. RM conceived of the study, performed the biochemical analysis, and drafted the manuscript. All ... phagocytic processes in other cell types, the purpose of the current study was to investigate the contribution of these two integrins in this process, and thereby test our hy...
Ngày tải lên: 19/06/2014, 22:20
báo cáo khoa học: "Helping hands: A cluster randomised trial to evaluate the effectiveness of two different strategies for promoting hand hygiene in hospital nurses" ppsx
... understanding the indications for hand hygiene during patient care. They will also lea rn to apply the observation method and to use the data col- lection form. Before conducting the observation ... instruments. The primary effect parameter for this study is the per- centage of opportunities at which hand hygiene is per- formed by the nurses according to the National...
Ngày tải lên: 10/08/2014, 11:20