Báo cáo y học: "Methods for analyzing deep sequencing expres

Báo cáo y học: "Methods for analyzing deep sequencing expression data: constructing the human and mouse promoterome with deepCAGE data" ppt

... in the expression for the variance. Therefore, we use the raw tag- counts n and m in the expression for the variance. That is, the probability takes the form: () ! 2 (/ ) 2 2 e y N n n e n ynN n Ne y − ≈ −− () ⎛ ⎝ ⎜ ⎞ ⎠ ⎟ exp ... genome-wide in mouse and human across a variety of tissues and conditions. In the first part of the results we present the...

Ngày tải lên : 14/08/2014, 21:20

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Báo cáo khoa học: Initiation of JC virus DNA replication in vitro by human and mouse DNA polymerase a-primase ppt

... ﬁrmly established that the species speciﬁcity of lytic infection by the polyomaviruses SV40 and PyV is determined at the level of DNA replication both in vivo and in vitro by the nature of the ... a plasmid carrying the JCV origin. Columns 2 and 3, SV40 Tag with human and murine DNA polymerase a-primase, respectively; columns 4 and 5, JCV Tag with human and mur...

Ngày tải lên : 17/03/2014, 03:20

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Báo cáo y học: "Receptor for advanced glycation end products Glycine 82 Serine polymorphism and risk of cardiovascular events in rheumatoid arthritis" potx

... history, risk factors and their treatment, and details of RA and were clinically evaluated, with chart review for CV history, at least once. The study pro- tocol was approved by the Princess Alexandra ... laboratory analysis and radiographs. DNA was typed for HLA–DRB1 genes and RAGE Gly82→Ser polymorphism. The RAGE Ser82 allele, which is in linkage disequilibrium with...

Ngày tải lên : 09/08/2014, 10:20

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Báo cáo y học: "A double blind, randomized, placebo controlled study of the efficacy and safety of 5-Loxin® for treatment of osteoarthritis of the knee" potx

... 300 (Human, Wies- baden, Germany) and the haematological counter Humacount (Human) , respectively. The urine analysis was carried out by microscopy and by using UroColor™10 Dip Sticks (Standard Diagnostics, ... properties by inhibiting the 5-lipoxygenase enzyme. A 90-day, double-blind, randomized, placebo-controlled study was conducted to evaluate the efficacy and safety of 5-L...

Ngày tải lên : 09/08/2014, 10:23

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Báo cáo y học: "Predictors for pathologically confirmed aortitis after resection of the ascending aorta: A 12-year Danish nationwide population-based cross-sectional study" pdf

... conceived and designed the study, analyzed the data, performed the statistical analysis, and wrote the draft manuscript. KS and JK participated in designing the study, and in analyzing the data. ... closely associated with aortitis or aortic aneurysm (5 with previously diagnosed temporal arteri- tis, 1 with Crohn’s disease, 1 with rheumatoid arthritis, 1 with s...

Ngày tải lên : 12/08/2014, 15:23

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Báo cáo y học: " Allowing for spontaneous breathing during high-frequency oscillation: the key for final success" pptx

... to reduce the imposed work of breathing, may therefore increase patient comfort, and should theoretically allow for maintaining spontaneous breathing while heavy sedation and muscular paralysis could ... application. With the recognition of the role of ventilator-induced lung injury in the morbidity and mortality of patients with acute lung injury, there has also been incr...

Ngày tải lên : 13/08/2014, 01:20

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Báo cáo y học: "Genome-wide identification of novel expression signatures reveal distinct patterns and prevalence of binding motifs for p53, nuclear factor-κB and other signal transcription factors in head and neck squamous cell carcinoma" docx

... microarray profiling and computational analyses is a powerful way to identify gene signatures as determinants for cancer heterogenicity and malignant phenotypes, and their underlying regulatory con- trol ... kindly provided by Drs Thomas E Carey and Carol R Bradford, and some information was previously presented in the literature. 'Primary sites' refers to the origi...

Ngày tải lên : 14/08/2014, 07:21

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Báo cáo Y học: Propionate CoA-transferase from Clostridium propionicum Cloning of the gene and identi®cation of glutamate 324 at the active site pdf

... puri®ed and the gene encoding the enzyme has been cloned and sequenced. The enzyme was rapidly and irre- versibly inactivated by sodium borohydride o r h ydroxyl- amine in the presence of propionyl-CoA. ... cultures (DSMZ, Braunsc hweig, Germany). Synthesis of acyl-CoA substrates Acetyl-, butyryl- and propionyl-CoA were prepared from the corresponding anhyd rides and CoA b...

Ngày tải lên : 17/03/2014, 17:20

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Báo cáo Y học: Extra terminal residues have a profound effect on the folding and solubility of a Plasmodium falciparum sexual stage-speciﬁc protein over-expressed in Escherichia coli pptx

... MBP and other fusion protein expression systems have been widely used, both because the fusions serve as efﬁcient puriﬁcation tags and because they are able to promote the solubility of the fused ... Hopkins University Bloomberg School of Public Health, Baltimore, Maryland, USA The presence of extra N- and C- terminal residues can play a major role in the stability, solubili...

Ngày tải lên : 23/03/2014, 21:20

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Báo cáo y học: "Peroxisome proliferator-activated receptor γ1 expression is diminished in human osteoarthritic cartilage and is downregulated by interleukin-1β in articular chondrocytes" doc

... number not for citation purposes) chondrocytes were pretreated for 30 minutes with selective inhibitors for the above pathways, and then stimulated or not with IL-1 for 18 hours. Total cell lysates ... understanding of the patho- physiology of OA. Conclusion The decreased expression of PPARγ in OA cartilage and the literature supporting a protective role for PPARγ...

Ngày tải lên : 09/08/2014, 10:20

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