Báo cáo sinh học: "Developmental time at which spontaneous, X-ray-induced and EMS-induced recessive lethal mutations become effective in Drosophila melanogaster" potx

... that lethal mutations extracted from natural populations become effective considerably later on the average than X-ray- and ENTS-induced lethal mutations. Since natural mutations ... spontaneous and natural lethal mutations, X-ray induced lethal mutations and EMS-induced lethal mutations has taken advantage of these new technical possibil...

Ngày tải lên: 14/08/2014, 20:20

... of bombesin receptor in most adult and pediatric human glioblastoma cell lines; role in mitogenesis and in stimulating the mitogen-activated protein kinase pathway. Mol Cell Endocrinol 1997; ... overexpressing the GRP receptor such as breast cancer and prostate carcinoma [6–13, 40–41]. Integrins play a key role in angiogenesis and tumor metastasis by mediating tumor ce...

Ngày tải lên: 18/06/2014, 18:20

... have demonstrated that the BLV promoter transactivation and immortalization activities of wild-type Tax can be dissoci- ated by mutations within specific regions of the protein [9]. In fact, phosphorylation ... serines 106 and 293 are required for in vitro cell transformation but not BLV LTR transactivation [34]. Tax transcriptional activity requires an amino-terminal zinc finger a...

Ngày tải lên: 14/08/2014, 19:22

... enumerate candidates of the matches by dividing the query into k +1substrings and finding the exact matches of these divided sub- strings, as at least one of the divided substrings must exactly match ... finding R (i.e., ˆ R (S, T)) that minimizes  E R (S, T)= ||   sRt ii i n    2 1 , by trans- lating both S and T so that both of their centroids are moved to the origin of the coo...

Ngày tải lên: 12/08/2014, 17:20

... [3]. The retinol binding protein 4 (RBP4) gene codes for a member of the RBP protein family present in the uterus and in embryos during the early stages of gestation [4]. These proteins bind retinol, ... or maternal imprinting: used in the analy- sis of IGF2 SNP. Two association analyses were per- formed fitting the paternal imprinting effects. Additive and dominant effects were in...

Ngày tải lên: 14/08/2014, 13:21

... transcription rate is an intrinsic property of its 5’ inverted repeat. Another mechanism which could explain a relationship between the breeding temperature and an excision rate would ... been investigated in many ways (Hoffmann and Parsons, 1991), and often by considering the mutator effect of various chemicals and radiations. In this cont...

Ngày tải lên: 14/08/2014, 19:22

... replicated heterochromatin. Also, chromatin remodeling regulates the binding of superordinate chromatin proteins, as indicated by the observation that the human cohesin protein hRAD21, which ... also its acetylation state impinges upon replication initiation. In S. cerevisiae, chromatin acetylation regulates the time point during S-phase at which an origin initiates replication. Del...

Ngày tải lên: 16/03/2014, 16:20

... managers interviewed were in favour of Agenda for Change, believing that, in part at least, it would assist in delivering the improvements in patient care and staff experience that were its stated ... through analysis of national level data and information on costs and impact; and thirdly to assess the relevance and effectiveness of any systematic evaluation of impact that...

Ngày tải lên: 18/06/2014, 17:20

... recruit and re-engage qualified Malawian staff. • Expanding domestic training capacity, including dou- bling the number of nurses and tripling the number of doctors in training. • Using international ... prescribing and dispens- ing, and to train and equip HSAs with the competencies to provide ART drugs; keep accurate patient records; and question carers and patients so that a...

Ngày tải lên: 18/06/2014, 17:20

... recommend system- atic sharing of experiences across and within countries in planning and implementation of different types of HRH data collection, both routine and periodic in nature, in order to ... descriptive statistics on a number of policy-rele- vant indicators for monitoring and evaluation of HRH, including skill mix, age and sex distribution, educational attainment, in...

Ngày tải lên: 18/06/2014, 17:20