Báo cáo sinh học: " HCV entry receptors as potential targets for siRNA-based inhibition of HCV" ppt

... interference expression cassettes. Mol Ther 2006, 14:485-493. doi:10.1186/1479-0556-9-15 Cite this article as: Jahan et al.: HCV entry receptors as potential targets for siRNA-based inhibition of HCV. Genetic ... inhibition of HCV entry via cellular receptors using siRNA against CD81, LDLR, SR- BI, CLDN1 was observed, which we interpreted as con- firmation o...

Ngày tải lên: 14/08/2014, 19:23

... responsible for maintaining the tumor and, possibly, for the formation of new tumors at metastatic loci. CD44 has been identified as an important marker of such a population of cancer stem cells in breast, ... overexpression of variant, high- molecular-mass isoforms CD44v4–v7 and CD44v6–v9 in various cancers [45–52], as well as the downregula- tion of the CD44s isoform in c...

Ngày tải lên: 28/03/2014, 23:20

... non-cell based alternative for using MSC in treatment of cardiovascular disease [23]. Non-cell based therapies as opposed to cell-based therapies are generally easier to manufacture and are safer as ... the cells started to form clusters instead of adhering to the plastic dish as a monolayer. The surface antigen profile of the MYC-transformed cells was quite similar to that of...

Ngày tải lên: 18/06/2014, 19:20

... dataset, it is ten-class classification). The classifying process was carried out for each dataset. 4 Half of the target images were used for training and the rest for testing. Caltech consists of ... preparation for the experiments, object areas were clipped from the images as target images using the object area information available in the dataset, because these datasets do not...

Ngày tải lên: 21/06/2014, 16:20

... the NIRS 2 v. 4.11 software package (InfraSoft International). A 16/32 sequence (16 measurements of the reference ceramic then 32 measurements of the sample) was obtained for each sample. The ... of the commer - cial height. 2.2. Sampling method Two sets of measurements were performed: (a) On each tree, a disk was taken for chemical analysis at half of the commercial height. A t...

Ngày tải lên: 08/08/2014, 14:20

... production of sexuals until they have reached a critical worker number at which t he efficient production of large numbers of sex- ual offspring has become feasible [5,8]. In analogy, metastasis is often ... understood as an issue of labor optimization: A) A non-social organism has no choice when addressing a task but to perform it as an unbroken series of steps. B) A colony can...

Ngày tải lên: 18/06/2014, 19:20

... inoculation of neonatal mice with MoFe2 resulted in the development of T-cell lymphoma. Analysis of patterns of common proviral insertion in lymphomas revealed that MoFe2 utilized a set of CISs distinct ... from which it was constructed [39,40]. Sequence surrounding one of the previously described CISs in MoFe2-induced lymphomas, termed MF8T (Rasgrp1), was analyzed for the prese...

Ngày tải lên: 19/06/2014, 08:20

... regulatory subsets, was directly responsible for the development not only of immune deficiency, but also of activation. As a result of the expression pattern of their receptors/ co- receptors [13-15], ... by Kim Hasenkrug, Laboratory of Persistent Viral Diseases, Rocky Mountain Laboratories, NIAID, NIH, Hamilton, USA) was free of lactate dehydro- genase-elevating virus and...

Ngày tải lên: 06/08/2014, 19:21

... increased and decreased numbers, perhaps because of different assays used to measure the size of this compartment. Furthermore, in correlating disease progression with Tregs, the measure of ... Increased incorporation of RTEs into naïve pool Increased death (DTA-mediated) Increased division Increased entry into memory pool Size of naïve CD4 + T cell pool unchanged (in presence...

Ngày tải lên: 06/08/2014, 19:21

... was involved in transcriptional elongation. o2 was then identified as a high-copy- number suppressor of hpr1∆. Yeast tho2∆ mutants also showed a strong hyper-recombination phenotype that was ... seen as just a side effect of the physiological consequences of THO mutations, but it turned out to reveal a role for THO in forming an optimal mRNP particle, one that prevents the n...

Ngày tải lên: 06/08/2014, 19:21