... observed in 29clones (21.5%) out of 135 clones sequenced. In order toincrease the sample size and to investigate the extent of amino acid substitution in the E protein, the deducedamino acid ... nucleotides in length covering 413 amino acids which included 40amino acids at the N terminal end of NS1 protein, the NS3region was 866 nucleotides in length covering 288 aminoacids, and the NS5 ... spectra in structural proteins thannon-structural proteins probably imply less genetic con-straint on the structure proteins to maintain proper func-tion than non-structural proteins. However, the mutations...