Báo cáo y học: "Phylogenetically widespread alternative splicing at unusual GYNGYN donors" pot
Báo cáo y học: "Phylogenetically widespread alternative splicing at unusual GYNGYN donors" pot
... the original work is properly cited. GYNGYN alternative splicing& lt;p>Computational and experimental evidence is given for alternative splicing at the unusual GYNGYN motif in several species, ... report the occurrence of alternative splicing at GYNGYN tandem donors in six other animals and a plant. Analyzing the GYNGYN motifs that do and do not allow alternative...
Ngày tải lên: 14/08/2014, 17:22
Báo cáo y học: "Analysis of alternative splicing with microarrays: successes and challenges" docx
... indicated that about half of these represented genuine alternative- splicing events. This work [18] clearly demonstrates that microarrays can detect alternative splicing, but many types of alternative splicing ... into account the rate of validation by RT-PCR, this means that alternative splicing has been discovered in nearly 800 genes that were not previ- ously known to be alte...
Ngày tải lên: 09/08/2014, 20:20
Báo cáo y học: "Variation in alternative splicing across human tissues" potx
... 3 ACTTTCATCCTGGGCTGTGCTCCCTGCAATGTGATCTGCTCCGTTGTTTTCCAG ACATTCATTCTGAGCTGTGCTCCATGCAATGTCATCTGCTCCATTATTTTCCAG E4a GATCGTTTTGATTATAAGGATAAAGATTTTCTTATGCTCATGGAAAAACTAAAT AAACGATTTGATTATAAAGATCAGAATTTTCTCACCCTGATGAAAAGATTCAAT E4b ... Bork P: Alternative splicing and genome complexity. Nat Genet 2002, 30:29-30. 32. Lee CJ, Irizarry K: Alternative splicing in the nervous system: an em...
Ngày tải lên: 14/08/2014, 14:21
Báo cáo y học: " Divergence of exonic splicing elements after gene duplication and the impact on gene structures" pot
... study proposed a model of alternative splicing evo- lution relevant to duplicated genes. The model depicts that alternative splicing isoforms are lost rapidly after gene dupli- cation at an early ... two types of regula- tory elements that are currently the best annotated. Using the synonymous substitution rate (Ks) between duplicates as a proxy for time after gene duplication, we f...
Ngày tải lên: 09/08/2014, 20:20
Báo cáo y học: "Impairment of alternative splice sites defining a novel gammaretroviral exon within gag modifies the oncogenic properties of Akv murine leukemia virus" pdf
... GAT AAAGAG GTAGGAA CCTCTGATCTATATAACTGGAAAAATAATAATCCTTCCTTCTCTGAG GAT AAAGAG GTAGGAA CCTCTGATCTATATAACTGGAAAAATAATAATCCTTCCTTCTCTGAG GAT AAAGG G GAC GAAA CCAGCGATCTATATAACTGGAAAAATAATAATCCATCATTCAGTGAA ... indi- cated by a vertical line. The boldfaced A in the sequence indi- cates the presumed branch point. SA’- consensus: CTRAYY YYYYYYYYNCAG|G Akv: TTTTCCTCCTCTGATCTATATAACTGGAAAAATAATAATCCT...
Ngày tải lên: 13/08/2014, 05:22
Báo cáo Y học: Importin a binds to an unusual bipartite nuclear localization signal in the heterogeneous ribonucleoprotein type I pptx
... clearly visible within the nuclei in cells were the plasma membrane was permeabilized by digitonin, followed by incubation at 30 °Cfor45minwith rabbit reticulocyte lysate and an ATP energy-regenerating system ... brain-enriched polypyrimidine tract- binding protein antagonizes the ability of Nova to regulate neu- ron-specific alternative splicing. Proc.NatlAcad.Sci.USA97, 6350–6355. 41. M...
Ngày tải lên: 18/03/2014, 01:20
Báo cáo Y học: The presence of phosphate at a catalytic site suppresses the formation of the MgADP-inhibited form of F1-ATPase potx
... previously reported th at the DNC a 3 b 3 c sub com - plex did not exhibit steady-state ATP hydrolysis in the absence o f P i [16], but signi®cant steady-state ATP hydro- lysis was later observed ... substrate or product at catalytic sites in different conformations has been suggested by Boyer [42]. At higher ATP concentrations, the effect of P i on the ATP- binding rate was not observe...
Ngày tải lên: 24/03/2014, 00:21
Báo cáo Y học: Environmentally coupled hydrogen tunneling Linking catalysis to dynamics potx
... incorporate features of hydrogen transfers that Eqn (2) neglects, but at the expense of a bit more complexity. What is the significance of hydrogen-atom tunneling? Many metallo-enzymes that activate ... over, the barrier may dominate the reaction pathway. SLO catalyzes the production of fatty acid hydroper- oxides at 1,4-pentadienyl positions, and the product 13-(S)- hydroperoxy-9,11-(Z,E)...
Ngày tải lên: 31/03/2014, 23:20
Báo cáo y học: " A Novel Population of Mesenchymal Progenitors with Hematopoietic Potential Originated from CD14- Peripheral Blood Mononuclear Cell" potx
... University, Xi'an, 710032, China 3. Department of Oral Histology and Pathology, School of Stomatology, Fourth Military Medical University, Xi’an, 710032, China 4. Department of Stomatology, ... with hematopoietic potential. Herein, we identified a novel CD14 - cell-derived population with both mesenchymal and hematopoietic features in rat peripheral blood, and this cell population...
Ngày tải lên: 08/08/2014, 18:20
Báo cáo y học: Advances in the Surgical Management of Chronic Rhinosinusitis" pot
... Can Predispose Patient to Chronic Rhinosinusitis Concha bullosa (pneumatized middle turbinate) Paradoxically curved middle turbinate Atelectatic uncinate process Infraorbital ethmoid pneumatization (Haller’s ... therefore in the patient’s sinuses). The basic process involved is that of correlation between patients’ actual bony anatomy and their preoperative CT scans, which is performed by sop...
Ngày tải lên: 08/08/2014, 20:23