Báo cáo sinh học: "Fine mapping and replication of QTL in outbred chicken advanced intercross lines" potx

... 5 of 10 RESEARCH Open Access Fine mapping and replication of QTL in outbred chicken advanced intercross lines Francois Besnier 1* , Per Wahlberg 2 , Lars Rönnegård 3 , Weronica Ek 1 , Leif Andersson 1,2 , ... refine original QTL findings and dissect the genetics underlying complex phenotypes. Replicating the detection of the QTL and fine -mapping their locatio...

Ngày tải lên: 14/08/2014, 13:21

... strengths of fine mapping and backcrossing and paves the way for introgression of desirable but unknown QTL into recipient animal and plant lines [5]. Combining QTL identification and introgression ... unknown QTL into recipient animal and plant lines. Methods: The method consisting in combining QTL mapping and gene introgression has been extended from inbred to...

Ngày tải lên: 14/08/2014, 13:21

... surgery. Possible impact of changes in initial clinical training system Japan introduced a new clinical training system in 2004, and this will probably affect physicians' career choices in the future. ... working in high-risk spe- cialties are less satisfied [13,14] and more inclined to change jobs [15]. In Japan, HPs' working conditions, in terms of working hour...

Ngày tải lên: 18/06/2014, 17:20

... the private for profit sector and 21% the private not for profit sector. Of 186 students who preferred the public sector, 36% indicated the intention of combining a public sector job with work in the private ... burden of lecturing and learning hours demanded by the medical school. Twenty-six percent were unhappy or partially unhappy with it and 20% did not have any opinion. Reg...

Ngày tải lên: 18/06/2014, 17:20

... other incentives and support mechanisms (follow up visits, continuing training, mentoring ) affecting job satisfaction. Conclusion: Training increasing self confidence and self esteem of rural ... implications As the training consists to a large extent in compensating for shortcomings of the medical school-based training, a reasonable approach would be to incorporate this kind of...

Ngày tải lên: 18/06/2014, 17:20

... lists of public and private facilities in e ach district, using a random starting point and fixed selection interval. Doctors and nurses were selected at random from a list of all doctors and nurses usually ... [15]. The Joint Learning Initiative Report also highlights the importance of management culture and working condi- tions in affecting motivation, and cites small...

Ngày tải lên: 18/06/2014, 17:20

... view of the role of IFN-g producing T cells in protecting the host against cancers. For example, IFN-g was shown to promote immune editing and subsequent tumor escape in the CT26 colon carcinoma ... ligated into the expression vector pRSET (Invitrogen). The BL21 (DE3) pLysS strain of E. coli was used for the expression the proteins. Proteins were purified under denaturing con- dit...

Ngày tải lên: 18/06/2014, 19:20

... relating to low potency and cost. Peptide-based drug candidates are limited by insufficient efficacy and unfavorable phar- macokinetics. MAbs have increasingly gained favor in large part because of ... target- ing mRNA for degradation and indirectly inhibiting all viral RNA transcription. Proc Natl Acad Sci USA 2003, 100:2718-2723. 45. Gitlin L, Karelsky S, Andino R: Short interferi...

Ngày tải lên: 18/06/2014, 22:20

... problems relating to sensitivity of the HSV-1 and -2 probe relative binding. In a single step multiplex assay mutations in the probe binding area are reported to lead to a loss in sensi- tivity and error in ... effec- tiveness of any current intervention, determining the effi- cacy of drugs, assessing drug resistance and are useful research tools in the study of the ep...

Ngày tải lên: 19/06/2014, 08:20

... for interrogation of gene and protein function, including DNA microarrays for global gene-expression profiling and location of DNA-binding factors, and a comprehensive set of gene deletion strains ... Statistical enrichment of interaction pairs as a function of protein abundance for each indicated dataset. Protein or gene pairs were separated into bins representing increasing...

Ngày tải lên: 06/08/2014, 18:21