Báo cáo sinh học: "Mapping quantitative trait loci (QTL) in sheep II Meta-assembly and identification of novel QTL for milk production traits in sheep" docx

... entire pedigree including final offspring. This submatrix is then inverted, and contributions of final offspring, computed with known parental linkage phases, are added into the inverse. ... can be obtained by Gibbs sampling, which was implemented using blocking of the genotypes of parents and final offspring (finals) as in Janss et al (19...

Ngày tải lên: 09/08/2014, 18:22

... computation of the inverse of the variance-covariance matrix becomes approximate due to uncertain linkage phases in parents of final offspring, and other ways of computing this inverse ... mapping of polygene loci in livestock. Proc Int Biometric Soc (in press) in the simulation, and data sets were analyzed by ignoring relationships...

Ngày tải lên: 09/08/2014, 18:22

... identified in G 2 ani- mals) was developed and programmed using R [40] by one of us (PCT). The software allows easy modification for the identification of QTL for most types of traits, including binary ... 50°C for 1 min, 72°C for 1 min and a final 5 min extension at 72°C. The Cav-low cycles were as follows: initial denaturation for 5 min at 95°C, 5 cycles of 95...

Ngày tải lên: 14/08/2014, 13:21

... loci (QTL) in sheep. II. Meta-assembly and identification of novel QTL for milk production traits in sheep Herman W Raadsma*, Elisabeth Jonas, David McGill, Matthew Hobbs, Mary K Lam and Peter ... and confidence interval (where availa- Results of the QTL analysis using QTL- MLE for the single traits of the yields until day 100Figure 2 Results o...

Ngày tải lên: 14/08/2014, 13:21

... Hobbs M, Lam MK, Thomson PC: Mapping quantitative trait loci (QTL) in sheep. II. Meta-assembly and identification of novel QTL for milk production traits in sheep. Genet Sel Evol 2009, 41:45. 28. ... chromosome 14. For muscle traits, eight QTL were detected on seven chromosomes, for fat traits ten QTL on seven chromosomes and for bone traits...

Ngày tải lên: 14/08/2014, 13:21

... Hobbs M, Lam MK, Thomson PC: Mapping quantitative trait loci (QTL) in sheep. II. Meta-assembly and identification of novel QTL for milk production traits in sheep. Genet Sel Evol 2009, 41. 19. ... and milk composition traits in sheep, and to provide addi- tional information on QTL for these traits. The applica- tion of QTL information fo...

Ngày tải lên: 14/08/2014, 13:21

... construction and not omitted for any rea- son. QTL mapping analysis was initially performed using interval mapping as implemented in MapQTL version 5.0 [30]. Estimates of QTL position were obtained at ... Fernandez-Martinez JM, Berry ST: Mapping minor QTL for increased stearic acid content in sunflower seed oil. Mol Breeding 2004, 13:313-322. 30. van Ooijen JW: MapQTL ® 5.0...

Ngày tải lên: 12/08/2014, 03:21

... response and the origin of the ERAD and ESCRT systems. Background Post-translational modification of lysine, serine, threonine, tyrosine, aspartate, arginine and proline residues in proteins are ... A tandem affinity tag for two-step purifica- tion under fully denaturing conditions: application in ubiqui- tin profiling and protein complex identification combined with in...

Ngày tải lên: 14/08/2014, 21:20

... verified the infection and intracellular growth of L. pneumophila in A549 cells. Intracellular growth of the virulent strain was observed 1 day after infection, subse- quently increasing to approximately ... including L. pneumophila promotes the apoptosis of phagocytes, resulting in either control of intracellular growth of the bacteria or evasion of the immune system [14]....

Ngày tải lên: 12/08/2014, 15:21

... an adaptation of composite interval mapping to pedigree analysis. Gains in power from fitting additional unlinked QTL and selection of QTL to be included in the analysis ... recombination. Another reason is the small number of families differing in the flanking and next-to-flanking markers, resulting in too little information for esti...

Ngày tải lên: 09/08/2014, 18:22