Báo cáo y học: "Erect wing regulates synaptic growth in Drosophila by integration of multiple signaling pathway" pptx

... regulate synaptic growth. (a-d) Genetic interaction of ewg with known signaling pathways in synaptic growth regulation. Synaptic growth was analyzed at third instar NMJs by quantifying type 1b ... phenylalanine hydroxylase involved in dopamine and serotonin synthesis. Candidates for mediating the synaptic growth phenotype from the remaining Genes differentially regul...

Ngày tải lên: 14/08/2014, 08:21

... results in intrinsic tyrosine kinase receptor activity and the transduction of intracellular signaling pathways, including MAPK and PI3K pathways [2]. It is becoming evident that signaling pathways ... activation of adenylyl cyclase [5,6]. Multiple sclerosis (MS) is an inflammatory de- myelinating disease of the CNS characterized by infil- tration of macrophages and T-cell...

Ngày tải lên: 08/08/2014, 17:20

... the mean of at least three independent determinations. Cysteine and tryptophan were not determined. Hydroxyproline, hydroxylysine and phosphoserine were not detected in all samples. Amino acid Water-soluble matrix Water-insoluble matrix EDTA-soluble matrix EDTA-insoluble matrix Asx ... (EDTA-SM). Cysteine, hydroxylysine, hydroxy- proline, phosphoserine, proline and tryptophan were not det...

Ngày tải lên: 21/02/2014, 01:21

... phosphotyrosine binding pocket. The binding of the peptide F429pY431 thus involves a shift of two residues when compared to the binding mode of pY429pY431 with pY431 binding into the classical pY-binding ... phosphotyrosines bind to the phosphotyrosine binding pocket of the SH2 domain, with R94 only playing a minor role in the binding of these peptides. DISCUSSION The cytoplasmic...

Ngày tải lên: 24/03/2014, 00:21

... to B lymphocytes, FDCs, or the combination of B lymphocytes and FDCs at the initiation of cul- ture, and supernatants were harvested after 7 days of incubation. In keeping with the purity of our FDCs, ... adherent cells in culture and stained negatively for CD20 and CD3 and positively for CD14 and VLA-4 by flow cytometry (data not shown). In addition, viability testing indicat...

Ngày tải lên: 08/08/2014, 20:23

... as follows: day 1, 10 minutes at 10 m/min; day 2, 15 minutes at 12 m/min; day 3, 20 minutes at 15 m/min; day 4, 30 minutes at 18 m/min; and day 5, 35 minutes at 20 m/min. On day 8 and thereafter, the ... sharply 1 day after injection of chymopa- pain into the knee joint in rabbits [26]. The serum keratan sulfate also sharply decreased, and these changes were accompanied by depletion of...

Ngày tải lên: 09/08/2014, 10:22

... separated by the proximity of the cells to the joint space and the bone respectively, alignment of the chondrocytes along the arcades of Benninghoff [29] and by the appearance of hypertrophic cells. ... physes (two joints) and at least three sections per physis were analyzed by measuring the surface areas of 10 randomly chosen lacunae from each of three representative micros...

Ngày tải lên: 09/08/2014, 14:22

... family. Scores, P-values and family information are shown in Table S1 in Additional file 1. Our s ynteny- based scoring eliminates over 90% of the false positives corresponding to terminators of independent ... first in our list of genes most often regulated by attenuation (Figure 1). rimP,previously known as yhbC in E. coli and ylxS in B. subtilis, encodes a protein recentl...

Ngày tải lên: 09/08/2014, 22:23

... pre- viously [13]. Briefly, uracil -containing single-stranded DNA (ssDNA) was prepared by transforming pBKS-NIS- 5’ into E. coli CJ236 strain. Uracil-containing ss DNA was annealed with 5’-kinase ... antibody follo wed by enhanced chemiluminescence system (Amersham, Chal- font St. Giles, Buckinghamshire, UK) and exposed by autoradiography. Immunofluorescent staining HepG2 cells were se...

Ngày tải lên: 10/08/2014, 05:21

... cytology (FNAC) of the axillary lesion and core needle biopsy of the breast lesion. The FNAC was indeterminate (C3) but showed numerous monotonous lymphocytes in a background containin g lymphogranu- lar ... axillary lymph node biopsy. The results of a histological examination (Fig- ures 1 and 2) of the resected specimens of breast and axillary lesions were suggestive of an intr...

Ngày tải lên: 10/08/2014, 23:22