Báo cáo y học: " Prediction of synergistic transcription factors by function conservation" ppsx

... properly cited. Synergistic transcription factors& lt;p>A new strategy is proposed for identifying synergistic transcription factors by function conservation, leading to the identification of 51 ... its functional co- Table 4 Significance of E2F1 synergy for different distance constraints and sensitivity/specificity for detecting synergistic E2F1 combinations by fun...

Ngày tải lên: 14/08/2014, 08:20

... Thr70, the sites most profoundly affected by rapamycin, may be regulated by nutrients through the mTOR pathway. REGULATION OF 4E-BP1 BY AMINO ACIDS In a number of kinds of mammalian cells, amino ... the control of eIF4E (by 4E-BP1) for the activation of protein synthesis by amino acids [92]. In isolated rat heart cells (ventricular myocytes), protein synthesis is acutely ac...

Ngày tải lên: 23/03/2014, 21:20

... model of interaction can be tested b y additional mutations, by solving the structure of some of the complexes or by other experimental means. CONCLUSIONS We have analysed the possibility of predicting ... the probability of correct predictions [P(x) in Table 1]. P(x) gives the accuracy of the prediction of the x class with respect to the overall amount of total predic...

Ngày tải lên: 21/02/2014, 15:20

... depletion of glucose is accompanied by concerted changes in the mRNA levels for most enzymes of the central metabolism of yeast resulting in down-regulation of glycolysis and up-regulation of the ... glycolysis to the replenishment of the ethanol reservoir to make use of it in a later phase of starvation. Increasing activity in the lower part of glycolysis (E 2 ) enhances...

Ngày tải lên: 17/03/2014, 10:20

... 0.2 137 Cys 0.2 Cys 0.2 Cys 0.2 Cys 0.2 Cys 0.2 Cys 0.2 Cys 0.2 Cys 0.2 Cys 0.2 138 Cys 0.64 Cys 0.64 Cys 0.64 Cys 0.64 Cys 0.64 Cys 0.64 Cys 0.64 Cys 0.3 Cys 0.3 139 Cys 1.18 Cys 1.18 Cys 1.18 Cys ... 2.5 121 Cys 2.25 Cys 2.25 Cys 2.5 Cys 2.25 Cys 2.25 Cys 2.25 Cys 2.25 Cys 2.25 Cys 2.25 122 Lys 2 Lys 1.6 Lys 2.25 Lys 2 Lys 2 Lys 2 Lys 2 Lys 2 Lys 2 123 Thr 0.35 Ala 0.4 Asn 2 Thr 0.35 Thr .....

Ngày tải lên: 12/08/2014, 02:20

... classifier. The accuracy of the rules is measured by their support (relative frequency of the body or head of the rule) and confidence (conditional probability of the body given the head of the rule). ... feature selection by using relative Shanon entropy, comparative sequence logos, and viral epidemiology signature pattern analysis (VESPA) for positional enumeration of amino...

Ngày tải lên: 12/08/2014, 04:20

... dis- cover novel non-conserved microRNAs systematically missed by prediction methods which rely on evolutionary conservation of sequences. This proposed method employs Support Vector Machine trained ... entries respectively. The model correctly predicted 22 out of the 23, 11 out of 13 and 10/11 of the microRNAs expressed by EBV, KSHV and CMV respectively. The comparisons of di...

Ngày tải lên: 12/08/2014, 04:20

... phosphorylated by CDK2/cyclin E in vitro. A, Tat is phosphorylated by CDK2. Recombinant Tat was phosphorylated in vitro by purified CDK2/cyclin E (lane 1), by HeLa nuclear extract (lane 2) or by CDK2-depleted ... 99:387-402. Retrovirology 2006, 3:78 http://www.retrovirology.com/content/3/1/78 Page 4 of 21 (page number not for citation purposes) Analysis of HIV-1 Tat phosphoryla...

Ngày tải lên: 13/08/2014, 09:20

... assessed accord- ingly. SVI was calculated from cardiac output, measured by transpulmonary thermodilution divided by heart rate and body surface area. Study design and monitoring Hemodynamic and volumetric ... undergoing coronary bypass surgery. Anesthesiology 1994, 81:76-86. 17. Hinder F, Poelaert JI, Schmidt C, Hoeft A, Mollhoff T, Loick HM, Van Aken H: Assessment of cardiovascular vo...

Ngày tải lên: 13/08/2014, 10:20

... size. Secondly, we did not assess the impact of the mode of ventilation on other important goals of ICU care, namely ICU length of stay and mortality. Although this is the largest study to date ... trial because of the respiratory load imposed by the endotracheal tube, so varying levels of respiratory support are widely used during the trial. Automatic tube compensation (ATC), s...

Ngày tải lên: 13/08/2014, 15:21