Báo cáo y học: " The reticulons: a family of proteins with diverse function" pptx

... 160:224-235. 36. Iwahashi J, Kawasaki I, Kohara Y, Gengyo-Ando K, Mitani S, Ohshima Y, Hamada N, Hara K, Kashiwagi T, Toyoda T: Caenorhabditis elegans reticulon interacts with RME-1 during embryogene- sis. ... factor betaPIX. J Cell Biochem 2006, 99:1203-1215. 41. Wakana Y, Koyama S, Nakajima K, Hatsuzawa K, Nagahama M, Tani K, Hauri HP, Melancon P, Tagaya M: Reticulon 3 is involved in m...

Ngày tải lên: 14/08/2014, 08:20

... deaminases. CDA Bacteria, archea yeast, plants, metazoans DCDT Gram+ bacteria, archea, yeast, plants, metazoans, viruses Tad/ADAT2 Bacteria, yeast, plants, metazoans RibD Bacteria, archea, yeast, plants GuanineD Bacteria, ... recently a crystal structure for a functionally characterized AID/APOBEC was not available and many of the structural features of this protein family have...

Ngày tải lên: 14/08/2014, 08:21

... enzymatically active MAPs, and structural MAPs. We focus here on the MAP2/Tau family of structural MAPs, which along with the MAP 1A/ 1B family form one of the ‘clas- sical’, well-characterized families ... [45-48]. Functions of MAP4 and non-neuronal functions of MAP2 and Tau The widely expressed non-neuronal member of the MAP2/Tau family, MAP4, shares many features...

Ngày tải lên: 14/08/2014, 14:21

... rodents and humans (Table 1), it is likely that they are the result of an internal duplication. According to the phylogenetic tree, AP-2 ␦ genes appear to have separated from the rest of the family ... capa- bility or DNA-binding affinity of the other AP-2 family members. The crystal structure of the AP-2 proteins has not yet been solved. Localization and function...

Ngày tải lên: 14/08/2014, 16:20

... were alike for all of the major TF classes or if the apparent difference between the TFs and the non-TFs was primarily driven by a particular TF class. All of the large TF classes with at least about ... perturbation (for example, in a logical analysis [2] or in an experimental approach [3]). These works clearly show the added value of a systems approach. Note that s...

Ngày tải lên: 09/08/2014, 20:21

... combination with additional statistically and clini- cally relevant covariates. Country alone was not used as a covariate to predict either treatment administration or mortality primarily because of ... perhaps as a rescue therapy in the younger patient, after other therapies had failed. It may also imply that there is a developing practice to use DrotAA on those patients perceive...

Ngày tải lên: 13/08/2014, 16:21

... to all of the data in the study and takes responsibility for the integrity of the data and the accuracy of the data anal- ysis. QZ and STP participated in study design; acquisition, analysis, and ... interpretation of data; manuscript preparation; and statistical analysis. YL participated in study design; acqui- sition, analysis, and interpretation of data; and statistic...

Ngày tải lên: 09/08/2014, 10:21

... permutation-based P-value < 0.05 after 1000 permutations. Association with genotyped SNPs and age-at-onset (AAO) of bipolar disorder was analyzed by performing a quanti- tative trait analysis ... School of Medicine, Indianapolis, IN, USA, 5 Department of Psychiatry, UC San Diego, La Jolla, CA, USA and 6 Pediatric Psychopharmacology Unit, Massachusetts General Hospital; Psychia...

Ngày tải lên: 11/08/2014, 17:20

... is especially true during the teenage and early adult years, relates mainly to cyclothymia and probably represents attempts at self-medication for the mood liability. During the withdrawal period many ... confrontation and to a significant extent they lack self-examination and insight; because of this lack of insight, mania nearly always, sooner or later, acquires a delusional c...

Ngày tải lên: 08/08/2014, 23:21

... plates and incubated for 72 hours at 37°C. DNase activity in the supernatants was measured by DNA-MG assay, as set out below. DNA-methyl green assay DNase I activity in urine and supernatant samples ... surface antigens. Detailed analysis of these autoantibodies by many researchers has revealed several key findings. First, nuclear antigens are prom- inent with anti-double-stranded DNA (...

Ngày tải lên: 09/08/2014, 07:20