Báo cáo y học: "Antagonizing Methuselah to extend life span" pot

... peptide binding to the Mth ectodomain. The Mth ectodomain structure [13] was visualized with PyMOL (PyMOL Molecular Graphics System). The tryptophan (W) residue previously thought to be positioned ... artificial modulator of GPCR activity could extend life span. Although Mth has no homologs in humans, is it likely that a modulator of a signaling pathway could be used as a drug to de...

Ngày tải lên: 14/08/2014, 08:20

... [(2R)-2-[((3R0-3-(1,3-benzodiol-5-yl)-3-{[(6-methoxy- 2-napthyl)sulfonyl]amino}propanoyl)amino]-3-(4-{[2R,6S)-2,6- dimethylpiperidyl]methyl}phenyl}-N-isoproyl-Nmethylpropana mide hydrochloride], a new nonpeptide ... models of cutaneous inflammatory pain were developed initially as pharmacodynamic assays of anti- inflammatory drug activity, particularly for NSAIDs. Typically, primary endpoints...

Ngày tải lên: 09/08/2014, 10:20

... they divided DR Congo into two strata along the 2001 line of military con- trol: an east stratum of territory formerly held by rebel groups and a west stratum of territory formerly held by government ... 5 [36,37], the reliability of a mortality estimate can vary widely. If one were to rely only on the first estimate from that study, as many have, one would incorrectly infer that 500,000 ch...

Ngày tải lên: 25/10/2012, 10:31

... a or by structuring the major category itself (say into binary N and V features plus a bar-level feature as in ~-based theo- ries). F.rcing the primacy and atomicity of major category defeats ... structured category systems. Sec, m,l. and perhaps more critically, because only cer- tain ,ff the information in a rule is used to guide the parse, say major category information, only suc...

Ngày tải lên: 31/03/2014, 17:20

... tuyến thành phố có trang thiết bị tốt, hiện đại hơn tuyến quận/huyện. Thực tế n y cũng cho th y người có thẻ BHYT nghèo thiệt thòi hơn các đối tượng khác. KÕt luËn Nghiên cứu cho th y ... khi được cấp thẻ BHYT. Tuy nhiên, một số y u tố: mất thời gian chờ đợi vì xa cơ sở đăng ký khám chữa bệnh ban đầu (bắt buộc ở tuyến trung tâm y tế quận/huyện), thủ tục BHYT còn rườm rµ, p...

Ngày tải lên: 07/08/2014, 00:23

... phần của *ĐHYD TPHCM; **ĐHYK Huế; ***ĐHY Hải Phòng, ****ĐHY Hà Nội; *****YK Bắc Thái; ******ĐHYD Cần Thơ; ******* Khoa Y ĐH T y Nguyên; ********Bộ Y tế Phản biện khoa học: GS. TS. Lê ... niên Việt Nam; Y u tố ảnh hưởng. affected factors to height, weight and BMI on vietnamese youths Le Dinh Van; Truong Dinh Kiet; Nguyen Huu Chinh; Nguyen Thi Binh; Nguyen Thanh Tr...

Ngày tải lên: 07/08/2014, 03:20

... although mainly giving rise to symptoms at night, is usu- ally not dyspneic. The presence of nocturnal dys- pnea, with or without cough, especially in the set- ting of cardiac dysfunction or coronary artery disease, ... shown to improve symptoms of asthma and airway hyper- responsiveness. 22 Identifying and managing upper respiratory inflammation is therefore important, especially in the...

Ngày tải lên: 08/08/2014, 21:20

... proliferate. 21 Unfortunately, chymotrypsin digestion does not retain this T-cell epitope. This may be one of the reasons why lymphocyte responses to chymotrypsin-digested BLG peptides became lower than those to BLG. Finally, ... responses to dietary protein antigens. Immunol Today 1987;8:93–8. 8 Allergy, Asthma, and Clinical Immunology, Volume 3, Number 1, 2007 ORIGINAL ARTICLE Lymphoc...

Ngày tải lên: 08/08/2014, 21:20

... obstruction may lead to mouth breathing, allowi ng an increased quantity of allergens to penetrate into the lower airways, inducing inflammation, and potentially triggering asthma symptoms. The other ... pre-determined by skin titration. B efore spraying, subjects were asked to inhale through their mouth to total lung capacity and to hold their breath, in order to avoid lower airw...

Ngày tải lên: 08/08/2014, 21:20

... addition to the auditory effect. It would be interesting to exclude other sensory inputs while evaluating the potential enhancement of eating pleasure by listening to chewing sounds. In this study, ... citation purposes) Annals of General Psychiatry Open Access Primary research Does listening to the sound of yourself chewing increase your enjoyment of food? Kirsty E Amos, Shahram Ana...

Ngày tải lên: 08/08/2014, 21:20