Báo cáo y học: "Evolutionary history and functional implications of protein domains and their combinations in eukaryotes" pptx

... animal-spe- cific combinations consist of 558 domains, and the 610 deu- terostome-specific combinations consist of 478 domains. Among them, 72 domains in animal-specific combinations and 50 domains in deuterostome-specific ... eukaryotes, in terms of the preference for generation of domain combinations. Results Assignment of domains and their combinat...

Ngày tải lên: 14/08/2014, 07:21

... G, Melino G, Lee SC, Steinert PM: Protein unfolding by peptidylarginine deiminase. Substrate specificity and structural relationships of the natural sub- strates trichohyalin and filaggrin. J ... by inflammatory cells via their Fcγ receptors. This will activate these cells and cause the release of extra proinflammatory cytokines. D Various polymorphisms in proinflammatory cyto...

Ngày tải lên: 09/08/2014, 01:23

... with an N-terminal histidine tag was constructed by inserting the Correspondence to D. Kang, Department of Clinical Chemistry and Laboratory Medicine, Kyushu University Graduate School of Medical ... because of induction of unregulated replication [18]. In addition, guanine-rich RNA can participate in very stable three- stranded structures by establishing both Watson–Crick and...

Ngày tải lên: 23/03/2014, 21:20

... retrace a genuine species phylogeny. Fur- thermore, by focusing on relatively small groups of proteins, it is possible to identify and remove proteins affected by LGT by performing single phylogenetic ... peculiarity of M. kandleri is its histone protein, formed by the fusion of two monomers into a single polypeptide containing two tandemly repeated histone folds [50]. Interestingly,...

Ngày tải lên: 09/08/2014, 20:21

... of CTCF binding sites containing a canonical CTCF binding motif is plotted as a function of the number of top-ranked binding sites for both the individual and combined datasets. The results of ... used enrichment of the ER bi nding motif to evaluate the quality of the inferred enriched regions. By mapping the occurrence of the ER binding motif within a 500-bp window surroundin...

Ngày tải lên: 09/08/2014, 22:23

... periods in a sleep diary and collected urine samples during each day's main sleep period. The samples were subsequently assayed for the metabolite of melatonin in urine, 6- sulphatoxymelatonin ... melatonin production in forced desynchrony protocols, the current results indicate that low production of melatonin may play a role in the poor consolidation of daytime sleep i...

Ngày tải lên: 10/08/2014, 09:20

... maneuver) and maintain the strain with their respiratory muscles for 3 seconds. Physiotherapy of protocol On the day preceding surgery, patients received orien- tation and training regarding the physiotherapeutic procedures ... goal of optimizing pul- monary function. Physiotherapy, including incentive spirometry, should be continued in the postoperative period. Limitations of t...

Ngày tải lên: 10/08/2014, 09:21

... substrates p70 ribosomal S6 kinase 1 and eukaryotic initiation factor 4E binding protein 1 result- ing in increased translation of proteins promoting cell proliferation and cellular metabolism [1,2]. ... mitomycin-C), radiation therapy within 4 weeks, surgery within 3 weeks before starting study drug, or treatment with strong CYP3A inhibitors or inducers within 5 days before startin...

Ngày tải lên: 10/08/2014, 21:23

... difficulty in swallowing liquids and had a history of regurgitation of food after meals. There was no history of cough or diffi- culty in breathing during meals, thus ruling out the possi- bility of ... of lymph nodes. All other findings were within normal limits. Fine needle aspiration cytology from the lump of the left breast suggested an infiltrating ductal carcinoma....

Ngày tải lên: 11/08/2014, 12:20

... NTPase/primase binding domain (Table 1, Figure 2) [22,26]. Thymidylate kinase The poxvirus thymidylate kinase (TMPK) encodes a 48 kDa serine threonine protein kinase (A48R) [27] that reg- ulates deoxyribonucleotide ... within virulence genes such as the A-type inclusion protein, serine protease inhibitor-like protein SPI-3, Schlafen ATPase and thymidylate kinase, among others. Aberran...

Ngày tải lên: 12/08/2014, 04:20