Báo cáo y học: "A new integrative weaning index of discontinuation from mechanical ventilation" pot

... our study, the new integrative IWI presented the area under the ROC curve of 0.96 and f/Vt of 0.85. Our hypothesis to justify the difference between the accuracy of CROP index and that of IWI ... Meta-analysis under the spotlight: focused on meta-analysis of ventilator weaning. Crit Care Med 2008, 36:1-7. 11. Yang KL, Tobin MJ: A prospective study of indexes predicting the...

Ngày tải lên: 13/08/2014, 19:20

... versions of synucleins, together w ith the A30P and A53T mutants of a-synuclein that cause f amilial c ases of Parkinson's disease. Unfortunately the quality of s ome of these syn uclein ... spectra of all these proteins are very similar to those of disordered poly( L - glutamic acid) at high pH and poly( L -lysine) at low pH [18,19]. Accordingly, the ROA spectra of disor...

Ngày tải lên: 21/02/2014, 15:20

... SOCS-3. Peptide K d (l M ) pY343 > 30 pY401 9.5 ± 0.12 pY429pY431 1.1 ± 0.03 F429pY431 4.6 ± 0.02 pY429F431 4.9 ± 0.02 Y4 2 9Y4 31 ND pY443 ND pY461pY464 ND Y4 61pY464 ND pY46 1Y4 64 ND pY479 ND Ó FEBS 2002 ... specifically interact with the tyrosine motifs pY401 and pY429pY431. pY429pY431 was more potently recruiting SOCS-3 than pY401, reflecting the high affinity binding determined by SPR...

Ngày tải lên: 24/03/2014, 00:21

... cell lysates bind to a GST fusion of the cytoplasmic domain of siglec-10. Ten micrograms of GST alone, GST– cyto-wt and GST– cyto -Y6 67F were tyrosine phosphorylated (-P) with a mixture of Lck, ... as asthma may offer new and effective approaches to immunomodulatory therapy. In an attempt to identify such new targets on inflammatory cells at sites of inflammation, we searched the...

Ngày tải lên: 24/03/2014, 04:21

... Scrutton 1 Departments of 1 Biochemistry and 2 Chemistry, University of Leicester, UK Recent years have witnessed high levels of activity in iden- tifying enzyme systems that catalyse H-transfer by quantum tunneling. ... increasing the catalytic efficiency of enzymes in the biotechnology industry (by enhancing the coupling of dynamics to the reaction coordinate), and (b) producing mo...

Ngày tải lên: 31/03/2014, 23:20

... the analysis of the S2 effect, for example, the association may be overestimated by the presence of S3D carriers in the control group (noncarrier of S2). The effect of S2 may similarly be underestimated ... effect of S2 and S3P in the analysis of S3D, the asso- ciation with negativity of anti-CCP2 remained significant. These results support the hypothesis of an association bet...

Ngày tải lên: 09/08/2014, 10:20

... phase of the light-dark cycle was reversed every 48 hours (as if this group of rats instantly travelled back and forth from Asia to the Americas every other day). Animals were housed individually ... both nurses over the course of the seven-day measurement period, which indicate prolonged times of rest and, usually, darkness. Although many analyses of the activity and of the tra...

Ngày tải lên: 10/08/2014, 09:20

... Angiography of the right coronary artery with the presence of a large saccular aneurysm involving the distal part of the artery to the crux cordis. (C) Partial opacification of the aneurysmal sac through ... 4). Conclusions Coronary artery aneurysms may be complicated by thrombosis and rupture. The optimal treatment options of coronary aneurysms are still largely debated. They inclu...

Ngày tải lên: 11/08/2014, 03:21

... patient’s largest coronary vessel by 1.5 to 2 times. Coronary artery aneurysms are typically diagnosed by coronary angiography. The prognosis of coronary artery aneurysm is not well known and ... 68-year-old Italian-Caucasian man presented to our hospital with angina. Coronary angiography revealed a large coronary aneurysm of the right coronary artery, which was successfully treated by th...

Ngày tải lên: 11/08/2014, 07:20

... cells were matured over two days, harvested and analyzed for cell yield and mature DC phenotype by flow cytometry, and then functionally analyzed for their ability to activate allogeneic T-cell ... to adhere monocytes on to plastic in static flasks from PBMC followed by culture with GM-CSF and IL-4 and maturation using any one of a number of cocktails of pro-inflammatory cytokines (IL...

Ngày tải lên: 11/08/2014, 10:23