Handbook of Pediatric Cardiovascular Drugs - part 6 docx

Handbook of Pediatric Cardiovascular Drugs - part 6 docx

Handbook of Pediatric Cardiovascular Drugs - part 6 docx

... to long-term maintenance doses of 0.05 to 0.15 mg/kg/day. Some centers continue low-dose Table 8-1 . Potential combinations of immunosuppressive drugs used in pediatric thoracic transplan- tation a Number ... mL/min, admin- ister 25% of normal dose or use alternative agent Pharmacokinetics The onset of action of bretylium is 6 to 20 minutes, with a peak effect at 6 to 9...

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Handbook of Pediatric Cardiovascular Drugs - part 1 docx

Handbook of Pediatric Cardiovascular Drugs - part 1 docx

... incidence of serious drug-drug interac- tions in pediatric patients receiving chronic antiepilepsy drugs. 12 Implications of CYP-450 Drug-Drug Interactions of Cardiovascular Drugs The CYP-450 system ... effects. 1 Protein-Binding Effects Drugs in plasma bind to proteins, including albumin, -1 -acid- glycoprotein ( -1 -AG), and lipoproteins. Albumin is the major serum prot...

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Handbook of Pediatric Cardiovascular Drugs - part 2 ppt

Handbook of Pediatric Cardiovascular Drugs - part 2 ppt

... Vasoconstricted - Warm - Vasoplegic - Fever Normal CVP - Dobutamine - Calcium chloride - Phenylephrine - Vasopressin - Dopamine - Dobutamine Low CVP Filling Myocardial dysfunction Norepinephrine Figure 3-3 . ... albumin - Rule out hemorrhage - Arrhythmia? - Pacemaker - Atropine - Isoprenaline Optimal Normal for the age HR - Fluid r...

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Handbook of Pediatric Cardiovascular Drugs - part 4 ppsx

Handbook of Pediatric Cardiovascular Drugs - part 4 ppsx

... onset of action of approximately 1 hour and a duration of action of 12 to 24 hours. Oral absorption of the drug is dependent on the prepa- ration used, and protein binding is 95%. The half-life ... Strategies for Prevention. Ann Int Med 1991; 114 :66 7 67 7. 3. Taketomo CK, Hodding JH, Kraus DM. Lexi-Comp’s Pediatric Dosage Handbook, 13th Edition, 20 06. Nitrates: Nitroprussi...

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Handbook of Pediatric Cardiovascular Drugs - part 5 pdf

Handbook of Pediatric Cardiovascular Drugs - part 5 pdf

... 86( 14): 566 –574. 10. Borges, H., J. Hocks, and C. Kjellstrand (1982). “Mannitol intoxication in patients with renal failure.” Arch Intern Med 142(1): 63 66 . 6. b-Blockers 145 worsen the degree of ... concentrations four- to seven-fold higher than healthy patients after a single dose Pharmacokinetics Carvedilol has an onset of action of α-blockade within 30 minutes and of β-bl...

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Handbook of Pediatric Cardiovascular Drugs - part 7 pot

Handbook of Pediatric Cardiovascular Drugs - part 7 pot

... Sear JW, Valvini EM. Kinetics of methaemoglobin and serum nitrogen oxide production during inhalation of nitric oxide in volunteers. Br J Anaesth 19 96; 76: 652 65 6. 60 . Rimar S, Gillis CN. Selective ... Anesthesiology 1994; 81: 61 6 62 2. 30. Bogaert WA, Herregods LL, Mortierr EP. Cardiopulmonary bypass and pharmacoki- netics of drugs. Clin Pharmacokinet 1989; 17: 10– 26. 31....

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Handbook of Pediatric Cardiovascular Drugs - part 8 pdf

Handbook of Pediatric Cardiovascular Drugs - part 8 pdf

... incidence of intracranial hemorrhage and other hemorrhagic compli- cations of ECMO. J Pediatr Surg 1993; 28: 5 36 541. 6. Horwitz JR, Cofer BR, Warner BH, Cheu HW, Lally KP. A multicenter trial of 6- amino- caproic ... effects of insulin. Table 1 1-2 Time since last dose Dose of protamine <30 minutes 100% of above dosing recommendations 30 60 minutes Administer 50–75% of...

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Handbook of Pediatric Cardiovascular Drugs - part 9 pps

Handbook of Pediatric Cardiovascular Drugs - part 9 pps

... Propofol: an overview of its pharmacology and a review of its clinical efficacy in intensive care sedation. Drugs 1995; 50 :63 6 65 7. 2. Bryson HM, Fulton BR, Faulds D. Propofol: an update of ... depres- sion because of its nonopioid mechanism of analgesia. Dexmedetomidine has a 160 0-fold greater affinity for the α2-receptor compared with α1-receptors. 33 One of the highe...

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Handbook of Pediatric Cardiovascular Drugs - part 10 pps

Handbook of Pediatric Cardiovascular Drugs - part 10 pps

... 155– 160 lidocaine, 1 56 157 mexiletine, 157–158 phenytoin, 158– 160 class IC, 160 – 163 flecainide, 160 – 161 propafenone, 161 – 163 class II (β-blockers), 163 –170 atenolol, 166 – 167 esmolol, 163 – 164 metoprolol, ... 252–255 argatroban, 255–257 aspirin, 257– 260 clopidogrel, 260 – 262 dipyridamole, 262 – 264 enoxaparin, 264 – 267 heparin, 267 – 269 lepirudin, 269 –272 liothyro...

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Handbook of Lubrication Episode 1 Part 6 docx

Handbook of Lubrication Episode 1 Part 6 docx

... rupturing, the short-bearing results given here for the half-sleevebearing of Figure 4 apply equally well to radial motion of the full-sleeve bearing of Figure 6. 128CRC Handbook of Lubrication FIGURE ... constants.) Thus, ∋ 1 26 CRC Handbook of Lubrication 12 1-1 37 4/11/ 06 12:28 PM Page 1 26 Copyright © 1983 CRC Press LLC thermal reduction factor, φ T , which can be mu...

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