Báo cáo y học: "Anti-inflammatory effects of Radix Gentianae Macrophyllae (Qinjiao), Rhizoma Coptidis (Huanglian) and Citri Unshiu Pericarpium (Wenzhou migan) in animal models" doc

... primary ingre- dient in Radix Gentianae Macrophyllae is gentiopicroside which was shown to have anti-inflammatory effects in a murine model of hepatic injury [9]. Berberine, which has strong anti-inflammatory ... pel- lets. Delayed type hypersensitivity Female BALB/c mice were sensitized by epicutaneously applying 25 μl of a mixture of acetone and olive oil (4:1) containin...

Ngày tải lên: 13/08/2014, 15:21

... MY, Kim YJ, Han CW, Choi YC: Dual knockdown of p65 and p50 subunits of NF-kappaB by siRNA inhibits the induction of inflammatory cytokines and significantly enhance apoptosis in human primary ... [12] and secretion of cytokines and chemokines [13]. Specific cytokines and chemokines produced by macro- phages during Mtb infection play important roles in reg- ulating the ho...

Ngày tải lên: 13/08/2014, 14:20

... The anti-inflammation effect of Paeoniflorin on cerebral infarction induced by ischemia-reperfusion injury in Sprague-Dawley rats. Am J Chin Med 2010, 38(1):51-64. 31. Yang GY, Mao Y, Zhou LF, ... inhibit prostaglandin F-2a, oxytocin, acetylcholine chloride and potassium depolarization-induced uterine contraction, * Correspondence: clhsieh@mail.cmuh.org.tw 1 Department of Chinese Med...

Ngày tải lên: 13/08/2014, 14:20

... results in induction of TNF-α and IFN-γ by immunocytes, and suggest that these cytokines could play a crucial role in the induction of arthritis in GPI-induced mice. Anti-cytokine mAbs and co-stimulator ... production during this phase of GPI-induced arthritis. Figure 4 Concentration of inflammatory cytokines in serum of mice with GPI-induced arthritisConcentration of...

Ngày tải lên: 09/08/2014, 10:23

... pharmacodynamic effects in the lungs. Terbutaline and formoterol have been shown to inhibit plasma extravasation in inflamed airways of guinea- pigs and rats [3] and formoterol reduced histamine- induced ... Detrimental effects of albuterol on airway responsiveness requires airway inflammation and is independent of b-receptor affinity in murine models of asthma. Resp...

Ngày tải lên: 12/08/2014, 13:22

... chromatin and thereby the DNA is exposed to highly reactive ROS which induce single strand breaks in the DNA. In cells, generally, these toxic effects are eliminated by repair enzymes. Poly-(ADP-ribose)-polymerases ... protein KillerRed-Lamin B being part of such membranes. Mapping studies of the initial DNA strand breaks in apoptotic Jurkat cells indicated an accumu- lati...

Ngày tải lên: 25/10/2012, 11:15

... of dimyristoylglycerophosphocholine (Myr 2 Gro-PCho), dimy- ristoylglycerophosphoethanolamine (Myr 2 Gro-PEtn) and dimyristoylglycerophosphoglycerol (Myr 2 Gro-PGro) by DSC, in order to determine their effects on ... suggesting that these peptides readily incorporate into Myr 2 Gro-PGro bilayers in the liquid-crystalline state and remain incorporated in the gel state. Permeabili...

Ngày tải lên: 21/02/2014, 01:21

... Zhang,L.,Ahvazi,B.,Szitner,R.,Vrielink,A.&Meighen,E. (1999) Change of nucleotide specificity and enhancement of cat- alytic efficiency in single point mutants of Vibrio harveyi aldehyde dehydrogenase. Biochemistry 38, 11440–11447. 33. ... nicotinamide and one for the adenosine moiety [31]. 2¢-Adenyl nucleotides, of the type found in NADPH, and the 5¢-nucleotides used in t...

Ngày tải lên: 22/02/2014, 04:20

... synthetase, inhibition of CoA-IT results in an increase in free AA and a corresponding build-up of AA in triacylglycerols that can be prevented by co-incubation of cells with CoA-synthetase inhibitors ... 1-acyl-linked phospholipids (mainly PtdCho and PtdIns) was being remodeled into the ether- linked subclasses (1-alkyl-2-AA-GPC and 1-alk-1-enyl-2- AA-GPE). Examination of...

Ngày tải lên: 22/02/2014, 07:20

... mild hyperplasia of the synovial lining, but without any evidence of inflammatory cells being observed (Fig. 5A,B). There were some inflammatory cells in the contralateral synovial lining, but ... inflammation in arthritic joints, TGF-β1 expression induced fibrogenesis and muscle edema. In addition, TGF-β1 expression in the ade- novirally infected synovial lining also resulted...

Ngày tải lên: 09/08/2014, 01:21