Báo cáo y học: "Differential effects of Radix Paeoniae Rubra (Chishao) on cytokine and" pptx

... Faculty of Medicine, The University of Hong Kong, Pokfulam, Hong Kong SAR, PR China. 2 Cytokine Biology Group, Department of Paediatrics and Adolescent Medicine, The University of Hong Kong, Pokfulam, ... Pokfulam, Hong Kong SAR, PR China. 3 Department of Pharmacology and Pharmacy, The University of Hong Kong, Pokfulam, Hong Kong SAR, PR China. 4 Purapharm International Hong Kon...

Ngày tải lên: 13/08/2014, 14:20

... constitutes the bulk of the fatty acid at the sn-2 position of 1-alkyl-2-acyl-GPC under resting conditions [70]. Upon cell activation, most of this AA is replaced by other fatty acids. Finally, ... activation is accompanied by an increase in PAF biosynthesis via acetylation of 1-alkyl-2-lyso-GPC by acetyl transferase (Fig. 8, f) activity, competition for 1-alkyl-2-lyso-GPC intermediat...

Ngày tải lên: 22/02/2014, 07:20

... i.v.) exerts anti-inflammatory action by reducing the generation of 4-hydroxy-2-nonenal (4-HNE), 8-hydroxy-2’-deoxygua- nosine (8-OHdG) and apoptosis in the reperfusion period after cerebral ischemia, ... ischemia/reperfusion injury. Zhongguo Meitan Gongye Yixue Zazhi 2009, 12(11):1773-1774, In Chinese. 45. Peng HY, Du JR, Zhang GY, Kuang X, Liu YX, Qian ZM, Wang CY: Neuroprotective effect...

Ngày tải lên: 13/08/2014, 14:20

... con- clusions on the importance of the neuronal target were drawninastudyontheroleofIL-6onthegeneration of pathophysiological heat hyperexcitability [30]. Con- cerning the success of systemic treatment, ... primary mechanical hyperalgesia in the acute phase of AIA. By contrast, repeated systemic application of sgp130 after onset of AIA only slightly attenuated pain at a late sta...

Ngày tải lên: 12/08/2014, 14:22

... Central Page 1 of 3 (page number not for citation purposes) Respiratory Research Open Access Correction Differential effects of cigarette smoke on oxidative stress and proinflammatory cytokine release ... error and any inconvenience or confusion it may have caused. Published: 18 January 2008 Respiratory Research 2008, 9:6 doi:10.1186/1465-9921-9-6 Received: 3 January 2008 Accepted:...

Ngày tải lên: 12/08/2014, 15:21

... ethidium bromide. Glutathione concentration was measured by enzymatic recycling assay and 4-hydroxy-2- nonenal levels by using lipid peroxidation assay kit. The levels of proinflammatory cytokines (e.g. IL-8 ... N, Seweryniak K, Maggirwar SB, Kilty I, Rahman I: Cigarette smoke induces proinflammatory cytokine release by activation of NF-κB and post-transla- tional modifications of his...

Ngày tải lên: 12/08/2014, 16:20

... T cell responses, possibly as part of a negative feedback loop. This is supported by the observation by Kim and colleagues that administration of rTNFα suppressed IFNγ production by antigen-stimulated ... Furthermore, studies from the laboratory of Cope and colleagues have shown that prolonged exposure of T cells to TNFα in the context of RA leads to the induction of hyporesponsiv...

Ngày tải lên: 09/08/2014, 10:23

... were treated with the Poly [ADP-ribose] polymerase (PARP) inhibitor ABT-888 (final concentration 5µM) Recombinatory chemistry of the fusion plasmid The construction of the pKillerRed-Lamin ... impact on aging as well as diseases which are associated with mitochon- drial DNA mutations are discussed [11-15]. The connection between ROS activity and cellu- lar toxicity is beyond cont...

Ngày tải lên: 25/10/2012, 11:15

... including those that affect myc gene expression, Myc protein stability, and Myc bio- logical activity. Normal regulation of Myc activity occurs by mechanisms that influence the Myc protein per se [7], ... isoforms at the levels of Myc antagonism in the REF assay, subcellular localization, and transcrip- tional activity. Some of these analyses have assigned differential functions to the t...

Ngày tải lên: 18/02/2014, 16:20

... analogs on the thermotropic phase behavior of LMVs composed of dimyristoylglycerophosphocholine (Myr 2 Gro-PCho), dimy- ristoylglycerophosphoethanolamine (Myr 2 Gro-PEtn) and dimyristoylglycerophosphoglycerol ... Ronald N. McElhaney 1,2 1 Department of Biochemistry, University of Alberta, Edmonton, Alberta, Canada; 2 Protein Engineering Network of Centers of Excellence, Universi...

Ngày tải lên: 21/02/2014, 01:21