Báo cáo y học: "Animal models of copper-associated liver disease" doc

... study of the role of metallothionein in the inherited copper toxicosis of dogs Biochem J 1986, 236:409-415 94. Kelly WR The liver and biliary system Pathology of Domestic Ani- mals (Edited by: ... retention [6]. Primary biliary cirrhosis Primary biliary cirrhosis is a chronic progressive, often fa- tal liver disease, characterized by the eventual develop- ment of cirrhosis and...

Ngày tải lên: 13/08/2014, 13:20

... expres- sion of human alpha(1)-antichymotrypsin enhances alzheimer-like pathology in amyloid protein precursor transgenic mice. Am J Pathol 157, 2003–2010. 129 Wyss-Coray T, Lin C, Yan F, Yu GQ, Rohde ... pharmacology of the drug should preferably be carried out before efficacy is tested in APP transgenic mice. Unfortu- nately, many drug candidates or dietary supplements are simply directl...

Ngày tải lên: 16/02/2014, 09:20

... of Physics, Pennsylvania State University, University Park, PA 16802, USA Abstract Background: One of the goals of computational immunology is to facilitate the study of infectious diseases. Dynamic ... specific use of simple and complex models in the study of the progression of infectious diseases. Conclusions: Models of sub-systems or simplified immune response can be us...

Ngày tải lên: 13/08/2014, 16:20

... hibitor of reCBG [the hydrolysis of 4NP-b- D - glucopyranoside (10 m M ) was reduced by 98% in the presence of 4NP-b- D -mannopyranoside (10 m M )]. Hydrolysis of xenobiotic glycosides by reCBG The ... puri®cation of CBG and allowed characterization in s ome detail, especially with respect to its glycone/aglycone speci®city a nd ability to catalyse the hydrolysis of dietary xenobi...

Ngày tải lên: 08/03/2014, 16:20

... Goronzy JJ: Tissue cytokine patterns in patients with polymyalgia rheumatica and giant cell arteritis. Ann Intern Med 1994, 121:484-491. 25. Wagner AD, Goronzy JJ, Weyand CM: Functional profile of ... symp- tomatic PAD that could impact the patients' quality of life – as opposed to asymptomatic disease. The present study adds to the growing body of literature per- taining to the ri...

Ngày tải lên: 09/08/2014, 14:20

... between orthologs of YPO0254 and YPO0274 [9]. Species within the Yersinia genus had either the Y. enterocolitica type of ysa TTSS locus or the Y. pestis/SPI-2 type (with the exception of Y. aldo- vae, ... overall similarity to Y. enterocolitica: Y. kristensenii, Y. frederiksenii, Y. mollaretii, Y. intermedia, Y. bercovieri, Y. aldovae, Y. rohdei, Y. ruckeri, Y. pseudotuber...

Ngày tải lên: 09/08/2014, 20:21

... be ( a ) ubr4 12 12 12 12 pA+ pA- pA+ pA- HeLa H9 nup155 16 16 16 16 pA+ pA- pA+ pA- H9 HeLa Bimorphic ( b ) znf207 15 15 15 15 pA+ pA- pA+ pA- HeLa H9 Genes HeLa UBR4 WDFY3 NUP155 SFRS18 PDK4 ZKSCAN EIF3A ZRANB1 SF3B2 PHKB ZNF217 H9 Y Y Y Y - Y Y Y Y Y Y Y Y Y Y Y Y Y Y Y Y Y Chr 1 4 5 6 7 7 10 10 11 16 20 Bimorphic pA+ Y Y Y - Y Y - - - Y Y - - - Y - - Y Y...

Ngày tải lên: 09/08/2014, 22:23

... the light-dark cycle and lowest at the light- dark transition. Daily rhythmicity of nociception in ratsFigure 1 Daily rhythmicity of nociception in rats The figure shows the daily variation in ... probably an arti- fact of the experimental procedure, as only two time points during the day were reported. A study on mice sug- gested the occurrence of two daily peaks in sensitivity, one...

Ngày tải lên: 10/08/2014, 09:20

... and evolution of IBD. Because of this prime role of TNF-α in IBD, anti-TNF-α antibody therapy has been very successfully used in IBD to reduce both colonic injury and expression of ECAMs in IBD ... currently a key therapy in IBD [36]. While it has been previously shown that delivery of IL-10 to the endothelium in vitro is protective against TNF-α [36], in vivo administration of IL...

Ngày tải lên: 11/08/2014, 08:21

... Veroux 2 * Addresses: 1 Department of Surgery, Transplantation and Advanced Technologies, Anaesthesia and Intensive Care Unit, University Hospital of Catania, Via Santa Sofia, 95123 Catania, Italy and 2 Department of Surgery, ... deeply seated, large soft tissue masses in the subcutis or salivary glands, without significant change in the underlying skin [2]. Less frequently, the eyelids...

Ngày tải lên: 11/08/2014, 17:21