... Norway5Department of Medical Biochemistry, Institute of Medical Biology, Faculty of Medicine, University of Tromsø, Norway6Department of Medical Physiology, Institute of Medical Biology, Faculty of Medicine, ... protein C (APC), which is catalyzed by the action of thrombin/thrombomodulin complex when protein C is boundto its endothelial receptor (endothelial cell protein C receptor).Acting together ... ovineendotoxin-induced lung injury, a frequently used model of acute lung injury. Recombinant human activated protein C (rhAPC),with its anticoagulant, anti-inflammatory, fibrinolytic andantiapoptotic effects,...