Báo cáo y học: " Beyond the first 25 years: The International AIDS Society and its role in the global response to AIDS" pps

... AccessCommentary Beyond the first 25 years: The International AIDS Society and its role in the global response to AIDS Pedro Cahn and Craig McClure*Address: International AIDS Society, 33, Chemin de ... dialogue, and to strengthen the focus on youth – began to be implemented in the planning for the XVI International AIDS Conference (AIDS 2006) in Toronto and will be implemented morefully in planning ... opportunities for its membership is important forany professional society, and the IAS is looking at ways to strategically expand its role in this area in order to strengthen the capacity of the HIV workforce.The...

Báo cáo y học: " Increased expression of matrix metalloproteinase-10, nerve growth factor and substance P in the painful degenerate intervertebral disc" pot

... moredetailed investigation into these pathways, including analysisof enzyme activities, is required to better understand the underlying pathogenesis.Competing interests The authors declare that they have ... sensory neurons[28,29] and intrinsic airway neurons [30], which may lead to increased nociception in painful IVD degeneration. The aim of the current study was to examine the gene and pro-tein ... V and IX[18]. In addition to this proteolytic activity, MMP-10 has beenshown to play a role in the activation of a number of othermembers of the MMP family in a range of cell types, includingarticular...

Báo cáo y học: "ntravenous transplantation of allogeneic bone marrow mesenchymal stem cells and its directional migration to the necrotic femoral head"

... intravenously injected into nude mice and the distribution and mi-gration of MSCs were dynamically monitored to evaluate the feasibility and safety of intravenous im-plantation of allogeneic MSCs in ... distributed in the right hip joint. Subse-quently, MSCs migrated into almost all organs, and were uniformly distributed in the brain, lungs, heart, kidney, intestine, hip joints and other organs ... intravenously injected autologous and allogeneic MSC into baboons, and no toxic reactions were observed during 1-year follow-up [41]. Another intravenously injected allogeneic ma-caque MSCs into macaques...

Báo cáo y học: "A web tool for finding gene candidates associated with experimentally induced arthritis in the rat" docx

... selecting and ranking keywords, and searching OMIM text for selected keywords.Finding a QTL of interest The first step in finding candidate genes for a specific QTL is to choose a QTL of interest. ... severity in rats [29]. On looking at the OMIM text for NCF1, it is clear thatmost of the points come from the part of the text describingthese particular findings. To evaluate the ability of the tool ... found in the OMIM reference lists. Finally, the NCF1 gene was studied in detail.Cia4 In total, 12 genes were ranked by the CGC tool. IFNG wasrated as the top candidate by the CGC application and...

Báo cáo y học: "Contribution for new genetic markers of rheumatoid arthritis activity and severity: sequencing of the tumor necrosis factor-alpha gene promoter" docx

... neuropathyconfirmed by electromyography, or the diagnosis of Sjögrensyndrome based on the clinical symptoms of dry eyes and drymouth (confirmed by a positive Schirmer's test and/ or kerato-conjunctivitis ... personally observed most of the patients and coordinated and trained others to perform the same observa-tions, coordinated and trained observers for the use of the SvdH method, participated in the ... modifying the binding of transcription factors [24]. On the other hand, the -857CC genotype appears to be associ-ated with a worse response to etanercept in patients with RA [25] , and studies in healthy...

Báo cáo y học: "Effect of small interference RNA (siRNA) for ADAMTS5 on intervertebral disc degeneration in the rabbit anular needle-puncture model" pptx

... to the AF area. In a previous study using the rab-bit anular puncture model, the injection of osteogenic protein-1 into the NP induced an increased proteoglycan content ofboth the AF and the ... analysis, and interpretation of data. KMparticipated in the design of the study and finalized the manu-script. YK and TK participated in the design of the study and performed the statistical analysis. ... Hoyland JA, Freemont AJ: Interleukin-1 receptorantagonist delivered directly and by gene therapy inhibitsmatrix degradation in the intact degenerate human interverte-bral disc: an in situ zymographic...

Báo cáo y học: "Predicting outcome of rethoracotomy for suspected pericardial tamponade following cardio-thoracic surgery in the intensive care unit" ppt

... previous history of chronic renal insufficiency and use of heparin, acetylsalicylic acid and clopidrogel. The type of primary surgery was retrieved. The chart of the rethoracotomy was evaluated ... haemodynamic parameters including, forworst values within 24 h prior to rethoracotomy, worstvalue within and at 24 h after rethoracotomy, and forthose directly prior to and after rethoracotomy ... preopera-tively, than patients without such fall in CV SOFA.Predictors of response prior to and during rethoracotomyPatients having had heparin between primary surgery and rethoracotomy tended to have...

Báo cáo y học: " Evidence for preferential copackaging of Moloney murine leukemia virus genomic RNAs transcribed in the same chromosomal site" ppt

... retroviral vectors contain-ing different selectable markers and one of the vectorshaving a deletion of the PBS region. These vectors wereintroduced into the packaging cell line using two differentmethods, ... strand transfersduring minus and plus DNA synthesis. Since the retroviralvirion contains two molecules of the viral RNA, the first DNA transfer might be either intramolecular, transferring to ... cell line would be tandemly integrated into the host genome. To study the integration of plasmid DNA, the PCR analysis was performed with the primers hybrid-izing to the 3' end of neo gene...

Báo cáo y học: " Activation instead of blocking mesolimbic dopaminergic reward circuitry is a preferred modality in the long term treatment of reward deficiency syndrome (RDS): a commentary" potx

... consequences beyond cardio-vas-cular disease and diabetes. Current findings link bothobesity and ADHD to the dopamine system and implicatedopamine genes in body weight, eating, and ADHD,among others. ... nature of the disorder. These researchers have used positron emissiontomography to investigate in humans the role ofdopamine (DA) and the brain circuits it regulates in theseprocesses. They have ... prima-rily a behavioral problem of overeating and under-exercis-ing has only contributed to continued increases in the rates of obesity despite increases in dieting, exercise and the understanding...

Báo cáo y học: "Cell-specific microarray profiling experiments reveal a comprehensive picture of gene expression in the C. elegans nervous system" ppsx

... T10B10.5SNB-1UNC-43RAB-3UNC-13UNC-10F45E4.3SNN-1RIC-4Neurotransmitterbiosynthetic enzymesUNC -25 CHA-1TDC-1Proton pumpCamKIISynapsinSynaptobrevinSynaptotagminSNAP -25 RIMZK637.1SNG-1SynaptogyrinSVOPOCT-1F45E10.2EAT-4CAT-1UNC-17UNC-46UNC-47Endocytosis ... on the synaptic vesicle cycle and genes withkey roles in this mechanism are elevated in both datasets:these include unc-18, snt-1 (syntaxin), snn-1 (synapsin), ric-4(SNAP -25) , sng-1 (synaptogyrin), ... expression in the brain in this case was confirmed by direct visualization of the in situphotographs available in the Brain Atlas.C. elegans interactomeGenes enriched in both the larval and embryonic...

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