Báo cáo y học: "Selenium supplementation in critically ill patients: can too much of a good thing be a bad thing" potx

... much of a good thing be a bad thing? Daren K Heyland Clinical Evaluation Research Unit, Angada 4 Kingston General Hospital, Kingston, ON K7L 2V7, Canada Corresponding author: Daren K Heyland, dkh2@post.queensu.ca Published: ... apoptosis of cells causing a maladaptive inflammatory reaction by means of a pro-oxidative mechanism may be beneficial. However, no evidenc...

Ngày tải lên: 13/08/2014, 08:20

... the anemia of the critically Ill: hepcidin as a diagnostic tool? Anemia is not only very frequent among critically ill patients, it is also associated with increased transfusion rates and worse ... reaction. Large amounts of iron, exceeding the transferrin iron-binding capacity, may thus be toxic by inducing the release of free iron and causing oxidative stress.  is p...

Ngày tải lên: 14/08/2014, 07:21

... frequently seen in critically ill patients, may result in the intrusion of delta frequency waves into the wake state, leading to an overestimation of sleep time. Thus, for accurate interpretation ... Bernard GR, Gordon S, Francis J, May L, Truman B, Speroff T, Gautam S, Margolin R, Hart RP, Dittus R: Delirium in mechanically ventilated patients: validity and relia- bility of...

Ngày tải lên: 13/08/2014, 08:20

... immunocompetent patients are largely lacking [17,18]. Employment of potent antiviral therapy in all critically ill patients may be impractical, logistically infea- sible, and potentially harmful given a large ... and antiviral therapy targeted towards patients with viral replication are routinely employed at many transplant centers. APACHE: Acute Physiology and Chronic Health Eval...

Ngày tải lên: 13/08/2014, 16:20

... cacy and safety of LMW heparin for thromboprophylaxis in orthopaedic and abdominal surgery was achieved with dosages of heparin resulting in peak plasma anti-factor Xa activities ranging between ... that critically ill patients have signi cantly lower plasma anti-factor-Xa activity levels compared to control patients after administration of subcutaneous heparin. Robinson...

Ngày tải lên: 13/08/2014, 20:21

Ngày tải lên: 13/08/2014, 11:22

... Agan BK, Tasker SA, Spooner KM, Armstrong AW, Fraser S, Wallace MR: Comparisons of causes of death and mortality rates among HIV-infected persons: analysis of the pre-, early, and late HAART ... treatment advances have con- verted AIDS from a disease that was almost universally fatal within a few months to a chronic disease that can be controlled for many years [1]. A maj...

Ngày tải lên: 13/08/2014, 20:22

Ngày tải lên: 12/08/2014, 19:22

... demonstrated that a restrictive transfusion strategy was at least as effective as a liberal one. In addition, applying a liberal transfusion strategy resulted in a significantly higher multiple organ ... concentrates in critically ill patients remains controversial and has generated much research and debate in the medical literature. A recent, large, noninferiority ran...

Ngày tải lên: 13/08/2014, 03:21

... human RA as well as in other animal models of RA, the activation of JNK may be caused by another disease-relevant signalling pathway such as IL-1, which is a potential inducer of JNK phosphorylation ... previous data, the results of Goertz and colleagues also emphasise the role of ERK1/2 as a key integrator of activation signals in synovial fibroblasts. In contrast, th...

Ngày tải lên: 09/08/2014, 07:20