Harper’s Illustrated Biochemistry - Part 3 pdf

... (6-phospho- fructo-2-kinase/fructose-2,6-bisphosphatase). (PFK-1, phosphofructokinase-1 [6-phosphofructo-1-kinase]; F-1,6-Pase, fructose-1,6-bisphosphatase. Arrows with wavy shafts indicate allosteric effects.) fructose-1,6-bisphosphatase. ... 6-phosphate H 2 O P i GLUCONEOGENESIS GLYCOLYSIS Glycogen Glucose Pyruvate Citrate F-1,6-Pase PROTEIN PHOSPHATASE-2 Inactive F-2,6-Pase Active PFK-2 A...

Ngày tải lên: 13/08/2014, 07:20

... hemolymph. 1 O- - D -Glucopyranosyl-(1 → 1 )- - D -glucopyranoside. HO H HOCH 2 H OH H H OH O H O- - D-Glucopyranosyl-(1 → 4 )- -D-glucopyranose O- - D-Glucopyranosyl-(1 → 2 )- -D-fructofuranoside 3 5 6 4 H HOCH 2 H OH H H OH O OH H 5 6 4 O Maltose ** 11 232 HO H HOCH 2 H OH H H OH O H 3 5 6 4 O Sucrose 1 2 * HOCH 2 1 O OH ... + ⋅ + Substrate A-H A-OH P450-A-H Fe 3...

Ngày tải lên: 13/08/2014, 07:20

... is linked to the heterocyclic base via a ␤-N-glycosidic bond, almost al- ways to N-1 of a pyrimidine or to N-9 of a purine (Fig- ure 33 3) . ch 33. qxd 3/ 16/04 10:59 AM Page 286 PORPHYRINS & ... clinical in- terest because they are excreted in increased amounts in ch32.qxd 2/ 13/ 20 03 3:57 PM Page 2 73 318 / CHAPTER 36 A B 5C BR3 BR3 5C Figure 36 –4. Illustration of the tight co...

Ngày tải lên: 13/08/2014, 07:20

... properties. ch37.qxd 3/ 16/04 11:02 AM Page 35 5 38 6 / CHAPTER 39 HMGI-Y ATF-2 cJun NF-κB IRF(IRF3/7) HMG PRDIV PRDII NRDI HMG HMG HMG PRDI-III IRF3 HMGI HMGI HMGI HMGI ATF-2 cJun IRF7 NF-κB Figure 39 –9. ... repres- sion, as discussed below. ch39.qxd 3/ 16/04 11:04 AM Page 37 6 40S 1A 80S Formation of the 80S initiation complex 3 AUG Met Cap (A) n 1A 3 2 Met 1A 3 2 AUG Met Cap...

Ngày tải lên: 13/08/2014, 07:20

... ENZYME ANGIOTENSINASES Asp-Arg-Val-Tyr- I le-His-Pro-Phe-His-Leu-Leu (~400 more amino acids) Asp-Arg-Val-Tyr- I le-His-Pro-Phe-His-Leu Asp-Arg-Val-Tyr- I le-His-Pro-Phe Arg-Val-Tyr- I le-His-Pro-Phe Figure ... α-Hydroxylase24-Hydroxylase HO HO 27 25 24 26 HO CH 2 CH 2 OH OH 7-Dehydrocholesterol 1,25(OH) 2 -D 3 24,25(OH) 2 -D 3 1,24,25(OH) 3 -D 3 25-Hydroxycholecalciferol (25[OH]-D 3...

Ngày tải lên: 13/08/2014, 07:20

... “arrowheads.” (Courtesy of JA Spudich.) ATP-Myosin ADP-P i -Myosin Actin H 2 O Actin ATP ADP + P i Actin-Myosin Actin-Myosin ADP-P i Actin-Myosin ATP 1 2 3 4 5 Figure 49–6. The hydrolysis of ATP ... proteins” (or re- actants) and include C-reactive protein (CRP, so-named because it reacts with the C polysaccharide of pneumo- cocci), α 1 -antitrypsin, haptoglobin, α 1 -acid glycopro- tein, a...

Ngày tải lên: 13/08/2014, 07:20

... hydrolases, including α-neuraminidase, β-galactosidase, β-hexosaminidase, - and β-mannosidases, α-N-acetylgalactosaminidase, α-fucosidase, endo- β-N-acetyl- glucosaminidase, and aspartylglucosaminidase. ... α1 ,3 GlcUA GalNAc 2-Sulfate β1,4 β1 ,3 GlcUA Gal β1,4 β1 ,3 Gal β1 ,3 Xyl β1,4 Ser β 4-Sulfate Chondroitin sulfates: GlcUA GalNAc β1,4 β1 ,3 GlcUA Gal β1,4 β1 ,3 Gal β1 ,3 Xyl...

Ngày tải lên: 22/03/2014, 21:20

... well-ordered crystals. To establish appropriate Forkhead transcription factor DNA-bindingNLS Pr-Pr 6-Phosphofructo-2-kinase/Fructose-2,6-bisphosphatase Reg RegCatalysis Pr-Pr RegCatalysis Pr-Pr Pr-Pr Catalysis Catalysis Phenylalanine ... hydrolyze pep- tide bonds and generate peptides with as few as two or three amino acids. Each peptide was reacted with 1- uoro-2,4-dini- IEF SDS PAGE 01=...

Ngày tải lên: 22/03/2014, 21:20

... Cleaved CNBr Met-X Trypsin Lys-X and Arg-X Chymotrypsin Hydrophobic amino acid-X Endoproteinase Lys-C Lys-X Endoproteinase Arg-C Arg-X Endoproteinase Asp-N X-Asp V8 protease Glu-X, particularly ... 80 34 / CHAPTER 5 N 280 34 5 30 55 50 33 0 35 0 90 230 245 260 258 30 0 31 0 32 0 220 110 170 125 120 205 145 150 185 C 37 7 70 15 80 Figure 5–6. Examples of tertiary structure of pro-...

Ngày tải lên: 08/04/2014, 12:42

... 8.01E–4 32 1.1065E–2 8.7740E 3 0.7 930 228.5 8.890E+2 1 .35 5E–2 30 3.0 14.86 1.10E 3 34 8.0709E 3 6.5470E 3 0.8112 233 .7 6. 634 E+2 9.887E 3 306.5 15.14 1.53E 3 36 5.9245E 3 4.9198E 3 0. 830 4 239 .3 4.985E+2 ... 1.8 438 E 3 1.6727E 3 0.9072 261.4 1.695E+2 2.259E 3 324.1 16.57 7 .34 E 3 46 1 .39 92E 3 1.2961E 3 0.92 63 266.9 1 .31 3E+2 1.714E 3 327.5 16.85 9.83E 3 48...

Ngày tải lên: 08/08/2014, 11:21