DNA Methylation: Basic Mechanisms - Part 4 ppsx

... Vanyus h in BF (1981) 5-Met h y l cytosine in pyrim- i d ine sequences o f p l ant an d anima l DNA: speci fi city o f DNA met h y l ation. Bio- c h emistry (Mosc) 46 : 145 8– 147 4 Kirnos MD, Ba k eeva ... R (20 04) Ro l eo f transposa bl ee l ements in h eteroc h romatin an d epigenetic contro l. N ature 43 0 :47 1 47 6 1 2 6 W. D oe rfl er 4. 2Th e E1A Pr o m ote r o fA d 12 DNA...

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... sequences, or heterochromatic re g ions [visual - ized b y intense 4  - 6  - diamidino-2-phen y lindole (DAPI) stainin g ; Koch and Stra t l ing 20 04] . Intriguing l y, t h eaut h ors f oun d an ... mar k ers f or l ive c e ll ana l yses. Ce ll Cyc l e 4: 453 45 5 Felsenfeld G, Groudine M (2003) Controllin g the double helix. Nature 42 1 :44 8 45 3 Fisher AG, Merkenschla g...

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... aci d o f t h etu b erc l e b aci ll us . Su b sequent ly , 5-mC h a d a b ioc h emica lf uture as 5- hyd rox y met hyl -C ( 5- h m-C) in the DNA of the T-even bacterio pha g es. The biolo g ical function o f t h is C mo d i fi cation ... meth y lation mech- anisms. In our l a b oratory, t h ese consi d erations h ave prompte d investigations on the sta bilit y of food-in g ested DNA...

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... Genet 33 Supp l : 245 –2 54 J e ff eryL,Na k ie l ny S (20 04) Components o f t h e DNA met h y l ation system o f c h romati n control are RNA-binding proteins. J Biol Chem 279 :49 479 49 48 7 J ones PA, ... ompose d o f small g ene-rich re g ions intermixed with 5- to 200-kb blocks of repetitiv e DNA. The repetitive DNA blocks are usuall y meth y lated at 5  - CG -3  a n...

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... non-5  -CG -3  C-residues were never meth y lated. Around exon 1 of the S NRPN g ene, more t h an 96% o f t h e23 5  - CG - 3  - d inuc l eoti d es were met h y l ate d on t h emater - na l c h romosome, ... Pol y merase I-Transcr i bed Human R i bosomal Gene s Th e5  - CG - 3  -rich promoter re g ion of the DNA- dependent RNA pol y merase I (rDNA) g enes wa...

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... Heteroc h romatin f ormatio n SUMO-1 N-termina l Sma ll u b iquitin-re l ate d protein Ubc9 N-terminal SUMO-1 E2 con j u g atin g enz y me PIAS1 N-terminal SUMO-1 E3 li g ase PIA S x α N-termina l SUMO-1 E3 l igase Dnmt3L ... distribution of the hamster intracisternal A- p article (IAP) retro - trans p osons. Chromosoma 1 04: 341 – 344 Muiznie k sI,Doer fl er W (1994a) T h eimpacto f5  -...

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... (20 04 b )T h e Dnmt1 DNA- (cytosine-C5)-met h y l - trans f erase met h y l at es DNA processive l ywit hh ig h pre f erence f or h emimet h y - l ate d target sites. J Bio l C h em 279 :48 350 48 35 9 H sie h CL ... German y a. j eltsch@iu-bremen.de 1In t r oduct i o n 2 04 2Cata l ytic Mec h anism o f DNA- (Cytosine-C5)-MTases . 20 6 2.1 Reaction Mec h anism o f DNA- (Cy...

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... trophoblast . Placenta 24: 20 9 –218 E l-Maarri O (20 04) SIRPH anal y sis: SNuPE with IP-RP-HPLCfor quantitativemeasure- ments of DNA meth y lation at specific CpG sites. Methods Mol Biol 287:195–20 5 El -Maarri ... o f ce ll cyc l e proteins E2F-1, C dk -2 , Cy- c l in E, p27( k ip1), an d Ki-67 in norma l p l acenta an d gestationa l trop h o bl astic d i sease. M od P at h o l 14 : 1...

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... an d tumorigenesis in MBD 4- d e fi cient mice. Science 297 :40 3 40 5 Mor g an HD, Dean W,Coker HA, ReikW, Petersen-Mahrt SK (20 04) Activation-induce d c y tidine deaminase deaminates 5-meth y lc y tosine in DNA and ... 16:1 241 –1 247 D iNoiaJ,Neuber g er MS (2002) Alterin g the pathwa y of immuno g lobulin h y permuta- tion b y inhibitin g uracil -DNA g l y cos y lase. Nature 41 9...

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... islands of non-meth y lated, CpG-rich DNA. C ell 40 : 9 1– 99 Bir d AP, Taggart MH, Nic h o ll s RD, Higgs DR (1987) Non-met h y l ate d CpG-ric h is- l an d satt h e h uman a l p h a-g l o b u l in l ocus: ... 213 p ro l i f erating-ce ll nuc l ear antigen 27 , 190 – (PCNA)-interactin g do m a in 1 84 p romoter 68, 70, 71, 74, 84 88, 90, 94 , 95 , 97 , 102 , 10 3 p rom y eloc y tic le...

Ngày tải lên: 13/08/2014, 07:20