BIOPHARMACEUTICALS BIOCHEMISTRY AND BIOTECHNOLOGY - PART 2 potx

... Microbiol. 49, 27 7–304. Normark, B. & Normark, S. (20 02) . Evolution and spread of antibiotic resistance. J. Intern. Med. 25 2 (2) , 91–106. Tudzynski, P. et al. (20 01). Biotechnology and genetics ... 57(5–6), 593–605. Walsh, C. (20 02) . Combinatorial biosynthesis of antibiotics, challenges and opportunities. Chembiochem. 3 (2 3), 125 –134. PHARMACEUTICALS, BIOLOGICS AND...

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... therapeutic 8 BIOPHARMACEUTICALS Interleukin-1 (IL-1) 23 2 The biological activities of IL-1 23 3 IL-1 biotechnology 23 4 Interleukin-3: biochemistry and biotechnology 23 5 Interleukin-4 23 6 Interleukin-6 23 8 Interleukin-11 ... C 8 H 11 N 5 O 3 22 5 .2 Anti-viral agent Zidovudine C 10 H 13 N 5 O 4 26 7 .2 Anti-viral agent Dexamethasone C 22 H 29 FO 5 3 92. 5 Anti-infl...

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... Follicle-stimulating hormone (FSH) CHO Insulin E. coli Interferon-b CHO Erythropoietin CHO Interferon-a E. coli Glucocerebrosidase CHO Interferon-g E. coli Factor VIIa BHK Interleukin -2 (IL -2 ) E. ... Sciences, Ireland The media constituents, several of which are heat-labile, are generally dissolved in WFI and filter-sterilized into the pre-sterile animal cell reactor. Reactor design (and...

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... increased androgen and oestradiol synthes is by these cells. IGF-1 also promotes increased expression of FSH and LH receptors in ovarian tissue. 28 4 BIOPHARMACEUTICALS IGF biochemistry IGF-1 and -2 were ... paracrine- and autocrine-based activity. In the human female, IGF-1 is expressed by follicular theca cells, while IGF -2 is synthesized by granulosa cells (Chapter 8). The...

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... 1–10. Plotkin, S. (20 02) . Vaccines in the twenty-first century. Hybridoma Hybridom. 21 (2) , 135–145. Poland, G. et al. (20 02) . Science, medicine and the future — new vaccine development. Br. Med. J. 324 (7349), ... from up to 23 serotypes of Streptococcus pneumoniae Edelman, R. (20 02) . The development and use of vaccine adjuvants. Mol. Biotechnol. 21 (2) , 129 –148. Esparza, J. e...

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... Protein Molecular mass (kDa) IFN-a 20 27 TNF-a 52* EGF 6 IFN-b 20 GM-CSF 22 NGF 26 IFN-g 20 25 G-CSF 21 Insulin 5.7 IL -2 15 20 EPO 36 hGH 22 IL-1 17.5 TPO 60 FSH 34 IL- 12 30–35 IGF-1 7.6 LH 28 .5 *Biologically ... receptor superfamily Receptors for IL -2 7, -9 , -1 2, G-CSF, GM-CSF, EPO, LIF, CNTF, GH The Interferon receptor superfamily Cytokine receptor type II family R...

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... cytokines (including IL -2 , -4 , -5 , -6 , -7 , -1 1, -1 5 and CSFs) also play important co- stimulatory roles in the maturation of the range of blood cells. Its growth and differentiation-inducing effects ... factors (CSFs) and platelet-derived growth factor (PDGF) Cell type Interleukins produced Macrophages IL-1, IL-6, IL-10, IL- 12 Eosinophils IL-3, IL-5 Vascular en...

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... diabetes mellitus. Clin. Sci. 92( 4), 321 –330. Drucker, D. (20 02) . Biological actions and therapeutic potential of the glucagon-like peptides. Gastroenterology 122 (2) , 531–544. Goa, L. et al. (1997). ... the presence of 2, 3-DPG and at normal tissue oxygen partial pressures, over 20 % of the bound oxygen is released from haemoglobin; in the absence of 2, 3-DPG, this value falls to...

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... focuses upon alleviating CF symptoms, 3 92 BIOPHARMACEUTICALS neutralized by another plasma protein, a 2 -antiplasmin (a 2 -antiplasmin, a 70 kDa, single-chain glycoprotein, binds plasmin very ... for safety. Haemophilia 8 (2) , 63–75. Federici, A. & Mannucci, P. (20 02) . Advances in the genetics and treatment of von Willebrand disease. Curr. Opin. Pediat. 14(1) 23 –33. Goodey,...

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... 5 02 3 haemopoietic growth factors 25 7–8 IL-1 23 2–5 IL-1a 23 2–3 IL-1Ra 23 4 IL-1b 23 2–3 IL -2 224 , 22 5– 32 IL-3 23 5–6, 25 7–8 IL-4 22 4, 23 6–8 IL-5 24 1–3 IL-6 23 8–40 IL-10 22 4 IL-11 24 0–1 IL- 12 244–6 IL-13 ... 20 3–7 biotechnology 20 7–10 IFN-a 122 , 196, 197–8, 21 0–13, 520 –6 IFN-b 122 , 196, 197, 198, 21 3–14 IFN-g 196, 197, 198, 21 4–16, 27 8 IFN-g 1B...

Ngày tải lên: 13/08/2014, 07:20