Báo cáo y học: "Human endogenous retrovirus-FRD envelope protein (syncytin 2) expression in normal and trisomy 21-affected placenta" doc

... purposes) Retrovirology Open Access Short report Human endogenous retrovirus-FRD envelope protein (syncytin 2) expression in normal and trisomy 21-affected placenta André Malassiné 1,2,5 , Jean-Louis ... proteins, the widely studied syncytin 1, encoded by HERV-W and the recently characterized syncytin 2 encoded by HERV-FRD. Here we studied syncytin 2 in normal...

Ngày tải lên: 13/08/2014, 06:20

... glycoprotein (Junin Virus and Lymphocytic Choriomeningitis Virus), intracel- lular trafficking, fusion or virus infectivity in general [77- 80]. In HFV, SP affects viral particle assembly and ... Western blotting using anti-SP. Cellular β-actin was analyzed as a loading control. Larger-sized protein bands, including the protein band slightly larger than SP in the left-hand West...

Ngày tải lên: 13/08/2014, 05:21

... (PcG) family of proteins [1-7]. The human EED protein, also called WAIT-1 (for WD protein associated with integrin cytoplasmic tails-1; [8]), can interact with the cytoplasmic tail of integrin β7 subunit, ... β7 subunit, a domain which is involved in major integrin functions such as receptor affinity and signaling [9,10]. EED was also found to interact with three HIV-1 proteins, the Ga...

Ngày tải lên: 13/08/2014, 05:22

... Genome Biology 2005, 6:404 Correction Correction: A DNA microarray survey of gene expression in normal human tissues Radha Shyamsundar* † , Young H Kim*, John P Higgins*, Kelli Montgomery*, Michelle ... microarray hybridization (prostate RNA versus normal genomic DNA) used to derive the plot in Figure 4a became corrupted during data processing. The corrected plot (Figure 4a) display...

Ngày tải lên: 14/08/2014, 14:22

... whereas ZPB is the primary sperm binding protein in pigs and rabbits [6,8,9]. All of the zona pellucida glycoproteins in the mouse are synthesized coordinately by the oocytes [10], whereas the granulosa ... by inhibiting protein transport from RER to the Golgi apparatus by BFA, and that ZPC and the 12-kDa fragment generated by the proteolytic processing of proZPC are accumulated...

Ngày tải lên: 24/03/2014, 03:21

... the production of cytokines and chemokines including TNF-α, IL-1, IL-6 and IL-8 [15-17]. IL-17A also up-regulates MMP expression by chondrocytes and synoviocytes resulting in cartilage damage ... show- ing IL-17A induced MMP expression in human OA chondro- cytes [41] and in RA synoviocytes [18]. In animal cells IL-17A has been previously shown to act synergistically with T...

Ngày tải lên: 09/08/2014, 14:22

... fur- ther to determine its sensitivity and specificity. Finally, when faced with the dilemma of urgently starting chemo- therapy in a patient whose condition is deteriorating and whose clinical presentation ... studies showed that inflammatory cytokines, such as interferon gamma, induce HHV-8 replication in the PMBCs of HIV-infected patients and in primary effusion lymphoma cell l...

Ngày tải lên: 11/08/2014, 17:21

... assay [45]. Since this assay is very stringent as a result of diluting the cultures 1:3 weekly, slowly growing or non-dividing cells are eliminated very quickly and the percentage of sur- viving ... disease associated with infection. In addition to the structural and enzymatic proteins, HTLV encodes regulatory (Tax and Rex) and accessory proteins. Tax and Rex positively regulate v...

Ngày tải lên: 13/08/2014, 05:20

... Treatment 1 23 20 60 40 80 40 0 CTLL-2 Tax2B-3 1 2 3 20 60 40 80 4 0 0 CTLL-2 Tax2B-6 CsA(-) CsA0.5ǴM CsA1.0ǴM 123 20 60 40 80 40 0 CTLL-2 Tax2B-7 123 20 60 40 80 4 0 0 CTLL-2 Tax2B-8 12340 20 60 40 80 0 CTLL-2 Tax1-2 12340 80 20 60 40 0 CTLL-2 Tax1-6 12 3 100 200 4 0 0 CTLL-2+IL-2 Expression of Tax protein in transformed cells Figure 2 Expression of Tax protein in transformed cel...

Ngày tải lên: 13/08/2014, 09:20

... Matsushime H, Yoshida M: HTLV-1 Tax protein interacts with cyclin-dependent kinase inhibitor p16INK4A and counteracts its inhibitory activity towards CDK4. Embo J 1996, 15:1607-1614. 30. Jin DY, Spencer ... mainly induces the increase of CD4-positive T-lymphocytes in vivo by enhanced proliferation and suppressed apoptosis. In HTLV-I-infected individuals, no virions are detected in...

Ngày tải lên: 13/08/2014, 09:21