... 18 19 20 21 22 23 24 25 26 27 28 29 30 31 Malassine A, Handschuh K, Tsatsaris V, Gerbaud P, Cheynet V, Oriol G, Mallet F, Evain-Brion D: Expression of HERV-W Env glycoprotein (syncytin) in the ... by abnormal human chorionic gonadotropin signaling in trisomy 21 pregnancies Endocrinology 20 07, 148(11):5403-5413 Cheynet V, Oriol G, Mallet F: Identification of the hASCT2-binding domain of ... and in the mesenchymal core of the villi (Fig 2A–B) In second trimester placenta (Fig 2C–D), syncytin immunostaining was present: 1 /in the cytoplasm of cytotrophoblastic cells; 2/ in their thin...
Ngày tải lên: 13/08/2014, 06:20
... 01 82 Thyroid 0 029 Testes 1853 Testes 1068 Testes 0553 Brain, temporal cortex 22 72 Brain, occipital cortex 22 71 Brain, frontal cortex 22 71 Brain, frontal cortex 22 72 Brain, occipital cortex 22 73 ... NKX3-1 AA 229 499 PAK1IP1 TRIP8 AA 425 6 92 AMD1 AI0785 52 AMD1 AA 229 573 RDH11 RDH11 STEAP2 KIAA1411 AA7 724 97 FLJ13409 PRIM2A MSH2 ACLY TTRAP ABCC4 NKX3-1 AA 229 499 PAK1IP1 TRIP8 AA 425 6 92 AMD1 AI0785 52 AMD1 ... duodenum 21 74 Colon, sigmoid 0361 Colon 20 75 Kidney 026 5 Kidney 1651 Kidney 1594 Kidney 022 6 Kidney 0088 Liver 0560 Liver 127 4 Liver 126 7 Liver 00 32 Liver 0586 Pancreas 26 50 Pancreas 04 32 Thymus 0512...
Ngày tải lên: 14/08/2014, 14:22
Báo cáo y học: "Regulation of catabolic gene expression in normal and degenerate human intervertebral disc cells: implications for the pathogenesis of intervertebral disc degeneration" ppt
... gene expression in malignant carcinoma via TNF-R1 [25 ], and TNF-R1 but not TNF-R2 has been shown to be important in inflammatory responses involving IL-1β and MMP-3 and -9 in murine brain injury ... Hoyland JA: A preliminary in vitro study into the use of IL-1Ra gene therapy for the inhibition of 23 24 25 intervertebral disc degeneration Int J Exp Pathol 20 06, 87:17 -28 Le Maitre CL, Freemont ... in gene expression in alginate and monolayer culture Spine 20 01, 26 :1747-1751 discussion 17 52 Nerlich AG, Boos N, Wiest I, Aebi M: Immunolocalization of major interstitial collagen types in human...
Ngày tải lên: 09/08/2014, 14:20
Báo cáo y học: "Arctigenin from Arctium lappa inhibits interleukin-2 and interferon gene expression in primary human T lymphocytes" docx
... that they have no competing interests 19 20 21 22 Received: 14 October 20 10 Accepted: 25 March 20 11 Published: 25 March 20 11 23 References Kuo YC, Yang NS, Chou CJ, Lin LC, Tsai WJ: Regulation ... article as: Tsai et al.: Arctigenin from Arctium lappa inhibits interleukin -2 and interferon gene expression in primary human T lymphocytes Chinese Medicine 20 11 6: 12 Submit your next manuscript ... Wnt/beta-catenin signaling Food Chem Toxicol 20 10, 48 :22 47 -22 52 Arai K, Lee F, Miyajima A: Cytokines: Coordinators of immune and inflammatory response Annu Rev Biochem 1990, 59:783-836 Serfling E, Berberich-Siebelt...
Ngày tải lên: 13/08/2014, 14:20
Báo cáo khoa học: Diverging regulation of pyruvate dehydrogenase kinase isoform gene expression in cultured human muscle cells pot
... (LY2940 02) [25 ,26 ], were used to examine the role of PtdIns3K in regulating PDK transcript abundance in response to insulin (Fig 2) Incubation with either LY2940 02 (50 lm) or wortmannin (100 ... pathway in regulating PDK mRNA expression was investigated by incubating myoblasts for h in the presence of insulin (1 lm) and U0 126 (100 lm) U0 126 failed to reverse the effects of insulin on PDK2 ... kinase-3 (GSK3) and the mammalian target of rapamycin (mTOR) GSK3 is inactivated in response to insulin via a PtdIns3K ⁄ protein kinase B (PKB)dependent pathway [27 ,28 ] Involvement of GSK3 in...
Ngày tải lên: 07/03/2014, 17:20
Báo cáo khoa học: Ascorbic acid-pretreated quartz enhances cyclo-oxygenase-2 expression in RAW 264.7 murine macrophages pdf
... the principle of protein-dye binding Anal Biochem 72, 24 8 25 4 34 Singh IS, He JR, Calderwood S & Hasday JD (20 02) A high affinity HSF-1 binding site in the 5¢-untranslated region of the murine tumor ... Pharmacol 158, 21 1 22 0 21 Hinz B & Brune K (20 02) Cyclooxygenase -2 10 years later J Pharmacol Exp Ther 300, 367–375 22 Brown JR & DuBois RN (20 04) Cyclooxygenase as a target in lung cancer Clin Cancer ... further incubated for h at 37 °C COX -2 expression and PGE2 production were quantified as described below Measurement of murine COX -2 expression and PGE2 production Expression of murine COX -2 in RAW 26 4.7...
Ngày tải lên: 23/03/2014, 10:20
Báo cáo sinh học: "MiRNA-205 modulates cellular invasion and migration via regulating zinc finger E-box binding homeobox 2 expression in esophageal squamous cell carcinoma cells" pptx
... 16 17 18 19 20 21 22 23 24 25 26 27 28 Case No Intraepithelial ESCC (n=7) Well (n=7) Moderate (n=5) Poor (n=9) Invasive ESCC (n =21 ) B Ratio of miR -20 5 expression Ratio of miR -20 5 expression levels ... cell leukemia-1 expression Matsushima et al Journal of Translational Medicine 20 11, 9:30 http://www.translational-medicine.com/content/9/1/30 20 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 ... pre-miR200b Scramble pre-miR205 miR -20 5 precursor Wound healing 0.8 0.6 0.4 0 .2 0h 12h 24 h 48h 72h B ZEB1 ZEB2 E-cadherin N-cadherin Phospho-Akt -actin Control anti-miR -20 5 inhibitor Control miR -20 5...
Ngày tải lên: 18/06/2014, 19:20
Báo cáo toán học: " Effects of internal low-dose irradiation from 131 I on gene expression in normal tissues in Balb/c mice" ppt
... (2) 9% (2) 8% (1) 8% (1) 4% (1) 38% ( 12) 12% (3) 3% (1) 9% (2) 18% (2) 22 % (2) Spleen 26 0 kBq 8% (1) 7% (1) 8% (2) 13 kBq 12% (3) 19% (5) 28 % (9) 20 % (6) 3% (1) 13% (3) 15% (2) 22 % (7) 9% (2) 4% ... (3) 27 % (8) 57% (21 ) 46% (6) 30% (7) 30% (7) 17% (5) 11% (4) 15% (2) 10% (3) 5% (2) 17% (5) 16% (6) 10% (3) 8% (3) 18% (2) 27 % (3) 42% (5) 5% (1) 8% (1) 22 % (2) 9% (2) 25 % (3) 27 % (3) 17% (2) ... Cyp4a12a (2. 9) Abcc3 ( -2. 7) Cyp7b1 (3.0) Akr1c 12 ( -2. 8) Krt13 (50) Cyp2d9 (5.0) Cyp2e1 (3 .2) Ly6f (-3.6) Krtdap (59) Dao1 (11) Inmt (3.8) Ddx6 (-3.9) Lce3c (27 ) LOC100048556 (6.3) Inmt (4.0) Cyp2d9...
Ngày tải lên: 20/06/2014, 21:20
Báo cáo khoa học: " Cap-independent protein translation is initially responsible for 4-(N-methylnitrosamino)-1-(3-pyridyl)-butanone (NNK)-induced apoptosis in normal human bronchial pithelial cells" pot
... Con 12: Control 12 hrs; Con24: Control 24 hrs; R: Rapamycin, N4: NNK, hrs; RN4: Rapamycin + NNK, hrs; N 12: NNK, 12 hrs; RN 12: Rapamycin + NNK, 12 hrs; N24: NNK, 24 hrs; RN24: Rapamycin + NNK, 24 ... C: Control; R: Rapamycin; N4: NNK, hrs; RN4: Rapamycin + NNK, hrs; N 12: NNK, 12 hrs; RN 12: Rapamycin + NNK, 12 hrs; N24: NNK, 24 hrs; RN24: Rapamycin + NNK, 24 hrs; Inh: inhibitor (B) Time course ... RN4: Rapamycin + NNK, hrs; N 12: NNK, 12 hrs; RN 12: Rapamycin + NNK, 12 hrs; N24: NNK, 24 hrs; RN24: Rapamycin + NNK, 24 hrs; Inh: inhibitor Time-dependent changes of Bax, Bid, Bcl -2, and Cytochrome...
Ngày tải lên: 07/08/2014, 18:20
Báo cáo y học: "Dynamic compression counteracts IL-1β induced inducible nitric oxide synthase and cyclo-oxygenase-2 expression in chondrocyte/agarose constructs" pdf
... articular chondrocytes Matrix Biol 20 02, 21 :25 1 -26 2 23 Malemud CJ: Protein kinases in chondrocyte signaling and osteoarthritis Clin Orthop Relat Res 20 04, 427 (suppl):145-151 24 Badger AM, Cook MN, Lark ... transcriptional induction of the human inducible nitric oxide synthase gene requires both AP-1 and NF-κB binding sites J Biol Chem 1998, 27 3 :22 201 -22 208 28 Fermor B, Weinberg JB, Pisetsky DS, Misukonis ... the integrins in mediating the mechanotransduction process, including downregulation of NO and PGE2 release, both in the presence and absence of IL-1β, utilizing iNOS and COX -2 specific inhibitors...
Ngày tải lên: 09/08/2014, 10:23
Báo cáo y học: "Bone Morphogenetic Protein (BMP)-4 and BMP-7 regulate differentially Transforming Growth Factor (TGF)-β1 in normal human lung fibroblasts (NHLF)" pdf
... terminal differentiation-the role of Smad proteins Exp Cell Res 20 03, 28 2 (2) :90-100 12 Phipps S, Benyahia F, Ou TT, Barkans J, Robinson DS, Kay AB: Acute allergen-induced airway remodeling in ... interleukin-1beta-stimulated matrix metalloproteinase-13 expression in human chondrocytes J Biol Chem 20 03, 27 8 (28 ) :25 386 -25 394 47 Li H, Simon H, Bocan TM, Peterson JT: MMP/TIMP expression in spontaneously hypertensive ... fibroblast-related expression of MMP-13 but also the induced expression of this protein following stimulation by TGF-β1 MMP-13, an interstitial collagenase, is the principal enzyme involved in the initiation...
Ngày tải lên: 12/08/2014, 11:22
Báo cáo y học: " Smoking-mediated up-regulation of GAD67 expression in the human airway epithelium" doc
... 20 6 525 _ at 20 821 7_at GABRR1 GABRR2 gamma-aminobutyric acid (GABA) receptor, rho gamma-aminobutyric acid (GABA) receptor, rho 1.81 -1. 12 0 .29 0.73 23 .1 11.5 -1 .27 1 .24 0.53 0 .20 15 .2 21.9 23 4410_at ... immunohistochemistry in guinea pig trachea [22 ] Using specific agonists, GABA-B receptors coupling to G proteins in general and its specific coupling to the G protein was shown in a human airway epithelial ... 21 31 47 58 15/6 21 /10 33/14 38 /20 Age (yr) 41 ± 44 ± 42 ± 11 43 ± Race (B/W/O )2 10/7/4 20 /7/4 23 /18/6 35/14/9 n Sex (male/female) Smoking history (pack-yr) Healthy smokers 28 ±18 28 ± 17 Urine...
Ngày tải lên: 12/08/2014, 11:22
Báo cáo y học: "Enhancement of in vitro interleukin-2 production in normal subjects following a single spinal manipulative treatment" potx
... sixty-four subjects Spine 20 02, 27 :24 59 -24 66 Protopapas MG, Cyment TC: Joint cracking and popping: Understanding noises that accompany articular release J Am Osteopath Assoc 20 02, 1 02: 283 -28 7 Ross JK, ... ester-induced T-cell activation Accessory cell requirement for T-cell activation Scand J Immunol 1991, 33(4):393-403 22 24 25 26 27 28 29 30 31 32 33 34 35 36 Teodorczyk-Injeyan J, Ruegg R, Injeyan ... at 20 minutes No statistically significant difference in IL -2 secretion was found between the three groups (F = 0 .22 , p = 0.8 023 ), (Fig 2B) IL -2 synthesis in vivo Determinations of systemic (in...
Ngày tải lên: 13/08/2014, 14:20
Báo cáo y học: "Expression of novel extracellular sulfatases Sulf-1 and Sulf-2 in normal and osteoarthritic articular cartilage" pdf
... developed Sulf expression was also determined in murine knee joints Interestingly, Sulf expression was high at month of age and Figure Sulf-1 and Sulf -2 expression in specific zones of normal and ... cartilage Sulf-1 and Sulf -2 protein expression in normal and osteoarthritis (OA) cartilage Sulf protein expression in normal (43 years old; Mankin score: 2) and OA (79 years old; Mankin score: 9) cartilage ... and Sulf -2 protein bands migrated at approximately 72 kDa, which is the molecular mass of the secreted proteins [17,30,31] Sulf-1 and Sulf -2 expression in murine joints TM joints from normal C57BL/6J...
Ngày tải lên: 09/08/2014, 10:23
Tài liệu Báo cáo khoa học: Altered expression of CD1d molecules and lipid accumulation in the human hepatoma cell line HepG2 after iron loading pptx
... – saponin +saponin +saponin 20 40 60 80 100 Counts – saponin C Counts 20 40 60 80 100 Negative 100 101 1 02 103 104 100 101 1 02 103 104 Ferritin D 154 FEBS Journal 27 2 (20 05) 1 52 165 ª 20 04 FEBS ... and intracellular lipid content in HepG2 cells by examining phosphatidylserine expression and lipid droplet accumulation, respectively Phosphatidylserine is a FEBS Journal 27 2 (20 05) 1 52 165 ª 20 04 ... Journal 27 2 (20 05) 1 52 165 ª 20 04 FEBS M Cabrita et al CD1d upregulation in iron-loaded HepG2 cells A 10.0 +Fe 19.7 Nor3 .2 –Fe 19.8 22 .7 Annexin-V B Fig Alterations in lipid metabolism parameters in...
Ngày tải lên: 19/02/2014, 16:20
Báo cáo khoa học: Tyrosine nitration in the human leucocyte antigen-Gbinding domain of the Ig-like transcript 2 protein ppt
... 8009–8 022 22 Zhan X & Desiderio DM (20 06) Nitroproteins from a human pituitary adenoma tissue discovered with a ILT2 nitration in the binding domain 23 24 25 26 27 28 29 30 31 nitrotyrosine affinity ... Journal 27 6 (20 09) 423 3– 424 3 ª 20 09 The Authors Journal compilation ª 20 09 FEBS 423 7 ILT2 nitration in the binding domain ´ A Dıaz-Lagares et al Fig (Continued) 423 8 FEBS Journal 27 6 (20 09) 423 3– 424 3 ... Journal 27 6 (20 09) 423 3– 424 3 ª 20 09 The Authors Journal compilation ª 20 09 FEBS 424 1 ´ A Dıaz-Lagares et al ILT2 nitration in the binding domain 1.8 2. 2 kV MS ⁄ MS data were collected in an automated...
Ngày tải lên: 07/03/2014, 02:20
Báo cáo khoa học: Identification and characterization of B¢¢-subunits of protein phosphatase 2 A in Xenopus laevis oocytes and adult tissues Evidence for an independent N-terminal splice variant of PR130 and an extended human PR48 protein pot
... (PME-1) is one of several novel proteins stably associating with 17 18 20 21 22 23 24 25 26 27 two inactive mutants of protein phosphatase 2A J Biol Chem 27 4, 143 82 14391 Wu, J., Tolstykh, T., Lee, ... Chem 26 2, 1049– 1059 29 Wang, S.S., Esplin, E.D., Li, J.L., Huang, L., Gazdar, A., Minna, J & Evans, G.A (1998) Alterations of the PPP2R1B gene in human lung and colon cancer Science 28 2, 28 4 28 7 ... and coworkers [21 ] (see Table and Fig 2C) The human PR 72 protein is identical in its C-terminal part to human PR130, but has a totally different N-terminus Examination of the PPP2R3 A gene showed...
Ngày tải lên: 08/03/2014, 08:20
Báo cáo khoa học: Enzymes of mannitol metabolism in the human pathogenic fungusAspergillus fumigatus– kinetic properties of mannitol-1-phosphate 5-dehydrogenase and mannitol 2-dehydrogenase, and their physiological implications pot
... oxidized and reduced nicotinamide adenine dinucleotides Anal Biochem 1 42, 23 223 4 38 Klimacek M & Nidetzky B (20 02) Examining the relative timing of hydrogen abstraction steps during NAD+-dependent oxidation ... metabolism in wild-type, fructokinase-negative and revertant strains of Rhizobium leguminosarum J Gen Microbiol 130, 23 123 7 FEBS Journal 27 8 (20 11) 126 4 127 6 ê 20 11 The Authors Journal compilation ê 20 11 ... contributing to the substrate-binding site of PsM2DH are fully conserved in AfM2DH, explaining the observed substrate specicity of the A fumigatus enzyme [ 12, 20] It can be assumed from the way in which...
Ngày tải lên: 14/03/2014, 23:20
Báo cáo khóa học: Characterization of presenilin complexes from mouse and human brain using Blue Native gel electrophoresis reveals high expression in embryonic brain and minimal change in complex mobility with pathogenic presenilin mutations pptx
... (1 20 ) [20 ]; Ab 00/ and Ab 00 /2 PS1 loop (301–317) [21 ]; Ab 00/ 12, PS2 loop (307–336); Ab 00/19 NCT CT (691–709]) [22 ]; Ab 00 /22 NCT ectodomain (331–346); Ab 02/ 45 PEN -2 NT (1–15) and Ab 02/ 41 ... C.L (20 00) Presenilin expression in neuronal cells: induction during differentiation of embryonic carcinoma cells Exp Cell Res 25 5, 1 92 20 6 21 Evin, G., Sharples, R.A., Weidemann, A., Reinhard, ... Selkoe, D.J (20 03) Assembly of the gammasecretase complex involves early formation of an intermediate subcomplex of Aph-1 and Nicastrin J Biol Chem 27 8, 3 721 3–3 722 2 42 Steiner, H., Winkler, E.,...
Ngày tải lên: 16/03/2014, 16:20