Báo cáo y học: " APOBEC3G-UBA2 fusion as a potential strategy for stable expression of APOBEC3G and inhibition of HIV-1 replication" pot

... of mortality at 28-days or censoring at hospital discharge have logistic advantages but as many as one-third of critically ill patients may still be in hospital after 28 days and deaths can ANZICS: ... Australia 3 Clinical Associate Professor, School of Population Health, University of Western Australia, Stirling Highway, Crawley 6009, Australia 4 ANZICS CORE Group, Australian...

Ngày tải lên: 13/08/2014, 18:22

... concentration was determined spectro- photometrically [24]. PK activity was evaluated as a cell-age marker by the method of Beutler et al.[16]. Statistical analysis Statistical analysis was performed ... 2035 isomerization of aspartate residues [6]. Major targets of these alterations, also called Ôprotein molecular fatigue damageÕ [7], are cytoskeletal components, such as ankyrin...

Ngày tải lên: 08/03/2014, 22:20

... new treatment strategy that apparently acts upstream of the current treatment regimens employing cytokine blockage and that may be well suitable for a subset of patients. Identifying the mechanisms by which ... declared. Acknowledgements Supported in part by grants from the National Institutes of Health (AR 42457, AR 41974 and AI 44142) and by the Mayo Foundation. We thank J...

Ngày tải lên: 09/08/2014, 01:21

... ERAD system eliminates unfolded proteins that Commentary Rheumatoid arthritis as a hyper-endoplasmic reticulum- associated degradation disease Satoshi Yamasaki 1 , Naoko Yagishita 1 , Kaneyuki ... 41:1995-2003. 11. Amano T, Yamasaki S, Yagishita N, Tsuchimochi K, Shin H, Kawa- hara K, Aratani S, Fujita H, Zhang L, Ikeda R, et al.: Synoviolin/Hrd1, an E3 ubiquitin ligase, as a novel pa...

Ngày tải lên: 09/08/2014, 07:20

... as a cytoplasmic actin-regulatory protein essential for cell locomotion and phagocytosis. When a circulating isoform was subsequently discovered, its physio- logical significance was far from apparent. For ... the sequestration hypothesis, as long as the isoform associated with the complexes is plasma gelsolin. Rheumatoid arthritis represents a chronic inflammatory state pun...

Ngày tải lên: 09/08/2014, 13:22

... longitudinal analysis of urinary TWEAK (uTWEAK) and/ or serum TWEAK (sTWEAK) levels as potential biomarkers of LN. The performance of TWEAK as a biomarker for nephritis was compared with routinely used ... study, although uTWEAK levels did increase as the flare approached, the peak was at the time of the flare rather than in advance of it. As the measurements were bas...

Ngày tải lên: 09/08/2014, 14:22

... this article as: Siriwardana et al.: Toxoplasmosis presenting as a swelling in the axillary tail of the breast and a palpable axillary lymph node mimicking malignancy: a case report. Journal of ... presenting as a swelling in the axillary tail of the breast and a palpable axillary lymph node mimicking malignancy: a case report HP Priyantha Siriwardana 1* , Louise Te...

Ngày tải lên: 10/08/2014, 23:22

... 99:501-505. doi:10.1186/1752-1947-5-118 Cite this article as: Seth and Seth: Axial torsion as a rare and unusual complication of a Meckel’s diverticulum: a case report and review of the literature. Journal of Medical Case Reports ... patient had normal renal function and a normal hemoglobin level. An abdominal radiograph revealed dilated small bowel loops, and a c...

Ngày tải lên: 11/08/2014, 00:23

... serve a variety of formal and informal roles [44]. Analysis of 82 articles published from 1977 to 1994 found that nursing mentorship was associated with greater job satisfaction and academic achievement ... outcomes, and factors influencing mentorship therefore a conceptual framework was derived to inform data collection and analysis (Figure 1). This was based on a review by...

Ngày tải lên: 11/08/2014, 05:21

... S, Fukamachi H, O'Reilly LA, Kuida K, Strasser A: Transforming growth factor beta-dependent sequential acti- vaiton of Smad, Bim, and caspase-9 mediates physiological approaches in gastric ... membrane potential, may have increased levels of cell surface MHC, are easily damaged by free radicals (including excessive reactive oxygen intermediates), and may show increased levels...

Ngày tải lên: 11/08/2014, 10:23