Báo cáo y học: " APOBEC3G-UBA2 fusion as a potential strategy for stable expression of APOBEC3G and inhibition of HIV-1 replication" pot
Báo cáo y học: " Landmark survival as an end-point for trials in critically ill patients – comparison of alternative durations of follow-up: an exploratory analysis" doc
... of mortality at 28-days or censoring at hospital discharge havelogistic advantages but as many as one-third of critically illpatients may still be in hospital after 28 days and deaths canANZICS: ... Australia3Clinical Associate Professor, School of Population Health, University of Western Australia, Stirling Highway, Crawley 6009, Australia4ANZICS CORE Group, Australian and New Zealand ... cohort may be reasonably representa-tive of other Australian ICU populations. The ICU practices and post acute hospital care across Australia are similar. Aus-tralian ICU practice and outcomes are...
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Báo cáo Y học: Protein methylation as a marker of aspartate damage in glucose-6-phosphate dehydrogenase-deficient erythrocytes docx
... concentration was determined spectro-photometrically [24].PK activity was evaluated as a cell-age marker by themethod of Beutler et al.[16].Statistical analysisStatistical analysis was performed ... 2035isomerization of aspartate residues [6]. Major targets of these alterations, also called Ôprotein molecular fatiguedamageÕ [7], are cytoskeletal components, such as ankyrin and bands 4.1 and 4.2, as ... slice[6,9]. Radioactivity was expressed as d.p.m./band area.Determination of AdoMet and S-adenosylhomocysteineintracellular contentIntracellular concentrations of AdoMet and S-adenosyl-homocysteine...
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Báo cáo y học: "B cells as a therapeutic target in autoimmune disease" doc
... newtreatment strategy that apparently acts upstream of thecurrent treatment regimens employing cytokine blockage and that may be well suitable for a subset of patients.Identifying the mechanisms by which ... declared.AcknowledgementsSupported in part by grants from the National Institutes of Health (AR42457, AR 41974 and AI 44142) and by the Mayo Foundation. Wethank James W Fulbright for assistance ... in the treatment of a variety of autoimmune syndromes, including systemiclupus erythematosus (SLE), rheumatoid arthritis (RA), and vasculitic syndromes. Plasmapheresis still has anaccepted role...
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Báo cáo y học: "Rheumatoid arthritis as a hyper-endoplasmic reticulumassociated degradation disease" pdf
... ERAD system eliminates unfolded proteins thatCommentaryRheumatoid arthritis as a hyper-endoplasmic reticulum-associated degradation diseaseSatoshi Yamasaki1, Naoko Yagishita1, Kaneyuki ... 41:1995-2003.11. Amano T, Yamasaki S, Yagishita N, Tsuchimochi K, Shin H, Kawa-hara K, Aratani S, Fujita H, Zhang L, Ikeda R, et al.:Synoviolin/Hrd1, an E3 ubiquitin ligase, as a novel pathogenicfactor for ... Nishioka2 and Toshihiro Nakajima11Department of Genome Science, Institute of Medical Science, St Marianna University School of Medicine, Kawasaki, Kanagawa, Japan2Rheumatology, Immunology and...
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Báo cáo y học: "Plasma gelsolin as a biomarker of inflammation" doc
... as a cytoplasmic actin-regulatory proteinessential for cell locomotion and phagocytosis. When a circulating isoform was subsequently discovered, its physio-logical significance was far from apparent. For ... thesequestration hypothesis, as long as the isoform associatedwith the complexes is plasma gelsolin.Rheumatoid arthritis represents a chronic inflammatory statepunctuated by episodes of acute synovitis. ... Identified ligands include platelet-activating factor, lysophosphatidic acid, and sphingosine 1phosphate, as well as cell-wall constituents of Gram-negative and Gram-positive bacteria [6-8]. Actin...
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Báo cáo y học: "Urinary TWEAK as a biomarker of lupus nephritis: a multicenter cohort study" potx
... longitudinal analysis of urinary TWEAK (uTWEAK) and/ orserum TWEAK (sTWEAK) levels as potential biomarkers of LN.The performance of TWEAK as a biomarker for nephritis wascompared with routinely used ... study, although uTWEAK levels didincrease as the flare approached, the peak was at the time of the flare rather than in advance of it. As the measurementswere based on a relatively small group of ... were available, to examine the relation-ship between uTWEAK levels and disease activity over time.Classification of systemic lupus erythematosus activity statusLN activity was evaluated based...
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Báo cáo y học: " Toxoplasmosis presenting as a swelling in the axillary tail of the breast and a palpable axillary lymph node mimicking malignancy: a case report" potx
... this article as: Siriwardana et al.: Toxoplasmosis presenting as a swelling in the axillary tail of the breast and a palpable axillary lymphnode mimicking malignancy: a case report. Journal of ... presenting as a swelling in theaxillary tail of the breast and a palpable axillarylymph node mimicking malignancy: a case reportHP Priyantha Siriwardana1*, Louise Teare2, Dia Kamel3 and E ... cases have been reported [3-5]. We present a case of toxoplasmosis that presented as an axillary tail(breast) mass and a palpable axillary lymph node whichmimicked breast cancer.Case presentationA...
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Báo cáo y học: " Axial torsion as a rare and unusual complication of a Meckel’s diverticulum: a case report and review of the literature" ppsx
... 99:501-505.doi:10.1186/1752-1947-5-118Cite this article as: Seth and Seth: Axial torsion as a rare and unusualcomplication of a Meckel’s diverticulum: a case report and review of the literature. Journal of Medical Case Reports ... patient had normal renalfunction and a normal hemoglobin level. An abdominalradiograph revealed dilated small bowel loops, and a clinical diagnosis of perforated acute appendici tis wasmade. ... fibroma,hemangioma, neurofibroma, carcinoid tumor, adenocar-cinoma, fibrosarcoma, and leiomyosarcoma [11]. Benignlesions within MD, such as lipomas, have also beenrecognized as a potential cause...
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Báo cáo y học: " Exploring mentorship as a strategy to build capacity for knowledge translation research and practice: protocol for a qualitative study" pps
... serve a variety of formal and informal roles[44]. Analysis of 82 articles published from 1977 to 1994found that nursing mentorship was associated withgreater job satisfaction and academic achievement ... outcomes, and factors influencing mentorshiptherefore a conceptual framework was derived to informdata collection and analysis (Figure 1). This was based on a review by Karcher of the educational and ... JE, Tait N, etal.: Surgical management of invasive breast cancer: a 5-yearprospective study of treatment in the Australian CapitalTerritory and South-Eastern New South Wales. ANZ J Surg2005,...
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Báo cáo y học: "Cellular metabolism as a basis for immune privilege" pps
... S, Fukamachi H, O'Reilly LA, Kuida K, Strasser A: Transforming growth factor beta-dependent sequential acti-vaiton of Smad, Bim, and caspase-9 mediates physiologicalapproaches in gastric ... membrane potential, may have increased levels of cell surface MHC,are easily damaged by free radicals (including excessivereactive oxygen intermediates), and may show increasedlevels of cell ... mitochondrialmembrane potential, are less likely to express cell surfaceMHC molecules, are less easily, or are more resistant to,damage caused by free radicals, and have relatively lowerlevels of co-stimulatory...
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