Báo cáo khoa học: "Statins, bugs and prophylaxis: intriguing possibilities" pptx

... care systems and to governments eager to avoid the potential human and economic consequences of large-scale infection and death. As things stand, the world is ill-prepared for a pandemic. Current ... several scientific and clinically important questions. Do statins present a potential preventive and/ or supplementary treatment for seasonal influenza and for the expected influenza p...

Ngày tải lên: 13/08/2014, 03:20

... events A and B corefer, and there is a link between A and time expression t, then there is also a link between B and t. This was not explicitly expressed in the data. For the task at hand, we ... systems. Our work is similar to that of Boguraev and Ando (2005), whose research only deals with temporal links between events and time expres- sions (and does not consider relations at...

Ngày tải lên: 24/03/2014, 03:20

... time courses and effects of unlabeled ligands and low pH on the dissociation rates of [ 125 I]TC-PCSK9 (A) and [ 125 I]TC-PCSK9-D374Y (B) from HepG2 cells. Binding to equilibrium and removal of ... HepG2 cells (70 000, 140 000 and 280 000) were seeded in 12-well plates and incubated either for 48 h in complete growth medium or for 24 h in com- plete growth medium, and then for 2...

Ngày tải lên: 14/02/2014, 14:20

... PcrH and IpgC are shown in yellow, green and magenta, respec- tively. The peptides located within the concave regions of PcrH and IpgC, corresponding to sections of the N-termini of PopD and IpaB, ... levels (i.e. 38% for Pseudomonas PopD and Yersinia YopD; 29% for Shi- gella IpaC and Salmonella SipC). Indeed, sections of IpaC and SipC (as well as YopD and PopD) are inter- cha...

Ngày tải lên: 14/02/2014, 22:20

... t-bet, stat6 and foxp3 were also determined and found to be very simi- lar to their human homologues. Both the human and zebrafish T-bet and Foxp3 genes contained the same number of exons and introns. ... in the lung tissue of mouse and spleen and thymus of human and mouse [11,37]. Foxp3 is also highly expressed in lymphoid organs, such as the thymus and spleen [49], and it...

Ngày tải lên: 16/02/2014, 09:20

... liver and WAT. Paraffin sections of liver and WAT from WT and TG mice (S55) were stained with antibody against human H-PGDS. Bars: 100 lm. (D) PGDS activity in liver of WT and S41, S55 and S66 ... family, and is also called GSTS1 [17]. On the other hand, L-PGDS has been purified from rat brain [18], and is expressed in brain, heart, and male genital organs, as well as in adipocy...

Ngày tải lên: 16/02/2014, 09:20

... and ubiquitin C-terminal hydrolase (specific markers for neural and neuroendocrine tissues) were found in rat long bones at embryonic day 15, in the diaphyseal and metaphyseal perichondrium, and ... adrenergic and cholinergic in nature, and originate from paravertebral sympathetic ganglia [16]. Experimental nerve deletion and immunohisto- chemistry analysis have shown that both m...

Ngày tải lên: 18/02/2014, 04:20

... NADPH and MSR 1.12 ± 0.04 With NADPH and CPR 0.09 ± 0.02 With NADPH and nNOSred 0.18 ± 0.02 MeCbl Without MSR or NADPH 0.06 ± 0.01 With MSR 1.23 ± 0.15 With FMN domain 1.20 ± 0.10 With NADPH and ... radioactivity in the flowthrough and wash fractions was quantitated by scintillation counting. For MSR-catalysed assays (used for measuring the K m of NADPH and the K act of MSR), AqCbl...

Ngày tải lên: 18/02/2014, 08:20

... 1D). GmPDIL-3a and GmPDIL-3b have two predicted thioredoxin domains between amino acids 65–164 and 403–481, and 68–167 and 406–508, respectively, corresponding to the a-domain and a¢-domain of ... and density (gÆmL )1 ) is indicated on the top. (B) Microsomes were treated without (lanes 1 and 2) or with (lanes 3 and 4) proteinase K, in the absence (lanes 1 and 3) or presence...

Ngày tải lên: 18/02/2014, 11:20

... cholesterol levels strictly and partially determine SREBP-2 and SREBP-1 cleav- age in mammalian cells for sterol regulation and synthesis of other lipids, respectively. Intriguingly, cleavage of ... elevated, and consequently, the levels of nuclear SREBP-1c protein and lipogenesis are enhanced in the liver and adipose tissues. Intake of energy molecules such as sugars, carbohydrat...

Ngày tải lên: 18/02/2014, 13:20