Báo cáo y học: "Corticosteroids influence the mortality and morbidity of acute critical illnes" pot

... content. MYR had full access to all of the data in the study and takes responsibility for the integrity of the data and the accuracy of the data analysis. All authors read and approved the final ... immune response in the critically ill [1]. Early use of corticosteroids has been recommended in sepsis, acute lung injury, acute respira- tory distress syndrome...

Ngày tải lên: 13/08/2014, 01:20

... University of Ulm, Germany, USA; David J Miklowitz, Professor of Psychology and Psychiatry, Department of Psychology, University of Colorado, USA; Jefferson Prince, Instructor in Psychiatry, Massachusetts ... polycystic ovary syndrome and bipolar disorder: The endophenotype hypothesis. Med Hypotheses 2009. 69. Choonara I, Conroy S: Unlicensed and off-label drug use in children...

Ngày tải lên: 13/08/2014, 18:21

... generally affected by chemotherapy and radiation therapy. Using various statistical approaches, the genetic association between SNPs in genes involved in the ROS pathways and the expression levels of ... study revealed that the DNA composition of CpG islands, the sequence, the structure and the number of repeats play an important role in predisposing CpG islands to D...

Ngày tải lên: 14/08/2014, 17:22

... slightly larger than the 80-kDa oviduct enzyme, the two ecto-ATPDases are nearly identical with respect to their enzymatic properties and mass of the deglycosylated proteins. The primary sequence of ... ATPase activity at either pH 7.4 or pH 6.4 (Fig. 3). At pH 7.4, 5m M azide inhibited ADP hydrolysis by  70% whereas ATP hydrolysis was inhibited by only 10%. Inhibition of ADP...

Ngày tải lên: 22/02/2014, 04:20

... even in the absence of their relevant cytokine ligands in the plasma membrane of T lymphoma cells. Binding of the physiological ligands (IL-2, IL-7, IL-15) was reported to selectively mod ulate the ... superfamily, and their intracellular trafficking is different from that of the b and c c chains [7]. It is still not clear whether the assembly of the high affinity IL...

Ngày tải lên: 17/03/2014, 23:20

... with the comple- ment system dysfunction, including hyperactivation state of the complement classical pathway, hypoactivation state of the complement alternative pathway and overac- tivation of the ... hypoactivation of the complement alternative pathway and overactivation of the terminal pathway. Conclusions: The results obtained provide further evidence on the...

Ngày tải lên: 08/08/2014, 21:20

... (the ASAS20, ASAS40, and ASAS partial remission criteria, respectively) of clinical symptoms. Andrei Calin, of Bath, UK, had started this kind of work in the early 90s with the definition of the ... efficacy on signs and symptoms, there is evidence that continuous therapy with NSAIDs might stop the new formation of syndesmophytes in the spine, as reported recently [28...

Ngày tải lên: 09/08/2014, 01:22

... only the past few years after their common genetic aetiology was discovered. Clinical disease is accompanied by an acute- phase response and often leukocytosis and thrombocytosis and anaemia of chronic ... periodic syndrome (TRAPS), the hyper-IgD and periodic fever syndrome (HIDS), and the cryopyrin-associated periodic syndrome (CAPS) and acquired diseases of adult- hoo...

Ngày tải lên: 09/08/2014, 01:22

... examined the mode of action of MTX. It acts as an antagonist of folic acid, subsequently inhibiting the synthesis of purines and pyrimidines. It was further sug- gested that the anti-inflammatory effect ... study the legs were removed up to the knees, fixed in 10% formaldehyde, decalcified, dehydrated, paraffin embedded and cut into 4 μm sections. They were then stained...

Ngày tải lên: 09/08/2014, 08:23

... therapeutic strategy. They can inhibit the activity and production of MMPs (MMP-1, MMP-3 and MMP-13, and MMP-2 and MMP-9). This family of agents includes tetracycline, doxycycline, minocycline and the tetracycline ... astacins, the adamalysins, the MMPs and the pappalysins [5]. The family of MMPs is best known for its ability to cleave components of the ECM,...

Ngày tải lên: 09/08/2014, 10:21