... analysis, anatomopathological anal-ysis and drafted the manuscript. JQ carried out the anato-mopathological analysis and helped to design the study.EEB participated in design and coordination ... use hypoxia, up to death in mice,starting at an age when they naturally start dying, in orderto evaluate long-term positive or negative survival effects of hypoxic PH and a potential therapy. ... Circulation 2001,104:424-428.22. Nakanishi K, Tajima F, Osada H, Nakamura A, Yagura S, Kawai T,Suzuki M, Torikata C: Pulmonary, vascular responses in ratsexposed to chronic hypobaric hypoxia at...