Báo cáo khoa học: "Tezosentan-induced attenuation of lung injury in endotoxemic sheep is associated with reduced activation of protein kinase " doc
Báo cáo khoa học: "Tezosentan-induced attenuation of lung injury in endotoxemic sheep is associated with reduced activation of protein kinase " doc
... http://ccforum.com/content/9/3/R211
R211
Vol 9 No 3
Research
Tezosentan-induced attenuation of lung injury in endotoxemic
sheep is associated with reduced activation of protein kinase C
Vladimir Kuklin
1
, Mikhail Kirov
1
, Mikhail ... mechanisms
involved have not yet been settled [14].
Studies in vitro have shown that the binding of ET-1 to its
receptor migh...
Báo cáo khoa học: Cellular refractoriness to the heat-stable enterotoxin peptide is associated with alterations in levels of the differentially glycosylated forms of guanylyl cyclase C pdf
... domain protein which interacts with GC-C was
identified in a yeast two hybrid screen [44]. This protein
named Ôintestine and kidney-enriched PDZ protein
(IKEPP) interacts with GC-C through one of ... then incubated overnight with
5 lgÆmL
)1
GC-C:4D7, an antibody raised to the protein
kinase- like domain of GC-C [32] or with GC-C:4D7
antibody preadsorbed with a fusion...
Báo cáo y học: "Early drotrecogin alpha (activated) administration in severe sepsis is associated with lower mortality: a retrospective analysis of the Canadian ENHANCE cohort" ppsx
... the incidence of
severe sepsis is steadily increasing, the total number of deaths
continues to increase [1-3].
In the setting of severe sepsis, early multi-modal, goal-directed
therapy including ... with sepsis-induced organ dys-
function who meet criteria for its administration. However,
delays in initiating treatment with DrotAA in Canada are com-
mon – in a registry of...
Báo cáo y học: "Norepinephrine to increase blood pressure in endotoxaemic pigs is associated with improved hepatic mitochondrial respiration" doc
... haemodynamic effects. This
is in contrast to our findings in septic pigs, in which norepine-
phrine was associated with an increase in the hepatic lactate
influx with no concomitant increase in the hepatic ... balance with norepinephrine. Only one study evaluated
the effects of increasing MAP from 65 to 85 mmHg using
norepinephrine [22]. In this study, conducted in 1...
Báo cáo khoa học: " Mechanical ventilation and lung infection in the genesis of air-space enlargement" pptx
... regional distribution found in piglets
is very similar to the distribution of lung overinflation reported
in patients in the early stage of ARDS: in the supine position,
Figure 1
Severity of lung infection ... distributed in
non-dependent lung regions with persisting lung aeration. In
ventilated-inoculated piglets, lung infection involved more than
two thirds...
Báo cáo khoa học: Biochemical evidence for conformational changes in the cross-talk between adenylation and peptidyl-carrier protein domains of nonribosomal peptide synthetases ppt
... active-site histidine
of the C-domain is 16 A
˚
, making it within the reach of
the missing Ppant arm (capable of reaching 20 A
˚
dis-
tance at full linear extension). However, the distances
to ... (achieved by binding
of an inhibitor) affects the relative conformation of the
in cis interacting PCP domain. It is conceivable that
most of this change is coordinated through a...
báo cáo khoa học: "Fulminant Leptospirosis (Weil’s disease) in an urban setting as an overlooked cause of multiorgan failure: a case report" pptx
... risk for contracting
leptospirosis, the patient admitted to having be en in con-
tact with rat urine with his bare hands at a construction
site in NYC.
Discussion
Leptospirosis is a zoonosis of ... bilirubin of 2.6 mg/dL,
alkaline phosphatase (ALP) of 143 U/L, aspartate amino-
transferase (AST) of 201 U/L, alanine aminotransferase
(ALT) of 246 U/L, and creatine kinase o...
Báo cáo khoa học: "Clinical review: Independent lung ventilation in critical care" doc
... left lung is unreliable. The
auscultation method can result in incorrect positioning in
38% of cases, with wrong main stem intubated in 20.8% and
double-lumen tube above the carina in 38.7% of ... transplant for COPD include severity of
underlying airway obstruction, peri-operative injury to the
donor lung and size of donor lung [60].
Bronchopleural fistula
Interco...
Báo cáo khoa học: "Clinical review: Bedside lung ultrasound in critical care practice" ppsx
... disease, lung sliding
can be abolished in the absence of pneumothorax. The
diagnosis remains uncertain in patients with normal lung
aeration whereas in patients with lung injury, the presence of
vertical ... lung sliding and absence of lung sliding may
coexist in lateral regions of the chest wall. In this boundary region,
called the lung point’ (P), lung sl...
Báo cáo khoa học: A novel antifungal hevein-type peptide from Triticum kiharae seeds with a unique 10-cysteine motif doc
... the 43-amino acid chitin-binding peptide isolated
from the rubber tree Hevea brasiliensis [12], and com-
prise the single hevein domain subfamily in a large
group of chitin-binding proteins [13–16] ... chitin-
binding domain, which is responsible for binding the
carbohydrate. In addition to hevein, the members of
this family are lectins, chitinases, some wound-induced
proteins and a...
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