intensive insulin therapy in critically ill patients

... Continuous infusion of vancomycin is increasingly preferred as an alternative to intermittent administration in critically ill patients. Intermittent vancomycin treatment is associated with an increased occurrence ... between obtain ing therapeutic serum levels and avoiding nephrotoxicity during continu- ous vancomycin infusion in critically ill patients with severe Gram-positi...

Ngày tải lên: 21/06/2014, 01:20

... Whereas colistin is mainly administered i.v. in critically ill patients, it can be safely be administered by inhalation in patients with pneumonia/VAP or intrathe- cally in patients with meningitis ... topical administra- tion of colistin is noted in approximately 15% of patients. Colistin’s clinical efficacy in critically ill patients In a recently published stud...

Ngày tải lên: 21/06/2014, 01:20

... of developing acute kidney injury (AKI) during continuous vancomycin infusion remains poorly examined, especially in the critically ill. Vanco- mycin pharmacodynamics in this population is chal- lenged ... therapeutic serum levels and avoiding nephrotoxicity during continu- ous vancomycin infusion in critically ill patients with severe Gram-positive infections and normal baseli...

Ngày tải lên: 21/06/2014, 02:20

... reported to increase renal blood flow, urine out- put, and creatinine clearance in experimental sepsis [38]. Although norepinephrine also has been found to increase creatinine clearance in human ... clinical studies in which MAP was increased with norepinephrine have provided conflicting results. Bourgoin et al. found that increasing MAP from 65 to 85 mmHg did not further improve creati...

Ngày tải lên: 21/06/2014, 03:20

... acute CMS-induced kidney injury: male sex, concomitant use of a calcineurin inhibitor, hyperbilirubi- nemia, and hypoalbuminemia. The incidence of kidney injury increased with an increase in the ... creatinine and GFR criteria) Category Criteria Risk (R) Increased creatinine level × 1.5 or GFR decrease >25% Injury (I) Increased creatinine level × 2 or GFR decrease >50% Failure (F) Inc...

Ngày tải lên: 21/06/2014, 03:20

... same results were obtained for invasive routine monitoring in all 43 patients (data not shown). Circulating Ang-2 predicts mortality in critically ill patients To determine the relation between ... early feature in critically ill patients, but might reflect ongoing illness, as is often the case in medical patients compared with sudden onset of impairment in surgical a...

Ngày tải lên: 25/10/2012, 10:31

... den Berghe G., et al. Intensive insulin therapy in critically ill patients. N Engl J Med, 2001. 345:1359-67. 53. Choi K.W., et al. Outcomes and prognostic factors in 267 patients with severe ... uncertain. Tracheostomy is required in patients requiring prolonged mechanical ventilation and ICU stay. Strict adherence to infection control guidelines is mandatory in pe...

Ngày tải lên: 03/11/2012, 10:20

... below). Articles in Annals of Intensive Care are listed in PubMed and archived at PubMed Central. For information about publishing your research in Annals of Intensive Care go to http://www.annalsofintensivecare.com/authors/instructions/ For ... resources and training 1) Initial and regular training is mandatory for all staff providing IHT, both in the use of equipment and its m...

Ngày tải lên: 21/06/2014, 17:20

... combined in a model, could discriminate the treating rheumatologist's decision to give a dose increase of infliximab to RA patients not optimally responding to an indicated dose of 3 mg infliximab ... systemic inflammation. Infliximab, in combination with methotrexate (MTX), is a highly effective therapy for a majority of RA patients. After an induc- tion scheme at weeks 0, 2 an...

Ngày tải lên: 09/08/2014, 06:23

... in disease activity was observed over the remaining 3.5 years. This decrease in disease activity was observed in both the patients who continued with infliximab therapy and those who discontinued ... findings also indicate that the decision to continue infliximab therapy is best made using the DAS28 score. Competing interests The study was supported by a grant from Centocor BV and...

Ngày tải lên: 09/08/2014, 08:22