the value of muscle exercise in patients with als

... presence of DM were the independent predictors of CVD in the earlier stages of CKD (Table 4). Table 1: Characteristics of patients with CKD stage II to IV excluding patient with history of renal ... Results were reported as p values and Odds Ratios with 95% confidence intervals. All analyses were conducted with the use of STATVIEW software. RESULTS The patients included 52% male and 48% ... S. Albumin: 0.0365 0.554 (0.391-0.962) DISCUSSION The majority of patients with CKD have severe manifestations of CVD by the time they need mainte- Int. J. Med. Sci. 2008, 5 366 International...

Ngày tải lên: 03/11/2012, 11:52

... organ involved, all of them were counted independently; � , 2 patients with intestinal TB diagnosed based on typical colonosopic findings and the other 2 patients with TB laryn- gitis without ... extrapulmonary involvement in the elderly could result from the small number of patients older than 60 yr (61 patients, 19.1%) in this study. In this setting, a small change in the number of patients with ... higher in the elder- ly (28). In addition, the lower risk of EPTB in the elderly does not support immunity as a determinant of the spread of tuberculous bacilli to other organs because of the higher incidence...

Ngày tải lên: 15/03/2014, 03:20

... an audit of financial statements in accordance with the ISAs. These additional responsibilities are not dealt with in the ISAs. They may be dealt with in the pronouncements of the International ... scope of the ISA, including how the ISA relates to other ISAs. • The subject matter of the ISA. • The respective responsibilities of the auditor and others in relation to the subject matter of ... example, assessing the reasonableness of the estimates made by management in preparing the financial statements. A24. The distinguishing feature of the professional judgment expected of an auditor...

Ngày tải lên: 29/03/2014, 18:20

... neuroserpin decrease. All determinations were carried out in a laboratory blind to the clinical outcome and neuroimaging findings. Endpoints The primary endpoint was the decrease of neuroserpin levels ... a total of 129 patients were finally included in the st udy. This research was carried out in accordance with the Declaration of Helsinki of the World Medical Associa- tion (2000) and approved by the ... Neuroserpin was used as a continuous variable since there was a linearity of the odds ratios for outcome. T he influence of neuroserpin decrease at 24 h on serum levels of molecular markers of brain injury...

Ngày tải lên: 18/06/2014, 19:20

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Ngày tải lên: 20/06/2014, 04:20

... 1 2-D pattern of the silver stained gel image of the master gel image. 2-D pattern of the silver stained gel image of a master gel image containing the spot information of all investigated samples. ... accumulation of genetic defects [25,26]. Interestingly, there were only marginal differences in the expression profiles comparing patient to patient. This was also observed in studies with patients with ... [27]. Expression of the plasminogen activator inhibitor-2 (PAI- 2) was only found in patients E and F with the subtyp FAB M0 and M4, respectively. This finding is inline with data from the PAI-2 serum...

Ngày tải lên: 18/06/2014, 15:20

... study. Other approaches for introducing IL2 into the tumor environment include injection of the cytokine intratumorally [17] and administering intratu- moral injections of adenovirus encoding IL2 ... patients in GD2 staining on melanoma cells and increases in staining for S100. Whether this decrease in GD2 staining intensity represents antigen downregulation versus steric hindrance from the ... purposes) immune-activating cytokines over the first 3 days of each treatment cycle. Our results show an increase in serum lev- els of sIL2R, IL10, and neopterin post-dosing. These find- ings may suggest the induction...

Ngày tải lên: 18/06/2014, 15:20

... participated in the design of the study and performed the statistical analysis and interpretation of data, and drafted the manuscript; ML participated in the design of the study and the statistical ... was involved in revising the manuscript critically for important intellectual content; SV made substantial contributions to the acquisition of the data, was involved in drafting and revising the ... ion of utility values, rather than a single imputation as performed here. Furthermore, the ability to predict the SF-6D and EQ- 5D from the HAQ is complicated by the weighting of items in the...

Ngày tải lên: 18/06/2014, 19:20

... sizes of trials and to make treatment decisions without the understanding that the point estimate of 1.5 is the best estimate of the minimal important difference and that the limits of the CIs ... linear regression analysis where the instrument of interest is the dependent and the anchors the independent variable. Using the equation one can estimate the minimal important difference of the ... important difference of the HADS it is not known[11] The concept of the minimal important difference the smallest difference in the outcome of interest that informed patients or their proxies perceive...

Ngày tải lên: 18/06/2014, 19:20

... improvements in all SF-36 scales, the greatest baseline to endpoint improvements (range of trial durations: 10 to 16 weeks) were seen in the Bodily Pain and Social Function scales. These findings are also ... by clinicians and patients [2]. The objective of this secondary analysis was to evaluate the effect of adalimumab on initial improvement in HRQOL for patients with psoriasis compared with the general ... evaluating the effect of adalimumab in patients with psoriasis (N = 1,205). Patients with moderate to severe psoriasis were randomized in a 2:1 ratio to adalimumab 80 mg (two 40 mg injections administered...

Ngày tải lên: 18/06/2014, 19:20

... and the other 37 patients lost between 10 and 27 letters). Analyses com- paring subgroups of patients with different levels of vision loss within this group of patients could help identify whether ... signifi- cantly associated with the VFQ-25 scales in any of the models. Comparing change in individual VFQ-25 items among the five ETDRS change groups Mean change in each individual item of the VFQ-25 was computed ... this link over time. Thus, the purpose of the current study was to examine the degree of change in HRQL that is associated with visual acuity changes among patients with diabetic retinopathy. Patients...

Ngày tải lên: 18/06/2014, 19:20

... patients were defined. In the absence of published thresholds, the following groups of patients were defined based on the distribution of the changes in both the weekly sleep inter- ference and pain diaries ... an 11-point numeric self-administered rating scale ranging from 0 (no pain) to 10 (worst possible pain). At the end of the baseline phase, a mean of the daily pain scores was calculated; patients with ... how their neuropathic pain had interfered with their sleep. It consists of a single-item with an 11-point numerical rating scale, ranging from 0 (pain does not interfere with sleep) to 10 (pain...

Ngày tải lên: 18/06/2014, 19:20

... pain rating of > 2 on an 11-point numerical rating scale (NRS) to enable enroll- ment of individuals with a broad range of pain severity, since another outcome of this study was validation of ... evaluated with the domains that are assessed by the MOS-SS. The psychometric properties of the MOS-SS have been evaluated in patients with a variety of conditions charac- terized by pain including ... There- fore, the purpose of this study was to evaluate the test- retest reliability of a one-week recall period of the MOS-SS compared with the four-week recall period in patients with FM. Methods The...

Ngày tải lên: 18/06/2014, 19:20