Báo cáo y học: "Erythropoietin in the critically ill – is it more than just blood" ppt

... benefit with EPO administration in the critically ill is clearly of interest, the difficulties involved in conducting clinical studies to test the hypothesis should not be underestimated. The ... and raise the intriguing possibility of clinical use of EPO to ‘protect’ tissues in the critically ill. Apoptosis is important in the pathogenesis of many critical il...

Ngày tải lên: 12/08/2014, 20:20

... Arthritis Research & Therapy, in which they describe cytokine patterns of inflamed joints from patients with Behçet’s disease (BD). The authors show that neutrophils and T lymphocytes are involved ... Steroids were contraindicated because of a previous retinal serosal ablation, probably induced by prednisone. TNF blockage initially successfully reduced the severity of the colitis,...

Ngày tải lên: 09/08/2014, 14:22

... response of different individuals to injury, surgery, infection, or sepsis that determines their ability or inability to recover from the onslaught of the initial event. The variations in neutrophil ... which is somewhat similar to the development of insulin resistance in patients only when they are ill but not before illness. This suggests that there are some very clear biolo...

Ngày tải lên: 12/08/2014, 18:21

Ngày tải lên: 12/08/2014, 18:21

... distinguished from noncritically ill patients with varying haemoglobin concentrations. Exogenous EPO therapy is unlikely to be effective in the first few days of critical illness. Keywords acute renal ... elevated in the initial phase of critical illness with ARF. In the chronic phase of critical illness, EPO levels are the same for patients with and those without ARF, and c...

Ngày tải lên: 12/08/2014, 19:22

... electron transfer activity is not maintained by the neighbouring tyrosine, while the W121F /Y1 22F mutant activity may be viewed as a commitment of the tyrosine residue to support the (somewhat higher) ... cytochrome c to any large extent, nor is this position involved in maintaining the low residual activity when the W121 residue is mutated. Double mutants in both posit...

Ngày tải lên: 22/02/2014, 07:20

... apparent binding affinity (K d ) for the large lipid particles, are notably distinct in their maximum binding capacities (Table 2). In particular, the binding footprint for the apoE4 isoform, corresponding ... [4 7–5 0]. This raises the possibility that any one or a combination of these properties may in uence the binding of apolipoproteins to lipoprotein particles. The capa...

Ngày tải lên: 08/03/2014, 09:20

... rhinosinusitis. Table 1 Classification of Chronic Rhinosinusitis Recurrent acute rhinosinusitis Chronic purulent rhinosinusitis Chronic hyperplastic rhinosinusitis Chronic rhinosinusitis with ... with diffuse sinonasal polyposis with polyps projecting into or com- pletely occluding the nasal airway (CRS with polyposis). However, the prognostic implica- tions of such distinctions remain ....

Ngày tải lên: 08/08/2014, 20:23

... assays, sheep erythrocytes sensitized with rabbit anti-sheep erythrocyte antibodies were used as target cells. The hemolytic activity was expressed in units/ml. One unit of hemolytic activity is defined ... protein C3 is the initial point of the alternative pathway,and,atthesametime,aconvergepointofall three complement activation pathways, i.e. starting point for the terminal pa...

Ngày tải lên: 08/08/2014, 21:20

... provided new insights into how OA may be successfully managed. The symptoms of osteoarthritis: pain and instability The pain of OA is activity-related, with pain coming on generally only when a person ... which there is little, if any, effective treatment. It accounts for more mobility disability in the elderly than any other disease. Symptomatic knee OA affects roughly 12%...

Ngày tải lên: 09/08/2014, 01:22