Báo cáo khoa học: "Intravenous colistin in the treatment of sepsis from multiresistant Gram-negative bacilli in critically ill patient" ppsx

... creatinine at initiation of colistin; Cr2, highest value of creatinine during treatment with colistin; Cr3, serum creatinine 7 days after completion of treatment with colistin; CVVHD, continuous ... for the severity of illness. Because mortality rates in the region of 50–60% have been reported in critically ill patients receiving inappropriate treat- ment [1–7],...

Ngày tải lên: 12/08/2014, 19:22

... colistin as monotherapy; she had received intravenous colistin therapy before aerosolized colis- tin for 7 days and continued to receive the intravenous therapy after the end of aerosolized therapy ... creatinine value (mg/dl) on the first day of aerosolized colistin administration 1.1 5.2 1 0.4 2.4 0.6 0.8 0.8 Serum creatinine value (mg/dl) at the end of aerosolized...

Ngày tải lên: 12/08/2014, 20:21

... abandonment of colistin in clinical practice. As a consequence there is only a paucity of physicians with clinical experience in the use of this class of antimicrobials. The spectrum of activity of the ... describe the use of inhaled colistin in the treatment of multidrug-resistant Gram-negative nosocomial pneumonia in a small group of patients. Alt...

Ngày tải lên: 12/08/2014, 20:21

... MDM2, thus mimicking the binding of the helical portion of p53. However, one of the enanti- omers of this racemic mixture of compounds was found to possess higher affinity for the binding site as ... summarizes the growing body of knowledge regarding novel therapeutic targets, enabling the concept of individualized targeted therapy for the treatment of FL. Intr...

Ngày tải lên: 10/08/2014, 22:20

... adaptations in the eye in the human lineage. In addition to the evolution of cN and cS crystal- lins, even more specialization in the c-crystallins has occurred with the loss of the N-terminal arm in the ancestor ... lost the intron dividing the exons encoding the first domain. The next step in the evolu- tion of the c-crystallins was cS-crystallin,...

Ngày tải lên: 19/02/2014, 17:20

... activity of the re-grown clones was deter- mined again by incubating the activated CPU at 37 °C and using the same protocol as used in the primary screening described above. Determination of the half-life ... mutations in the region following position 314 in CPU. Fifty per cent of the residues mutated in the clones selected from the first round of FIND TM ar...

Ngày tải lên: 07/03/2014, 12:20

... distribution of BsArb43B in the proximity of the active site. Arabinotriose in the binding cleft is represented using sticks. (B) Detailed view of the binding cleft with arabinotri- ose. (C) Details of the ... with arabinohexose [15], this loop makes the reducing end of the carbohydrate chain bend towards the solvent, probably optimizing binding of the carboh...

Ngày tải lên: 15/03/2014, 23:20

... frame encoded by the PR-1a gene, and differs by only six amino acids from the PR-1a preprotein in the N-terminal moiety of the protein. Most importantly, the W38-1 pseudogene part of the W38-1::PR-1a ... a distinct host response depending on the genetic constitution of the plant and the pathogen. In an incompatible inter- action, the pathogen remains localized...

Ngày tải lên: 23/03/2014, 15:21

... a certain level of TRa (Fig. 6A). As in the HeLaTR cells, T3 treatment of the FRTL cells significantly increased the level of the 4-1BB mRNA and decreased the level of the BMP6 mRNA. Furthermore, ... modulated during both early and late responses. We also examined the expression of TRAF1 and TRAF2 because they interact and regulate the function of the 4-1BB pr...

Ngày tải lên: 23/03/2014, 18:20

... ap- plied to the links extracted from the dictionary. Indeed, while the synonymy is sometimes very contextual in the dictionary, the links appear in the data without context information and ... of wrong links is rather important in the list presented to the expert: between 10 to 20 links out of 396. On the contrary, about ten wrong links are due to the e...

Ngày tải lên: 23/03/2014, 19:20