Báo cáo y học: "Science review: Apoptosis in acute lung injury" potx

... link apoptosis with the pathogenesis of acute lung injury in humans. The first of these, namely the ‘neutrophilic hypothesis’, suggests that during acute inflammation the cytokines granulocyte ... outcome in acute lung injury. Phagocytosis of apoptotic neutrophils and release of cytokines by macrophages The third mechanism whereby apoptosis of neutrophils can modify the infl...

Ngày tải lên: 12/08/2014, 19:22

... Pulmonology, and Nephrology, Yamagata University School of Medicine, Yamagata, Japan 2. Division of Clinical Laboratory, Yamagata University Hospital, Yamagata, Japan  Corresponding author: Dr. Yoko ... pneumo- nia, infiltrating neutrophils produce pro-inflammatory cytokines and chemokines, result- ing in the induction of cellular adhesion molecules on circulating leukocytes and pulmon...

Ngày tải lên: 08/08/2014, 18:21

... in the majority of patients with acute lung injury and the acute respiratory distress syndrome. Am J Respir Crit Care Med 2001, 163:1376-1383. 7. McAuley DF, Frank JA, Fang X, Matthay MA: Clinically ... 60-day mortality between treatment groups. The study was stopped by the Data Monitoring Board at the first interim analysis for futility following 279 patients who received the study d...

Ngày tải lên: 13/08/2014, 20:21

... of such systems outside the conventional indication of acute life-threatening hypoxemia. Ever since its original description by Daniel Ashbaugh and co-workers in 1967 [2], hypoxemia in spite ... widening indications with the aim of reducing ventilator induced lung injury (VILI) is still controversial. Consequently, technological progress is an important strategy. Miniaturized ECM...

Ngày tải lên: 13/08/2014, 20:21

... sensitivity and specificity, the ability of VPW to discriminate fluid status in patients with acute lung injury is limited and should only be considered when intravascular pressures are unavailable. Introduction The ... LVEDV is widely presumed, this is not the case in a number of conditions pertinent to acute lung injury, including sep- sis [25-27], trauma [28], and acute respi...

Ngày tải lên: 14/08/2014, 07:21

... ventilation in patients with ARDS and acute lung injury. Keywords acute lung injury, acute respiratory distress syndrome, alveolar epithelium, mechanical ventilation, ventilator-induced lung injury 237 that ... online http://ccforum.com/content/7/3/233 Table 2 Clinical definition of acute respiratory distress syndrome and acute lung injury [76] Clinical feature Acute res...

Ngày tải lên: 12/08/2014, 19:21

... considered as an insult fre- quently leading to systemic inflammatory response syn- drome including the systemic release of proinflammatory cytokines which is central in t he inflammatory response. Previous ... frequently induces a s ystemic inflammatory response syndrome (SIRS) that results in multiple-organ dysfunction syndrome (MODS) [1,2] including acute lung injury (ALI), which i...

Ngày tải lên: 10/08/2014, 09:21

... with acute lung injury and to 29/33 (88%) of those with acute respiratory distress syndrome. Lung injury patients had higher mortality than others (acute lung injury 25.0%; acute respiratory distress ... to lung injury, both inside and outside the intensive care unit. Patients were followed prospectively for outcomes, including the diagnosis of acute lung injury or acute...

Ngày tải lên: 13/08/2014, 08:20

... clinical outcomes. Albumin with furosemide benefits lung physiology in hypoproteinemic patients with acute lung injury /acute respiratory distress syndrome, but the independent pharmacologic ... determine the independent pharmacologic effects of albumin and furosemide in hypoproteinemic patients with acute lung injury /acute respiratory distress syndrome. Design: Random...

Ngày tải lên: 13/08/2014, 08:20

... (pericytes, cardiomyocytes, smooth muscle cells, keratinocytes) and by vascular monocytes and endothelial cells upon induction by inflammatory cytokines or endotoxin [3]. TF is the high-affinity cellular ... efficacy in providing anti-inflammatory benefit in sepsis. Anticoagulants (shown in red and boxed) showed preclinical efficacy in preventing lethality, whereas anticoagulant mecha...

Ngày tải lên: 12/08/2014, 19:21