Báo cáo y học: "Involvement of RhoA-mediated Ca2+ sensitizat

Báo cáo y học: "Regulation of the cd38 promoter in human airway smooth muscle cells by TNF-α and dexamethasone" pot

... regard, airway smooth muscle has a role in the regulation of airflow and in maintaining airway caliber. Airway smooth muscle contractility TNF-α-induced activation and specific binding of AP-1 to ... the Specific binding of GR to cd38 putative GRE binding sitesFigure 4 Specific binding of GR to cd38 putative GRE binding sites. Electrophoretic mobility gel shift assays demo...

Ngày tải lên : 12/08/2014, 15:21

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Báo cáo y học: " Involvement of the genicular branches in cystic adventitial disease of the popliteal artery as a possible marker of unfavourable early clinical outcome: a case report" pps

... adventitial cyst to become symptomatic involves a sufficient increase of the pressure within the fluid-filled cyst during muscle exertion, thus resulting in haemodynamically significa nt endoluminal ... col- lections of mucinous material con taining varying combi- nations of mucopolysaccharides and mucoproteins within the adventitial layer of the artery. The cysts exert extrinsic...

Ngày tải lên : 11/08/2014, 12:20

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Báo cáo y học: "Involvement of nitric oxide (NO) in cough reflex sensitivity between non-sensitized and OVA-sensitized guinea pigs" pptx

... sensitivity in non- sensitized guinea pigs and OVA-induced increase in cough reflex sensitivity in sensitized guinea pigs; however, iNOS inhibition caused by ONO1714 partially suppressed the OVA-induced ... needed to clarify the precise mechanism. Background Nitric oxide (NO) may p lay an essential role in regula t- ing airway funct ion and in the pathophysiology of inflammatory a...

Ngày tải lên : 13/08/2014, 10:20

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Tài liệu Báo cáo Y học: Toxicity of substrate-bound amyloid peptides on vascular smooth muscle cells is enhanced by homocysteine docx

... toxic to neurons in culture by increasing the vulnerability of these cells to excitotoxic and oxidative injury [50]. In smooth muscle cells, homocysteine can increase production of nitric oxide ... on plastic alone, indicating that cell–substrate adhesion may be important in maintaining cell viability. Ab also caused an increase in the number of apoptotic cells. This increas...

Ngày tải lên : 22/02/2014, 07:20

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Báo cáo y học: " A novel small molecule target in human airway smooth muscle for potential treatment of obstructive lung diseases: a staged highthroughput biophysical screening" pps

... Eyk JE: cGMP- mediated phosphorylation of heat shock protein 20 may cause smooth muscle relaxation without myosin light chain dephosphorylation in swine carotid artery. Journal of Physiology-London ... changes in cell stiffness as measured by magnetic twisting cytometry. Function efficacy of small molecules on stiffness of ASM at the level of a single living cell. Figure S2:...

Ngày tải lên : 12/08/2014, 13:22

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Báo cáo y học: "Evidence that CFTR is expressed in rat tracheal smooth muscle cells and contributes to bronchodilation" pptx

... n = 4. C Immunofluorescence study of CFTR in TSMC and D in the absence of primary antibody. α -smooth muscle actin is stained in red, CFTR in green and nucleus (TOPRO-3 staining) in blue. Scale ... to airway smooth muscle in CF. They shown increased smooth muscle content of the airway in subjects with CF compared to healthy controls. This increase is due to s...

Ngày tải lên : 12/08/2014, 16:20

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Báo cáo y học: "Involvement of RhoA-mediated Ca2+ sensitization in antigen-induced bronchial smooth muscle " pdf

... sensitization of murine bronchial smooth muscleFigure 2 Acetylcholine (ACh)-induced Ca 2+ sensitization of murine bronchial smooth muscle. (A) A typical recording of contraction induced by ... to understand changes in the contractile signaling of airway smooth muscle cells associated with the disease. Smooth muscle contraction including airways is mainly regula...

Ngày tải lên : 12/08/2014, 18:21

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Báo cáo Y học: Oxidation of propionate to pyruvate in Escherichia coli Involvement of methylcitrate dehydratase and aconitase pot

... [29]. Interestingly, two enzymes are involved in the conversion of methylcitrate into 2-methylisocitrate. PrpD is involved in the dehydration of (2S,3S)-methylcitrate to 2-methyl-cis- aconitate. The elimination ... 2002 2-methyl-cis-aconitate) in the coupled assay with the activity of the back reaction measured by the dehydration of chemically synthesized threo-2-methylisocitrat...

Ngày tải lên : 17/03/2014, 10:20

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Báo cáo Y học: Inhibition of SERCA Ca2+ pumps by 2-aminoethoxydiphenyl borate (2-APB) 2-APB reduces both Ca2+ binding and phosphoryl transfer from ATP, by interfering with the pathway leading to the Ca2+-binding sites ppt

... indicates a crucial role for the hydroxyl group of this tyrosine residue in the binding of 2-APB to the enzyme. DISCUSSION 2-APB has been used extensively recently to investigate ... Ca 2+ bindingbyboth reducing the rate constant for binding as well as increasing therateconstantforCa 2+ dissociation, could be explained by 2-APB binding to either one or both of these sites. In ... FE...

Ngày tải lên : 31/03/2014, 23:20

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Báo cáo y học: " Involvement of mTOR signaling in sphingosylphosphorylcholine-induced hypopigmentation effects" pps

... 18:55 http://www.jbiomedsci.com/content/18/1/55 Page 7 of 8 RESEARC H Open Access Involvement of mTOR signaling in sphingosylphosphorylcholine-induced hypopigmentation effects Hyo-Soon Jeong 1 , Seung Hoon Lee 1 , Hye-Young Yun 1 , Kwang Jin Baek 1 , ... by freezing and thawing. After quantifying t he protein levels of the lysate and adjusting the protein concen- trations with lysis b...

Ngày tải lên : 10/08/2014, 10:20

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