Báo cáo y học: "A mechanism of airway injury in an epithelial model of mucociliary clearance" doc
Báo cáo y học: "A mechanism of airway injury in an epithelial model of mucociliary clearance" doc
... 3).DiscussionThe important findings of this study are: 1. the develop-ment of a model of airway epithelial injury that can beused for study of ultra-structural and molecular events in airway injury that are ... activated in the tissue is another important question. An understand-ing of this injury mechanism may lead to ways to inter-vene in the early stages of airway diseases withsymptomatic signs of impaired ... which have been shown to playa role in airway injury and remodeling [7,8] and in cell-signaling pathways [14].Materials and MethodsDevelopment of a frog palate injury model A fresh frog palate...
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Báo cáo y học: " A novel small molecule target in human airway smooth muscle for potential treatment of obstructive lung diseases: a staged highthroughput biophysical screening" pps
... changes in cell stiffness usingmagnetic twisting cytometry (MTC) and changes in celltraction force using Fourier transform traction micro-scopy (FTTM). Finally, scaling up to the level of an intact ... (GrandIsland,NY).Thesyntheticarginine-glycine-aspartic acid(RGD) containing peptide was purchased from AmericanPeptide Company (Sunnyvale,CA).Primaryantibodiesagainst HSP20, cofilin, phospho rylated cofilin and 14-3-3g proteins, as well as the ... Kayyali US, Gaestel M,Shore SA, Fredberg JJ: Role of heat shock protein 27 in cytoskeletalremodeling of the airway smooth muscle cell. Journal of AppliedPhysiology 2004, 96:1701-1713.36. Dandurand...
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Tài liệu Báo cáo Y học: Soluble silk-like organic matrix in the nacreous layer of the bivalve Pinctada maxima A new insight in the biomineralization field pptx
... the mean of at least three independentdeterminations. Cysteine and tryptophan were not determined. Hydroxyproline, hydroxylysine and phosphoserine were not detected in all samples.Amino acidWater-solublematrixWater-insolublematrixEDTA-solublematrixEDTA-insolublematrixAsx ... Nevertheless, they wereaspartic-rich in EDTA-SM whilst being quite glutamic acid-rich in WSM.Glycosaminoglycan analysisGlycosaminoglycans are highly negatively charged because of the presence of sulfate ... predominance of acidic glycoproteins. It is known asintracrystalline and is considered to play an important role in induction of oriented nucleation, inhibition of crystalgrowth and control of aragonite-calcite...
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Tài liệu Báo cáo Y học: A novel, inducible, citral lyase purified from spores of Penicillium digitatum docx
... convert the proposed intermediate (4-hydroxy-3-methoxyphenyl-b-hydroxypropionyl-CoA) into vanillin[28]. An other well known example is trans-o-hydroxy-benzylidenepyruvate hydratase/aldolase [29,30] ... best of ourknowledge, the induction of an enzymatic activity in nongerminating spores has so far only been described in spores of Aspergillus oryzae,i.e.a-amylase, invertase andglucose dehydrogenase ... induction.Stability of citral lyase activityThe activity and stability of citral lyase was dramaticallyaffected by the addition of 20% (v/v) glycerol and 1 mMEDTA. When glycerol and EDTA were...
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Báo cáo Y học: A new high affinity binding site for suppressor of cytokine signaling-3 on the erythropoietin receptor potx
... specifically interactwith the tyrosine motifs pY401 and pY429pY431.pY429pY431 was more potently recruiting SOCS-3 thanpY401, reflecting the high affinity binding determined bySPR. The nonphosphorylated ... phosphotyrosinesbind to the phosphotyrosine binding pocket of the SH2domain, with R94 only playing a minor role in thebinding of these peptides.DISCUSSIONThe cytoplasmic part of the EpoR contains ... pY431 appears to increasethe binding affinity by providing an additional contact withthe SH2 domain of SOCS-3 involving R94. A conforma-tional change induced by the phosphorylation of tyrosine Y4 31...
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Báo cáo Y học: A single charged surface residue modifies the activity of ikitoxin, a beta-type Na+ channel toxin from Parabuthus transvaalicus doc
... For analysis, matrix solutions consisting of sinapinic acid, 3,5-dimethoxy-4-hydroxycinnaminic acid,or a-cyano-4-hydroxycinnamic acid, were mixed in a 1 : 1ratiowithsamples,spottedonthetargetandallowedtodry.MASSLYNX(Micromass ... previ-ously for birtoxin [6]. Brie y, the cysteine residues of thepeptide were reduced and carboxymethylated by incubating in 6Mguanidine hydrochloride, 0.1MTris/HCl (pH 8.3),1mMEDTA and 20 ... again observed in the case of birtoxin and ikitoxin. Moskowitz et al. [18]cautioned that minor changes in primary structure can leadto major changes in mode of action and that groups of toxinsbased...
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Báo cáo y học: "A proinflammatory role for Fas in joints of mice with collagen-induced arthritis" docx
... proinflammatorycytokines TNF-α and IL-6 was increased. These findingssuggest that impairment of immune tolerance by increased T-cell reactivity does not lead to enhanced susceptibility to CIAand point ... disease by destroying target tissues throughinduction of apoptosis of chondrocytes [33]. Alternatively,Fas could contribute to synovial hyperplasia by inducingproliferation of Fas-expressing synovial ... apoptosis induced by anti-Fas mAb and is accompa-nied by increased expression of TNF-α and IL-6,suggesting an activating effect by Fas ligation. Fascrosslinking may contribute to cartilage and bone...
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Báo cáo y học: "A mouse embryonic stem cell bank for inducible overexpression of human chromosome 21 genes." ppsx
... Overexpres-sion of a number of HSA21 genes, including Dyrk1a,Synj1 and Sim2, results in learning and memory defects in mouse models, suggesting that trisomy of these genesmay contribute to learning disability ... genes, which can be overexpressed in an inducible manner. Each clone was transcriptionally profiled in inducing versus non-inducing conditions. Analysis of the transcriptional response yielded results ... syndrome and other human aneuploidy disorders.BackgroundAneuploidy refers to an abnormal copy number of genomic elements, and is one of the most commoncauses of morbidity and mortality in humans...
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Báo cáo y học: "Severe community-acquired adenovirus pneumonia in an immunocompetent 44-year-old woman: a case report and review of the literature" ppsx
... human metap-neumovirus, PIV, human rhinovirus and human corona-virus play an important role in the etiology of community-acquired pneumonia in adults [33]. Theincreasingly widespread use of ... nasopharyngeal and tracheal samples were negativefor influenza A and B (including H1N1), respiratory syn-cytial virus (RSV) types A and B and parainfluenza virus(PIV) types 1 thr ough 4, but they ... assisted in thewriting of the manuscript. MJW oversaw the study and assisted with thewriting of the manuscript. All authors read and approved the final version of the manuscript.Competing interestsThe...
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Báo cáo y học: "A novel method to identify and characterise peptide mimotopes of heat shock protein 70-associated antigens" pptx
... amphotericin B in the presence of 60 ng/mLrecombinant human granulocyte macrophage colonystimulating factor (GM-CSF) and 150 ng/mL recombinanthuman IL-4. Medium and cytokines were replaced every 2days. ... 20:4169-4180.22. Austin E, Robins R, Baldwin R, Durrant L: Induction of delayedhypersensitivity to human tumor cells with a human mono-clonal anti-idiotypic antibody. J Natl Cancer Inst 1991,83:1245-1248.23. ... Sreedharan S, Mohanty K,Bhattacharya-Chatterjee M: Dendritic Cells Pulsed with an Anti-Idiotype Antibody Mimicking Carcinoembryonic Antigen(CEA) Can Reverse Immunological Tolerance to CEA andInduce...
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Từ khóa: báo cáo y họcbáo cáo y học cổ truyềnthe role of capital market in facilitating the process of economic growth in nigeriabáo cáo khoa học y họcbáo cáo y tế học đườngmẫu báo cáo y tế học đườngBáo cáo thực tập tại nhà thuốc tại Thành phố Hồ Chí Minh năm 2018Nghiên cứu sự biến đổi một số cytokin ở bệnh nhân xơ cứng bì hệ thốngBáo cáo quy trình mua hàng CT CP Công Nghệ NPVNghiên cứu sự hình thành lớp bảo vệ và khả năng chống ăn mòn của thép bền thời tiết trong điều kiện khí hậu nhiệt đới việt namNghiên cứu vật liệu biến hóa (metamaterials) hấp thụ sóng điện tử ở vùng tần số THzNghiên cứu tổ chức chạy tàu hàng cố định theo thời gian trên đường sắt việt namGiáo án Sinh học 11 bài 13: Thực hành phát hiện diệp lục và carôtenôitGiáo án Sinh học 11 bài 13: Thực hành phát hiện diệp lục và carôtenôitQuản lý hoạt động học tập của học sinh theo hướng phát triển kỹ năng học tập hợp tác tại các trường phổ thông dân tộc bán trú huyện ba chẽ, tỉnh quảng ninhPhát triển mạng lưới kinh doanh nước sạch tại công ty TNHH một thành viên kinh doanh nước sạch quảng ninhPhát triển du lịch bền vững trên cơ sở bảo vệ môi trường tự nhiên vịnh hạ longPhát hiện xâm nhập dựa trên thuật toán k meansNghiên cứu khả năng đo năng lượng điện bằng hệ thu thập dữ liệu 16 kênh DEWE 5000Thiết kế và chế tạo mô hình biến tần (inverter) cho máy điều hòa không khíSở hữu ruộng đất và kinh tế nông nghiệp châu ôn (lạng sơn) nửa đầu thế kỷ XIXTổ chức và hoạt động của Phòng Tư pháp từ thực tiễn tỉnh Phú Thọ (Luận văn thạc sĩ)Quản lý nợ xấu tại Agribank chi nhánh huyện Phù Yên, tỉnh Sơn La (Luận văn thạc sĩ)Giáo án Sinh học 11 bài 15: Tiêu hóa ở động vậtBÀI HOÀN CHỈNH TỔNG QUAN VỀ MẠNG XÃ HỘIQUẢN LÝ VÀ TÁI CHẾ NHỰA Ở HOA KỲ