Báo cáo y học: "spondyloarthritis suggests that the innate immune pathway might be of greater relevance than the Th17-mediated adaptive immune response" doc
Báo cáo y học: "spondyloarthritis suggests that the innate immune pathway might be of greater relevance than the Th17-mediated adaptive immune response" doc
... al.: Analysis of IL-17 + cells in facet joints of patients with spondyloarthritis suggests that the innate immune pathway might be of greater relevance than the Th17-med iated adaptive immune response. ... of 9 RESEARCH ARTICLE Open Access Analysis of IL-17 + cells in facet joints of patients with spondyloarthritis suggests that the innate immu...
Ngày tải lên: 12/08/2014, 17:21
Báo cáo y học: "Kinematic and dynamic gait compensations in a rat model of lumbar radiculopathy and the effects of tumor necrosis factor-alpha antagonis" ppsx
... altered by habituation to the gait test, or affected by stress associated with limb injury in the rat. The reasons for this inconsistency are not clear and are far beyond the scope of this study. ... characterization can be used to describe limb dysfunction occurring during the early stages of lumbar radiculopathy in the rat, and that, gait metrics and dynamics may be...
Ngày tải lên: 12/08/2014, 17:22
Báo cáo y học: "Cell-specific microarray profiling experiments reveal a comprehensive picture of gene expression in the C. elegans nervous system" ppsx
... with the embryonic profile of specific thermosensory neurons (AFD and AWB described by Colosimo et al. [8]. The AFD/AWB profile shows greater overlap with the EP dataset (e) than with the EA ... detected in the profile of the entire nervous system. This finding suggests that indi- vidual neurons may express rare transcripts that are likely to be restricted to sp...
Ngày tải lên: 14/08/2014, 07:22
Báo cáo Y học: Nuclear proteins that bind to metal response element a (MREa) in the Wilson disease gene promoter are Ku autoantigens and the Ku-80 subunit is necessary for basal transcription of the WD gene ppt
... MREe in the forward orientation, and MREc and MREd in reverse orientation. The effects of the mutiple MREs on promoter activity of the MT gene have been shown to be dependent on the position of the ... determine whether the MREa– protein complex displays sequence specificity. Binding of the HepG2 nuclear proteins to MREa was inhibited by the addition of a molar ex...
Ngày tải lên: 17/03/2014, 23:20
Báo cáo Y học: Amphibian peptides that inhibit neuronal nitric oxide synthase The isolation of lesueurin from the skin secretion of the Australian Stony Creek Frog Litoria lesueuri docx
... In addition, these peptides also inhibit the activity of calcineurin, another enzyme that requires the presence of the regulatory protein Ca 2+ calmodulin. It i s p roposed that the amphibian ... determine the in¯uence o f the calmodulin on th e inhibition of nNOS. These experi- ments measured nNOS activity in the presence of 142.9 lgámL )1 of the a ctive p eptid...
Ngày tải lên: 31/03/2014, 15:20
Báo cáo y học: "he enigma that is the nucleus pulposus cell: the search goes on" pptx
... than strict germ layer derivation suggests that, with respect to the identity of NP cells, there may be more than meets the eye [2]. e notochord derives from all three germ layers as it originates ... previously thought? The paper by Gilson and colleagues that is the subject of the present editorial presents compelling data concerning the heterogeneity of...
Ngày tải lên: 12/08/2014, 12:20
Báo cáo y học: "Elevated plasma homocysteine is positively associated with age independent of C677T mutation of the methylenetetrahydrofolate reductase gene in selected Egyptian subjects"
... Frequency of the MTHFR genotypes and the result of the Chi square testing in the different studied groups. Showing the frequency and the results of the cross tabulation of the T allele and the different ... difference in the occurrence of the TT genotype in any of the studied groups (P>0.05). Also the prevalence of the different genotypes did n...
Ngày tải lên: 03/11/2012, 09:49
Báo cáo Y học: Rapid caspase-dependent cell death in cultured human breast cancer cells induced by the polyamine analogue N1,N11-diethylnorspermine pdf
... activities. The function of the polyamines has been studied by the use of different biosynthesis inhibitors [1,6]. A d isadvantage of using t hese inhibitors alone is that they usually fail to deplete the ... cellular pools of putres- cine, spermidine and spermine by down-regulating the activity of the polyamine biosynthetic enzymes a nd up-regu- lating the activity...
Ngày tải lên: 17/03/2014, 23:20
Báo cáo Y học: A new high affinity binding site for suppressor of cytokine signaling-3 on the erythropoietin receptor potx
... interact with the tyrosine motifs pY401 and pY429pY431. pY429pY431 was more potently recruiting SOCS-3 than pY401, reflecting the high affinity binding determined by SPR. The nonphosphorylated peptide Y4 2 9Y4 31 ... number of SH2 domains. As the members of the Src family also carry a positively charged residue at this position, we favour the idea that the enhanced bindin...
Ngày tải lên: 24/03/2014, 00:21
Báo cáo Y học: Dietary bisphenol A prevents ovarian degeneration and bone loss in female mice lacking the aromatase gene (Cyp19 ) pptx
... have shown that exposure of pregnant mice to environmental levels of BPA (2.4 lgÆkg body weight )1 ) advanced the puberty of the offspring pups. Assuming that the mean body weight of adult ArKO ... approximately 2.5-fold and five- fold over that of the untreated ArKO mice, respectively. The uterine weight of the ArKO mice fed the 1% BPA-diet was comparable to t...
Ngày tải lên: 24/03/2014, 03:21