Báo cáo sinh học: "WildSpan: mining structured motifs from protein sequences" doc

... Access WildSpan: mining structured motifs from protein sequences Chen-Ming Hsu 1 , Chien-Yu Chen 2* and Baw-Jhiune Liu 3 Abstract Background: Automatic extraction of motifs from biological sequences ... Z: Protein- Protein Docking Benchmark 2.0: an update. Proteins 2005, 60(2): 214-216. 28. Hsu CM, Chen CY, Liu BJ, Huang CC, Laio MH, Lin CC, Wu TL: Identification of hot regions...

Ngày tải lên: 12/08/2014, 17:20

... template. Extraction of the structured motifs We extract the structured motifs by doing positional joins on the pos-lists of the simple motifs from the end to the start in the structured motif . Formally, ... Corresponding author Abstract Background: Extracting motifs from sequences is a mainstay of bioinformatics. We look at the problem of mining structured motifs, w...

Ngày tải lên: 12/08/2014, 17:20

... [3], describe a new algo- rithm called EXMOTIF to extract frequent motifs from DNA sequences. The method can mine structured motifs and profiles which have variable gaps between different elements. ... Algo- rithm for Protein- Protein Interaction Networks, Woochang Hwang, Young-Rae Cho, Aidong Zhang and Murali Ram- anathan [5], describe the unexpected properties of the protein- prot...

Ngày tải lên: 12/08/2014, 17:20

... profession- als. Doctors from Francophone African countries may face language barriers or other impediments in the destination countries with the most opportunities for foreign doctors. Zimbabwe ... recruitment of doctors and nurses [5]. Philip Martin, Manolo Abella, and Christiane Kuptsch assert that South Africa is "suffering" from a "brain drain" of doctors and nurs...

Ngày tải lên: 18/06/2014, 17:20

... countries via an online survey instru- ment. Four persons from different but relevant perspec- tives will be targeted to participate from each country. The project team is working actively with ... profes- sional group in the world after nurses and doctors. The ratio of the pharmacy workforce to population varies widely between countries, from 0.8 per 10 000 popula- tion in the African...

Ngày tải lên: 18/06/2014, 17:20

... projected that the number of doctors in the Japanese medical workforce would reach 368 196 Table 3 Number of new doctors from foreign medical schools Year All new doctors From foreign schools Percentage 2000 ... to resolve the current doctor shortage and will exacerbate the doctor surplus of the future. It would be more constructive to accelerate the flow of medical doc- tors from oth...

Ngày tải lên: 18/06/2014, 17:20

... of PAdV-3 E1B large protein on binding of NF-κB protein to an oligonucleotide con- taining the IL-8 NF-κB DNA sequence [26,27], initially, we analyzed the nuclear extracts from transfected and nontransfected ... Similar homology is reported between African swine fever virus encoded IκB (A238L) protein and porcine IκB protein [29]. Alterna- tively, the nuclear localization of E1B lar...

Ngày tải lên: 18/06/2014, 18:20

... pre- cursor protein (p21K) into a 21 kDa peptide (21 K) and additional cleavage at the C-terminal AG/N site is cata- lyzed by the I7L core protein proteinase [9]. G7L also uti- lizes two distinct motifs, ... to identify the proteins. As a result, a variety of different VV proteins with sequence coverage from 12 to 55% were obtained, which is above the minimum cover- age (5%) for prote...

Ngày tải lên: 18/06/2014, 18:20

... alphaherpesvirus envelope proteins from plasma membranes to the TGN [32-36]. The acidic cluster motifs appear to direct TGN localization by binding to a cellular connector protein, PACS-1, which ... interactions with other proteins [30]. Furthermore, the amino terminus of UL20p contains acidic clusters, as well as the amino acid motif YXXΦ (YSRL), which have been shown to function in end...

Ngày tải lên: 18/06/2014, 18:20

... Antibody to mouse CD71 was purchased from ebioscience and to caveolin from BD Bio- science. Fluorescein isothiocyanate (FITC)-conjugated goat anti rat IgG was obtained from Sigma and Texas Red labelled ... by the viral Gag polyprotein [28], thus virus-like particles are formed in the absence of any other viral proteins or genome. Since, the spatial neighbourhood of Env and Gag proteins...

Ngày tải lên: 19/06/2014, 08:20