Báo cáo sinh học: " Local sequence alignments statistics: deviations from Gumbel statistics in the rare-event tail" pps

... devi- ations from the Gumbel distribution become visible in the tail. The dotted lines show the original Gumbel distribution, when fitted to the region of high probability. The inset shows the same ... g (l) the gap-cost function with g (0) = 0. Note that the alignment is local, because the (possibly large) gaps at the beginning and the end of each sequence...

Ngày tải lên: 12/08/2014, 17:20

... responsible. The most recent of these occurred in June of 2005 in the state of Indiana. Other outbreaks in the Americas include Mexico in 1988 and more recently, in 2004, Uruguay and Cuba. As with other ... isolates from New York and Utah in the same year, while both grouping within the RHDVa clade, did not branch together indicating separate origins for these outbreak...

Ngày tải lên: 18/06/2014, 18:20

... the window size increases from two to eight genes, the net number of genes in groups (that is, the genes in groups in the ordered dataset minus genes in groups from the random dataset) increases ... preventing their influence from being propagated along the chromosome. It is not known how common insulators are in the Drosophila (or any other) genome. Some insulat...

Ngày tải lên: 06/08/2014, 18:20

... from the antenna into the ordinary glomeruli (Ord) of the antennal lobe. Inhibitory GABA-ergic local interneurons form a network cross-linking all the antennal lobe glomeruli and help shape the ... emerging from each glomerulus via projection interneurons. The axons of these projection interneurons project in a single tract to the back of the brain to synapse first wit...

Ngày tải lên: 06/08/2014, 18:21

... yet included in the canine standard karyotype. The banding pattern of this chromosome is shown in figure 1A. In the male karyotype, a NOR occurred also in the terminal ... NORs were localized in the terminal part of the q arms of chromosome pairs: 7 and 17. The third chromosome pair, also bearing NORs in the terminal part of...

Ngày tải lên: 09/08/2014, 18:22

... the so-called genetic conservation index and minimize the inbreeding coefficient of the hypothetical offspring of the couple. © Inra/Elsevier, Paris donkey / endangered ... from inbreeding. Therefore, the two priorities accounted for in the Catalonian donkey breed Conservation Programme are: 1) keeping the maximum genetic diversity, 2...

Ngày tải lên: 09/08/2014, 18:22

... protein was predicted to recognize the aforemen- tioned 13-mer motif CCNCCNTNNCCNC in a zinc fin- ger binding array. The f ast evolution of Prdm9 protein and its binding motif can explain the ... repairing a small region (called the tract) f rom the chromosome that initiates a double-strand break by copying from the other chromo- some. At the center of the tract was the...

Ngày tải lên: 09/08/2014, 22:23

... approximately at 240 bp from the beginning of intron 4 and the novel microsatellite, which included a tandem repeat of (TC) n is located approximately at 1264 bp from the beginning of intron 4. 3.3. Allele ... 72 ◦ C for 10 min. The purified PCR products were cloned into the pGEM-T vector (TaKaRa, Dalian, China) and were sequenced using standard M13 primers. DNA sequences were co...

Ngày tải lên: 14/08/2014, 13:22

... the asthmatic airway, their role in cough reflex sensitivity is controversial [19,22]. These findings indicate that arachidonate metabolites including prostaglandins may have variable roles in ... concentration of inhaled methacholine causing a 20% fall in FEV1. ** Bronchodilator response means percent increase in forced expiratory volume in 1s (FEV1) from the baseline value a...

Ngày tải lên: 13/08/2014, 08:20

... in the native structure and is the corresponding distance in the model and the summation runs over the N res aligned residues. Next, one defines a threshold, DME cut = 4.0 Å, bearing in mind ... class by calculat- ing the probability of each φ , ψ pair within the correspond- ing distributions that define the class and taking the product of these probabilities. Exact...

Ngày tải lên: 12/08/2014, 17:20