Báo cáo y học: "Canakinumab relieves symptoms of acute flares and improves health-related quality of life in patients with difficult-to-treat Gouty Arthritis by suppressing inflammation: results of a randomized, dose-ranging study" ppt
Báo cáo y học: "Canakinumab relieves symptoms of acute flares and improves health-related quality of life in patients with difficult-to-treat Gouty Arthritis by suppressing inflammation: results of a randomized, dose-ranging study" ppt
... article as: Schlesinger et al.: Canakinumab relieves symp toms of acute flares and improves health-related quality of life in patients with difficult-to-treat Gouty Arthritis by suppressing inflammation: results ... anti-inflammatory therapy on quality of life in patients with acute Gouty Arthritis and demo nstrates the significant v...
Ngày tải lên: 12/08/2014, 15:22
Báo cáo y học: " High Human T Cell Leukemia Virus Type-1(HTLV-1) Provirus Load in Patients with HTLV-1 Carriers Complicated with HTLV-1-unrelated disorders" docx
... Uemura A, Sugahara K, Nagai H, Murata K, Hasegawa H, Hirakata Y, Tsukasaki K, Yamada Y, Kamihira S: An ATL cell line with an IgH pseudo- rearranged band pattern by southern blotting: a pitfall of ... 19:4954-60. 12. Satoh M, Toma H, Sugahara K, Etoh K, Shiroma Y, Kiyuna S, Takara M, Matsuoka M, Yamaguchi K, Nakada K, Fujita K, Kojima S, Hori E, Tanaka Y, Kamihira S, Sato Y, W...
Ngày tải lên: 12/08/2014, 04:20
Báo cáo Y học: High affinity binding between laminin and laminin binding protein of Leishmania is stimulated by zinc and may involve laminin zinc-finger like sequences doc
... protein of Leishmania is stimulated by zinc and may involve laminin zinc-finger like sequences Keya Bandyopadhyay, Sudipan Karmakar, Abhijit Ghosh and Pijush K. Das Molecular Cell Biology Laboratory, ... i n enhancing laminin– enactin and laminin–collagen type I V binding. Previously, the enactin binding site was mapped to one of the zinc-finger containing repeats on t he laminin A...
Ngày tải lên: 08/03/2014, 23:20
Báo cáo Y học: Cellular stresses profoundly inhibit protein synthesis and modulate the states of phosphorylation of multiple translation factors potx
... control of mRNA translation in mammalian cells involves the regulation of a range of components of the translational machinery, principally by changes in their phosphorylation, leading to modulation ... 4E-BP1 and p70 S6k appear to lie on separate branches of this pathway [19]. p70 S6k is activated by insulin and growth factors (reviewed in [20]) and appears to pla...
Ngày tải lên: 18/03/2014, 01:20
Báo cáo Y học: Interaction between p21-activated protein kinase and Rac during differentiation of HL-60 human promyelocytic leukemia cell induced by all-trans-retinoic acid pdf
... all-trans-retinoic acid (ATRA). Manser et al.[7] have isolated a brain protein kinase, PAK68, by purifying a protein with Rac1/Cdc42-GTP binding ability. Because the kinase binds tightly to an affinity column ... differenti- ation of HL-60 cells induced with ATRA. Induction of Rac and PAK HL-60 cells were treated with 1 l M ATRA for a week, andRacandPAKwereassayedinbothcyto...
Ngày tải lên: 31/03/2014, 15:20
Báo cáo y học: "Innovative combination strategy to enhance effect and diminish adverse effects of glucocorticoids: another promise" pot
... fully synonymous with inflammatory and immunosuppressive activity and with adverse effects, respectively. For instance, hypopituitary- pituitary-adrenal axis suppression and increased risk of infection ... effects and adverse effects are manifold. Ultimately, the proof of the pudding is in the eating. Com- parative clinical trials of long duration with adequate numbers...
Ngày tải lên: 09/08/2014, 01:22
Báo cáo y học: "Glycogen synthase kinase 3, circadian rhythms, and bipolar disorder: a molecular link in the therapeutic action of lithium" docx
... (BPD) is a widespread condition characterized by recurring states of mania and depression. Lithium, a direct inhibitor of glycogen synthase kinase 3 (GSK3) activity, and a mainstay in BPD therapeutics, ... forward 5'-CAGCTTCCAGTCCCTGACTCAAG- GTTGTCCCACATAC-3', RevErb α reverse 5'-GGCGTA- GACCATTCAGCGCTTCATTATGACGCTGAG-3'; Bmal1 forward 5'-CCGTGCTAAG...
Ngày tải lên: 10/08/2014, 09:20
Báo cáo y học: "Objective Structured Clinical Examinations (OSCEs), psychiatry and the Clinical assessment of Skills and Competencies (CASC)Same Evidence, Different Judgement" ppsx
... long cases with each long case involving a partly observed interview of a real patient. Part II also involved an oral examination involving some standardized patient man- agement problems. Authors ... with standardized patients: state of the art. Teaching and Learning in Medicine 1990, 2:58-76. 16. Swanson DB, Norcini JJ: Factors influencing reliability of tests using stand...
Ngày tải lên: 11/08/2014, 15:22
Báo cáo y học: " The interaction between the PARP10 protein and the NS1 protein of H5N1 AIV and its effect on virus replication" pot
... members of PARP family have PARP activity and can modify part of protein in nuclei [9]. Studies also found that the protein family plays certain regulating role in DNA replication and repair [10,11], ... glutamate rich region and PARP domain (aa610-1025), and PARP domain (aa 691–1025). Nuclear export signal and two ubiquitin-binding motifs are located at the overlapping a...
Ngày tải lên: 11/08/2014, 21:22